D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 42 Citations 15,011 79 World Ranking 14809 National Ranking 6193

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Biochemistry
  • Metabolism

His primary areas of study are Ceramide, Internal medicine, Endocrinology, Sphingolipid and Insulin resistance. Scott A. Summers combines subjects such as Lipid signaling, Insulin and Cell biology with his study of Ceramide. The various areas that Scott A. Summers examines in his Lipid signaling study include Protein kinase B and Akt/PKB signaling pathway.

His work on AMPK as part of general Cell biology research is frequently linked to Ceramidase activity, bridging the gap between disciplines. He is studying Receptor, which is a component of Internal medicine. He has included themes like Proinflammatory cytokine, Diabetes mellitus, Type 2 Diabetes Mellitus and Lipotoxicity in his Sphingolipid study.

His most cited work include:

  • Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation (1139 citations)
  • Inhibition of Ceramide Synthesis Ameliorates Glucocorticoid-, Saturated-Fat-, and Obesity-Induced Insulin Resistance (885 citations)
  • Ceramides in insulin resistance and lipotoxicity. (635 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Ceramide, Sphingolipid and Insulin resistance. His Steatosis, Glucose homeostasis and White adipose tissue study, which is part of a larger body of work in Internal medicine, is frequently linked to Downregulation and upregulation, bridging the gap between disciplines. In his study, which falls under the umbrella issue of Endocrinology, Dihydroceramide desaturase and Glycogen synthase is strongly linked to Protein kinase B.

Scott A. Summers has researched Ceramide in several fields, including Inflammation, Proinflammatory cytokine, Lipid signaling, Adiponectin and Programmed cell death. His Sphingolipid research is multidisciplinary, incorporating elements of Diabetes mellitus, Dyslipidemia, Type 2 Diabetes Mellitus and Cholesterol. His work deals with themes such as Steatohepatitis, Metabolic syndrome and Skeletal muscle, which intersect with Insulin resistance.

He most often published in these fields:

  • Internal medicine (68.79%)
  • Endocrinology (65.96%)
  • Ceramide (53.19%)

What were the highlights of his more recent work (between 2018-2021)?

  • Ceramide (53.19%)
  • Internal medicine (68.79%)
  • Endocrinology (65.96%)

In recent papers he was focusing on the following fields of study:

Scott A. Summers mainly focuses on Ceramide, Internal medicine, Endocrinology, Sphingolipid and Diabetes mellitus. His Ceramide research includes themes of Homeostasis, Coronary artery disease, Inflammation, Insulin resistance and Steatohepatitis. The Insulin resistance study combines topics in areas such as Adipose tissue, Steatosis, Dyslipidemia and Skeletal muscle.

His Sphingolipid research is multidisciplinary, incorporating perspectives in Serine C-palmitoyltransferase, Progenitor cell and Fatty acid. Scott A. Summers interconnects Heart disease and Bioinformatics in the investigation of issues within Diabetes mellitus. His studies deal with areas such as Leptin and White adipose tissue as well as Insulin.

Between 2018 and 2021, his most popular works were:

  • Targeting a ceramide double bond improves insulin resistance and hepatic steatosis. (93 citations)
  • Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease (34 citations)
  • Metabolic Messengers: ceramides. (23 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Metabolism
  • Diabetes mellitus

Scott A. Summers spends much of his time researching Ceramide, Diabetes mellitus, Sphingolipid, Coronary artery disease and Heart disease. His Sphingolipid research incorporates themes from Internal medicine, Endocrinology and Insulin resistance. In the subject of general Insulin resistance, his work in Lipotoxicity is often linked to Leptin Deficiency, thereby combining diverse domains of study.

His studies in Coronary artery disease integrate themes in fields like Cardiovascular health, MEDLINE and Intensive care medicine. He focuses mostly in the field of Heart disease, narrowing it down to topics relating to Calcium signaling and, in certain cases, Metabolism. The study incorporates disciplines such as Mitochondrion and Cell biology in addition to Glycolysis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

Aimee D. Kohn;Scott A. Summers;Morris J. Birnbaum;Richard A. Roth.
Journal of Biological Chemistry (1996)

1545 Citations

Inhibition of Ceramide Synthesis Ameliorates Glucocorticoid-, Saturated-Fat-, and Obesity-Induced Insulin Resistance

William L. Holland;Joseph T. Brozinick;Li Ping Wang;Eric D. Hawkins.
Cell Metabolism (2007)

1115 Citations

Ceramides in insulin resistance and lipotoxicity.

Scott A Summers.
Progress in Lipid Research (2006)

873 Citations

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

William L. Holland;Russell A. Miller;Zhao V. Wang;Kai Sun.
Nature Medicine (2011)

792 Citations

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids.

Jose Antonio Chavez;Trina A. Knotts;Li-Ping Wang;Guibin Li.
Journal of Biological Chemistry (2003)

638 Citations

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

William L. Holland;Benjamin T. Bikman;Li Ping Wang;Guan Yuguang.
Journal of Clinical Investigation (2011)

626 Citations

Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism

William L. Holland;Scott A. Summers.
Endocrine Reviews (2008)

512 Citations

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes.

Jose Antonio Chavez;Scott A Summers.
Archives of Biochemistry and Biophysics (2003)

510 Citations

A Ceramide-Centric View of Insulin Resistance

Jose A. Chavez;Scott A. Summers;Scott A. Summers.
Cell Metabolism (2012)

506 Citations

Regulation of Insulin-Stimulated Glucose Transporter GLUT4 Translocation and Akt Kinase Activity by Ceramide

Scott A. Summers;Luis A. Garza;Honglin Zhou;Morris J. Birnbaum.
Molecular and Cellular Biology (1998)

485 Citations

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