His scientific interests lie mostly in Internal medicine, Endocrinology, Mitochondrion, Diabetes mellitus and Glucose transporter. His Internal medicine study often links to related topics such as Thyroid hormone receptor beta. Endocrinology is a component of his Insulin resistance, Insulin, Insulin receptor, Adipose tissue and Beta oxidation studies.
His research in Mitochondrion intersects with topics in Steatosis, Signal transduction, Oxidative phosphorylation and Adenosine triphosphate. His Diabetes mellitus research is multidisciplinary, relying on both Diabetic cardiomyopathy, Cardiac dysfunction, Disease and Cardiology. In his work, Glycolysis is strongly intertwined with Glucose uptake, which is a subfield of Glucose transporter.
E. Dale Abel focuses on Internal medicine, Endocrinology, Cell biology, Mitochondrion and Insulin. His research integrates issues of Diabetes mellitus and Cardiology in his study of Internal medicine. His study explores the link between Endocrinology and topics such as Protein kinase B that cross with problems in PI3K/AKT/mTOR pathway.
As a part of the same scientific family, he mostly works in the field of Cell biology, focusing on Glycolysis and, on occasion, Beta oxidation. His Mitochondrion research is multidisciplinary, incorporating elements of Oxidative stress, Oxidative phosphorylation and Reactive oxygen species. The study incorporates disciplines such as Metabolic syndrome, Type 2 diabetes and Skeletal muscle in addition to Insulin resistance.
His main research concerns Internal medicine, Cell biology, Endocrinology, GLUT1 and Mitochondrion. His work deals with themes such as Signal transduction and Optic Atrophy 1, which intersect with Internal medicine. His Cell biology study combines topics in areas such as Glycolysis, Metabolism, Carbohydrate metabolism and Knockout mouse.
The various areas that E. Dale Abel examines in his Endocrinology study include Protein kinase B and PI3K/AKT/mTOR pathway. His GLUT1 research incorporates elements of Retinal pigment epithelium and Cancer research, Angiogenesis. His Mitochondrion research integrates issues from Reactive oxygen species, AMPK, Protein kinase A and Diabetic cardiomyopathy.
His primary areas of investigation include Endocrinology, Internal medicine, Cell biology, GLUT1 and Glucose transporter. E. Dale Abel has included themes like Signal transduction and Mitochondrion in his Endocrinology study. His biological study focuses on Insulin receptor.
His Cell biology course of study focuses on Glycolysis and Oxidative phosphorylation, Proinflammatory cytokine, Heart metabolism and Glycogen. His studies in GLUT1 integrate themes in fields like Psoriasis, Retinal pigment epithelium, Retina, Photoreceptor cell and Downregulation and upregulation. His Glucose transporter research includes elements of Cartilage and Endochondral ossification.
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Diabetic Cardiomyopathy Revisited
Sihem Boudina;E. Dale Abel.
Circulation (2007)
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
E Dale Abel;Odile Peroni;Jason K. Kim;Young Bum Kim.
Nature (2001)
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
Teresa C Leone;John J Lehman;Brian N Finck;Paul J Schaeffer.
PLOS Biology (2005)
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron.
Cell (2015)
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.
Zisman A;Peroni Od;Abel Ed;Michael.
Nature Medicine (2000)
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.
Andrew N. Macintyre;Valerie A. Gerriets;Amanda G. Nichols;Ryan D. Michalek.
Cell Metabolism (2014)
Cardiac Remodeling in Obesity
E. Dale Abel;Sheldon E. Litwin;Gary Sweeney.
Physiological Reviews (2008)
Cardiac metabolism in heart failure: implications beyond ATP production.
Torsten Doenst;Tien Dung Nguyen;E. Dale Abel.
Circulation Research (2013)
Molecular mechanisms of diabetic cardiomyopathy.
Heiko Bugger;E. Dale Abel.
Diabetologia (2014)
Mitochondrial Energetics in the Heart in Obesity-Related Diabetes: Direct Evidence for Increased Uncoupled Respiration and Activation of Uncoupling Proteins
Sihem Boudina;Sandra Sena;Heather Theobald;Xiaoming Sheng.
Diabetes (2007)
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