World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
29116
World Ranking
2697
National Ranking
1399

Overview

Maria Febbraio is affiliated with the Cleveland Clinic in the United States and has contributed extensively to fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Dentistry. Their research spans several interdisciplinary subfields, notably Molecular Biology, Periodontics, Immunology, Neurology, and Cancer Research.

The body of work by Maria Febbraio addresses diverse scientific topics such as oral microbiology and periodontitis research, peroxisome proliferator-activated receptors, neuroinflammation and neurodegeneration mechanisms, adipokines related to inflammation and metabolic diseases, atherosclerosis and cardiovascular diseases, cancer, lipids and metabolism, and caveolin-1 involvement in cellular processes.

Recent notable publications include:

  • "Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking," 2021, JCI Insight
  • "Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets," 2020, Blood
  • "Is There a Causal Link Between Periodontitis and Cardiovascular Disease? A Concise Review of Recent Findings," 2021, International Dental Journal
  • "Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism," 2021, Frontiers in Cardiovascular Medicine
  • "Endothelial cell CD36 mediates stroke-induced brain injury via BBB dysfunction and monocyte infiltration in normal and obese conditions," 2023, Journal of Cerebral Blood Flow & Metabolism

Frequent coauthors in Maria Febbraio's research include Raisa Queiroz Catunda, Maria Alexiou, Liran Levin, Umar Rekhi, and Mohamed A. Omar, who have collaborated on multiple projects across the scientist's various areas of study.

The scientist's work has appeared repeatedly in journals such as the International Dental Journal, Frontiers in Cardiovascular Medicine, International Endodontic Journal, Frontiers in Immunology, and Scientific Reports. These venues reflect the interdisciplinary character of their research, spanning dentistry, cardiovascular medicine, immunology, and beyond.

Best Publications

  • CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

    Maria Febbraio;David P. Hajjar;Roy L. Silverstein

  • Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages

    Vidya V. Kunjathoor;Maria Febbraio;Eugene A. Podrez;Kathryn J. Moore

  • Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

    Maria Febbraio;Eugene A. Podrez;Jonathan D. Smith;David P. Hajjar

  • Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

    Benilde Jiménez;Olga V. Volpert;Susan E. Crawford;Maria Febbraio

  • CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

    Roy L. Silverstein;Maria Febbraio

  • A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

    Maria Febbraio;Nada A. Abumrad;David P. Hajjar;Kavita Sharma

  • Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice.

    Chris T. Coburn;F.F. Knapp;Maria Febbraio;Arnold L. Beets

  • CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions

    Fabienne Laugerette;Patricia Passilly-Degrace;Bruno Patris;Isabelle Niot

  • Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

    Jie Zhou;Maria Febbraio;Taira Wada;Yonggong Zhai

  • Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species

    Eugene A. Podrez;Maria Febbraio;Nader Sheibani;David Schmitt

  • A CD36-dependent signaling cascade is necessary for macrophage foam cell formation

    S. Ohidar Rahaman;David J. Lennon;David J. Lennon;Maria Febbraio;Evgeny A. Podrez

  • Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype

    Eugene A Podrez;Tatiana V Byzova;Maria Febbraio;Robert G Salomon

  • Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity

    Debby P Y Koonen;René L. Jacobs;Maria Febbraio;Martin E. Young

  • A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.

    Eugene A. Podrez;Eugenia Poliakov;Zhongzhou Shen;Renliang Zhang

  • CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima

    Young Mi Park;Maria Febbraio;Roy L. Silverstein

  • Oxidized phosphatidylserine–CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

    Michael E. Greenberg;Mingjiang Sun;Renliang Zhang;Maria Febbraio

  • Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo.

    Qi Ling;Andrew T. Jacovina;Arunkumar Deora;Maria Febbraio

  • Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system.

    Jens Husemann;John D. Loike;Roman Anankov;Maria Febbraio

  • Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration

    Blandine Franke-Fayard;Chris J. Janse;Margarida Cunha-Rodrigues;Jai Ramesar

  • Native and Modified Low Density Lipoproteins Increase the Functional Expression of the Macrophage Class B Scavenger Receptor, CD36 *

    Jihong Han;David P. Hajjar;Maria Febbraio;Andrew C. Nicholson

Frequent Co-Authors

Roy L. Silverstein
Roy L. Silverstein Medical College of Wisconsin
David P. Hajjar
David P. Hajjar Cornell University
Stanley L. Hazen
Stanley L. Hazen Cleveland Clinic Lerner College of Medicine
Jason R.B. Dyck
Jason R.B. Dyck University of Alberta
Sunghee Cho
Sunghee Cho Cornell University
Jonathan D. Smith
Jonathan D. Smith Cleveland Clinic
Tatiana V. Byzova
Tatiana V. Byzova Cleveland Clinic Lerner College of Medicine
Martha K. Cathcart
Martha K. Cathcart Cleveland Clinic Lerner College of Medicine
Marten H. Hofker
Marten H. Hofker University Medical Center Groningen
Maria M. Mota
Maria M. Mota University of Lisbon

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