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Medicine

D-Index
110
Citations
44827
World Ranking
5562
National Ranking
2995

Overview

E. Dale Abel is affiliated with the University of California, Los Angeles in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology. Specifically, their work focuses on molecular biology, cardiology and cardiovascular medicine, physiology, epidemiology, and surgery.

Their recent publications address a variety of topics including metabolic and cardiovascular disease mechanisms, imaging analysis techniques, and immune cell metabolism. Notable recent papers include Basic Mechanisms of Diabetic Heart Disease (2020, Circulation Research), A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ (2021, Cells), Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity (2020, Circulation Research), GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy (2021, Cancer Research), and The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming (2022, Cell Metabolism).

The subject collaborates regularly with several researchers, including Renata O. Pereira, Antentor Hinton, Margaret Mungai, Prasanna Katti, and Kit Neikirk. These collaborations appear across numerous publications, suggesting an active research network.

Their body of work is frequently published in several prominent journals and venues, with multiple contributions in bioRxiv (Cold Spring Harbor Laboratory), Circulation Research, Circulation, Diabetes, and the New England Journal of Medicine.

Their main fields of study are Medicine, with 156 publications, and Biochemistry, Genetics and Molecular Biology, with 139 publications. Subfields reflect a focus on aspects such as Molecular Biology (91 publications), Cardiology and Cardiovascular Medicine (48 publications), Physiology (44 publications), Epidemiology (21 publications), and Surgery (13 publications).

E. Dale Abel's research topics encompass areas such as:

  • Adipose Tissue and Metabolism
  • Cardiovascular Function and Risk Factors
  • Mitochondrial Function and Pathology
  • Metabolism, Diabetes, and Cancer
  • ATP Synthase and ATPases Research
  • Autophagy in Disease and Therapy
  • Pancreatic function and diabetes

Best Publications

  • Diabetic Cardiomyopathy Revisited

    Sihem Boudina;E. Dale Abel

  • Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

    E Dale Abel;Odile Peroni;Jason K. Kim;Young Bum Kim

  • Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

    Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron

  • The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

    Andrew N. Macintyre;Valerie A. Gerriets;Amanda G. Nichols;Ryan D. Michalek

  • PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

    Teresa C Leone;John J Lehman;Brian N Finck;Paul J Schaeffer

  • Cardiac metabolism in heart failure: implications beyond ATP production.

    Torsten Doenst;Tien Dung Nguyen;E. Dale Abel

  • Diabetic cardiomyopathy, causes and effects

    Sihem Boudina;Evan Dale Abel

  • Molecular mechanisms of diabetic cardiomyopathy.

    Heiko Bugger;E. Dale Abel

  • Cardiac Remodeling in Obesity

    E. Dale Abel;Sheldon E. Litwin;Gary Sweeney

  • GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

    Ethan A Winkler;Ethan A Winkler;Yoichiro Nishida;Yoichiro Nishida;Abhay P Sagare;Sanket V Rege

  • Mitochondrial Energetics in the Heart in Obesity-Related Diabetes: Direct Evidence for Increased Uncoupled Respiration and Activation of Uncoupling Proteins

    Sihem Boudina;Sandra Sena;Heather Theobald;Xiaoming Sheng

  • Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

    Jonathan Buchanan;Pradip K. Mazumder;Ping Hu;Gopa Chakrabarti

  • Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

    Samuel A. J. Trammell;Mark S. Schmidt;Benjamin J. Weidemann;Philip Redpath

  • Reduced Mitochondrial Oxidative Capacity and Increased Mitochondrial Uncoupling Impair Myocardial Energetics in Obesity

    Sihem Boudina;Sandra Sena;Brian T. O’Neill;Prakash Tathireddy

  • Heart Failure in Type 2 Diabetes Mellitus.

    Helena C. Kenny;E. Dale Abel

  • Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells

    Alfredo Caro-Maldonado;Ruoning Wang;Amanda G. Nichols;Masayuki Kuraoka

  • Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

    Pradip K. Mazumder;Brian T. O’Neill;Matthew W. Roberts;Jonathan Buchanan

  • Cardiac Energy Metabolism in Heart Failure

    Gary D. Lopaschuk;Qutuba G. Karwi;Rong Tian;Adam R. Wende

  • Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

    Darrell D. Belke;Sandrine Betuing;Martin J. Tuttle;Christophe Graveleau

  • Basic Mechanisms of Diabetic Heart Disease

    Rebecca H. Ritchie;E. Dale Abel

Frequent Co-Authors

Donald A. McClain
Donald A. McClain Wake Forest University
Jared Rutter
Jared Rutter University of Utah
Jeffrey C. Rathmell
Jeffrey C. Rathmell Vanderbilt University Medical Center
Andrew S. Weyrich
Andrew S. Weyrich University of Utah
John R. Hoidal
John R. Hoidal University of Utah
Neal S. Peachey
Neal S. Peachey Cleveland Clinic
James C. Cox
James C. Cox Georgia State University
Martin E. Young
Martin E. Young University of Alabama at Birmingham
William L. Holland
William L. Holland University of Utah
Li Wang
Li Wang Yale University

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