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D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
15865
World Ranking
12365
National Ranking
5293

Overview

Jared Rutter is affiliated with the University of Utah in the United States and focuses on research primarily in biochemistry, genetics, and molecular biology, with a significant emphasis on medicine. Their scholarly work spans several subfields, including molecular biology, cancer research, physiology, clinical biochemistry, and cardiology and cardiovascular medicine.

The key topics in Jared Rutter's research involve mitochondrial function and pathology, cancer, hypoxia, and metabolism, metabolism and genetic disorders, adipose tissue and metabolism, biochemical acid research studies, cardiovascular function and risk factors, and ATP synthase and ATPases research.

Jared Rutter has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, JCI Insight, Journal of Biological Chemistry, and Cell Metabolism. Among their recent papers are the following:

  • The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure (2020, Cell Metabolism)
  • Metabolites as signalling molecules (2023, Nature Reviews Molecular Cell Biology)
  • Mitochondrial pyruvate carriers are required for myocardial stress adaptation (2020, Nature Metabolism)
  • Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria (2020, eLife)
  • Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase (2023, Science)

Their research collaborations include frequent co-authorship with Ahmad A. Cluntun, James E. Cox, Alex J. Bott, Jordan A. Berg, and Gregory S. Ducker.

Best Publications

  • Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors.

    Jared Rutter;Martin Reick;Leeju C. Wu;Steven L. McKnight

  • A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.

    Daniel K. Bricker;Eric B. Taylor;John C. Schell;Thomas Orsak

  • SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma

    Huai Xiang Hao;Oleh Khalimonchuk;Margit Schraders;Noah Dephoure

  • Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport

    Chendong Yang;Bookyung Ko;Christopher T. Hensley;Lei Jiang

  • NPAS2: A Gas-Responsive Transcription Factor

    Elhadji M. Dioum;Jared Rutter;Jason R. Tuckerman;Gonzalo Gonzalez

  • Succinate dehydrogenase - Assembly, regulation and role in human disease.

    Jared Rutter;Dennis R. Winge;Joshua D. Schiffman

  • Metabolism and the control of circadian rhythms

    Jared Rutter;Martin Reick;Steven L. McKnight

  • A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth.

    John C. Schell;Kristofor A. Olson;Lei Jiang;Amy J. Hawkins

  • Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases

    Kelly J. Beumer;Jonathan K. Trautman;Ana Bozas;Ji Long Liu

  • Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.

    Bhagirath Chaurasia;Trevor S. Tippetts;Rafael Mayoral Monibas;Jinqi Liu

  • A Stress-Responsive System for Mitochondrial Protein Degradation

    Jin Mi Heo;Nurit Livnat-Levanon;Eric B. Taylor;Kevin T. Jones

  • Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.

    John C. Schell;Dona R. Wisidagama;Claire Bensard;Helong Zhao

  • Impaired cued and contextual memory in NPAS2-deficient mice

    Joseph A. Garcia;Di Zhang;Sandi Jo Estill;Carolyn Michnoff

  • Lactate dehydrogenase activity drives hair follicle stem cell activation

    Aimee Flores;John Schell;Abigail S. Krall;David Jelinek

  • Identification of a Protein Mediating Respiratory Supercomplex Stability

    Yu Chan Chen;Eric B. Taylor;Noah Dephoure;Jin Mi Heo

  • Hepatic Mitochondrial Pyruvate Carrier 1 is Required for Efficient Regulation of Gluconeogenesis and Whole-body Glucose Homeostasis

    Lawrence R. Gray;Mst Rasheda Sultana;Adam J. Rauckhorst;Lalita Oonthonpan

  • Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis

    Judith Simcox;Gisela Geoghegan;John Alan Maschek;Claire L. Bensard

  • Mitochondrial quality control by the ubiquitin–proteasome system

    Eric B. Taylor;Jared Rutter

  • Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins.

    Yu Chan Chen;George K.E. Umanah;Noah Dephoure;Shaida A. Andrabi

  • Hallmarks of a new era in mitochondrial biochemistry

    David J. Pagliarini;Jared Rutter

Frequent Co-Authors

Steven P. Gygi
Steven P. Gygi Harvard University
Dennis R. Winge
Dennis R. Winge University of Utah
Ralph J. DeBerardinis
Ralph J. DeBerardinis The University of Texas Southwestern Medical Center
E. Dale Abel
E. Dale Abel University of California, Los Angeles
Noah Dephoure
Noah Dephoure Cornell University
Eric B. Taylor
Eric B. Taylor University of British Columbia
William L. Holland
William L. Holland University of Utah
Scott A. Summers
Scott A. Summers University of Utah
Guy A. Rutter
Guy A. Rutter Imperial College London
Carl S. Thummel
Carl S. Thummel University of Utah

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