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Joost J. F. P. Luiken

Joost J. F. P. Luiken

D-Index & Metrics

Medicine

D-Index
73
Citations
15470
World Ranking
19724
National Ranking
719

Overview

Joost J. F. P. Luiken is affiliated with Maastricht University in the Netherlands and has a research profile focused on biochemistry, genetics, molecular biology, and medicine. Their work primarily covers molecular biology and cardiology, with specific attention to physiology, surgery, and clinical biochemistry as subfields of study.

Their research spans diverse topics such as metabolism, diabetes, cancer, cardiovascular function and risk factors, peroxisome proliferator-activated receptors, mitochondrial function and pathology, adipose tissue and metabolism, ATP synthase and ATPases research, and pancreatic function related to diabetes.

Luiken's publication record includes contributions to several scientific journals. Frequent publication venues include:

  • International Journal of Molecular Sciences
  • Circulation Research
  • The FASEB Journal
  • Physiological Reviews
  • Molecular Metabolism

Some notable recent papers authored or co-authored by Luiken are:

  • Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance, 2020, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis, 2021, Molecular Metabolism
  • CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease, 2023, Physiological Reviews

Luiken often collaborates with other researchers, with frequent coauthors including Jan F. C. Glatz, Miranda Nabben, Shujin Wang, Francesco Schianchi, and Dietbert Neumann. This collaboration network supports multidisciplinary approaches in their research on metabolism and cardiac function.

Best Publications

  • Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

    Jan F. C. Glatz;Joost J. F. P. Luiken;Arend Bonen

  • Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36.

    Arend Bonen;Michelle L. Parolin;Gregory R. Steinberg;Jorge Calles-Escandon

  • Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling

    Joost J.F.P. Luiken;Susan L.M. Coort;Jodil Willems;Will A. Coumans

  • A novel function for fatty acid translocase (FAT)/CD36: involvement in long chain fatty acid transfer into the mitochondria.

    Shannon E. Campbell;Narendra N. Tandon;Gebretateos Woldegiorgis;Joost J.F.P. Luiken

  • Palmitate transport and fatty acid transporters in red and white muscles

    A. Bonen;J. J. F. P. Luiken;S. Liu;D. J. Dyck

  • Fatty acid transport across the cell membrane: Regulation by fatty acid transporters

    Robert W. Schwenk;Graham P. Holloway;Joost J.F.P. Luiken;Arend Bonen

  • Insulin Stimulates Long-Chain Fatty Acid Utilization by Rat Cardiac Myocytes Through Cellular Redistribution of FAT/CD36

    Joost J.F.P. Luiken;Debby P.Y. Koonen;Jodil Willems;Antonio Zorzano

  • Mechanisms and Regulation of Protein-Mediated Cellular Fatty Acid Uptake: Molecular, Biochemical, and Physiological Evidence

    Arend Bonen;Adrian Chabowski;Joost J. F. P Luiken;Jan F. C. Glatz

  • Insulin induces the translocation of the fatty acid transporter FAT/CD36 to the plasma membrane.

    Joost J. F. P. Luiken;David J. Dyck;Xiao-Xia Han;Narendra N. Tandon

  • Modest PGC-1α Overexpression in Muscle in Vivo Is Sufficient to Increase Insulin Sensitivity and Palmitate Oxidation in Subsarcolemmal, Not Intermyofibrillar, Mitochondria

    Carley R. Benton;James G. Nickerson;James Lally;Xiao-Xia Han

  • Dynamic role of the transmembrane glycoprotein CD36 (SR-B2) in cellular fatty acid uptake and utilization.

    Jan F. C. Glatz;Joost J. F. P. Luiken

  • Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification

    D. M. Ouwens;M. Diamant;M. Fodor;D. D. J. Habets

  • Uptake and metabolism of palmitate by isolated cardiac myocytes from adult rats: involvement of sarcolemmal proteins.

    J. J. F. P. Luiken;F. A. Van Nieuwenhoven;G. America;G. J. Van Der Vusse

  • Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise

    Graham P. Holloway;Veronic Bezaire;George J. F. Heigenhauser;Narendra N. Tandon

  • Greater Transport Efficiencies of the Membrane Fatty Acid Transporters FAT/CD36 and FATP4 Compared with FABPpm and FATP1 and Differential Effects on Fatty Acid Esterification and Oxidation in Rat Skeletal Muscle

    James G. Nickerson;Hakam Alkhateeb;Carley R. Benton;James Lally

  • Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats

    Susan L.M. Coort;Danny M. Hasselbaink;Debby P.Y. Koonen;Jodil Willems

  • Regulation of fatty acid transport by fatty acid translocase/CD36

    Arend Bonen;Shannon E. Campbell;Carley R. Benton;Adrian Chabowski

  • Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters.

    Joost J. F. P. Luiken;Susan L. M. Coort;Debby P. Y. Koonen;Dick J. van der Horst

  • From fat to FAT (CD36/SR-B2): Understanding the regulation of cellular fatty acid uptake.

    Jan F.C. Glatz;Joost J.F.P. Luiken

  • Apical CD36 Immunolocalization in Human and Porcine Taste Buds From Circumvallate and Foliate Papillae

    Peter J. Simons;J. Alain Kummer;Joost J.F.P. Luiken;Louis Boon

Frequent Co-Authors

Jan F. C. Glatz
Jan F. C. Glatz Maastricht University
Arend Bonen
Arend Bonen University of Guelph
Narendra N. Tandon
Narendra N. Tandon Cellphire Therapeutics
George J. F. Heigenhauser
George J. F. Heigenhauser McMaster University
Benoit Viollet
Benoit Viollet Institut Cochin
Lawrence L. Spriet
Lawrence L. Spriet University of Guelph
Michaela Diamant
Michaela Diamant VU University Medical Center
Didier Vertommen
Didier Vertommen Université Catholique de Louvain
Julian L. Griffin
Julian L. Griffin University of Aberdeen
Jos L. V. Broers
Jos L. V. Broers Maastricht University

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