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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
14889
World Ranking
11259
National Ranking
865

Overview

Jon Frampton is affiliated with the University of Birmingham in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with focused subfields including Molecular Biology, Hematology, Genetics, Infectious Diseases, and Organic Chemistry.

Their work addresses topics such as Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, Tuberculosis Research and Epidemiology, Protein Degradation and Inhibitors, Chromosomal and Genetic Variations, RNA Research and Splicing, and Myeloproliferative Neoplasms: Diagnosis and Treatment.

Among recent publications, notable papers include:

  • Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells, 2021, published in Nucleic Acids Research
  • High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia, 2020, Scientific Reports
  • MYB insufficiency disrupts proteostasis in hematopoietic stem cells, leading to age-related neoplasia, 2023, Blood
  • PDGFRα/Sca-1 Sorted Mesenchymal Stromal Cells Reduce Liver Injury in Murine Models of Hepatic Ischemia-Reperfusion Injury, 2022, Stem Cells
  • Azetidines Kill Multidrug-Resistant Mycobacterium tuberculosis without Detectable Resistance by Blocking Mycolate Assembly, 2024, Journal of Medicinal Chemistry

Frequent coauthors collaborating with Jon Frampton include Mary L. Clarke, Carl Ward, Giacomo Volpe, Miguel A. Esteban, and Odd S. Gabrielsen.

Publications are often found in venues such as bioRxiv (Cold Spring Harbor Laboratory), Bone Reports, Scientific Reports, Advances in Experimental Medicine and Biology, and Nucleic Acids Research. The bioRxiv preprint server and Bone Reports are particularly frequent venues for this scientist's work.

Best Publications

  • A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

    Christian Schulz;Elisa Gomez Perdiguero;Laurent Chorro;Heather Szabo-Rogers

  • The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA.

    I Chambers;J Frampton;P Goldfarb;N Affara

  • Platelets secrete stromal cell–derived factor 1α and recruit bone marrow–derived progenitor cells to arterial thrombi in vivo

    Steffen Massberg;Ildiko Konrad;Katrin Schürzinger;Michael Lorenz

  • GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts.

    H Kulessa;J Frampton;T Graf

  • MafB Is an Interaction Partner and Repressor of Ets-1 That Inhibits Erythroid Differentiation

    Michael H Sieweke;Hildegard Tekotte;Jonathan Frampton;Thomas Graf

  • Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c‐Myb

    Nikla Emambokus;Nikla Emambokus;Alexandros Vegiopoulos;Alexandros Vegiopoulos;Ben Harman;Eric Jenkinson

  • Integrin α2β1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCγ2

    Osamu Inoue;Katsue Suzuki-Inoue;William L. Dean;Jon Frampton

  • Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

    Stanislav Rybtsov;Malgorzata Sobiesiak;Samir Taoudi;Céline Souilhol

  • Yolk sac macrophage progenitors traffic to the embryo during defined stages of development.

    C Stremmel;R Schuchert;F Wagner;R Thaler

  • Platelets contribute to postnatal occlusion of the ductus arteriosus

    Katrin Echtler;Konstantin Stark;Michael Lorenz;Sandra Kerstan

  • Fibrin activates GPVI in human and mouse platelets

    Osama M Alshehri;Craig E Hughes;Samantha Montague;Stephanie K Watson

  • Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the α globin cluster

    Jonathan Flint;Cristina Tufarelli;John Peden;Kevin Clark

  • A Comprehensive Proteomics and Genomics Analysis Reveals Novel Transmembrane Proteins in Human Platelets and Mouse Megakaryocytes Including G6b-B, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif Protein

    Yotis A. Senis;Michael G. Tomlinson;Ángel García;Stephanie Dumon

  • Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

    Gemma Swiers;Claudia Baumann;John O'Rourke;Eleni Giannoulatou

  • v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells.

    J Frampton;T Ramqvist;T Graf

  • Platelet adhesion via glycoprotein IIb integrin is critical for atheroprogression and focal cerebral ischemia : An in vivo study in mice lacking glycoprotein IIb

    Steffen Massberg;Katrin Schürzinger;Michael Lorenz;Ildiko Konrad

  • c-Myb is an essential downstream target for homeobox mediated transformation of hematopoietic cells

    Jay L. Hess;Claudia B. Bittner;Deniz T. Zeisig;Christian Bach

  • Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene

    Martino Introna;Josée Golay;Jon Frampton;Toru Nakano

  • Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility

    D Hacking;D Hacking;J C Knight;K Rockett;H Brown

  • The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters.

    Xichen Bao;Haitao Wu;Xihua Zhu;Xihua Zhu;Xiangpeng Guo;Xiangpeng Guo

Frequent Co-Authors

Steve P. Watson
Steve P. Watson University of Birmingham
Thomas Graf
Thomas Graf Centre for Genomic Regulation
Robert G. Ramsay
Robert G. Ramsay Peter MacCallum Cancer Centre
Steffen Massberg
Steffen Massberg Ludwig-Maximilians-Universität München
Hamid Dehghani
Hamid Dehghani University of Birmingham
Frederic Geissmann
Frederic Geissmann Memorial Sloan Kettering Cancer Center
Ian Chambers
Ian Chambers University of Edinburgh
Miguel A. Esteban
Miguel A. Esteban Guangzhou Institutes of Biomedicine and Health
Kay F. Macleod
Kay F. Macleod University of Chicago
Mark J. Walker
Mark J. Walker University of Queensland

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