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Biology and Biochemistry

D-Index
48
Citations
49380
World Ranking
18162
National Ranking
7420

Overview

Kay F. Macleod is a researcher affiliated with the University of Chicago in the United States. Their scholarly work spans across the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a total of 31 and 24 publications in these areas respectively.

The scientist's research delves deeply into molecular and cellular processes with a focus on topics such as Autophagy in Disease and Therapy, Endoplasmic Reticulum Stress and Disease, Pancreatic and Hepatic Oncology Research, Cancer, Hypoxia, and Metabolism, Ubiquitin and proteasome pathways, Pancreatic function and diabetes, and RNA modifications and cancer.

Kay F. Macleod has contributed to numerous publications, including several recent papers. Key publications include:

  • Autophagy in major human diseases, 2021, The EMBO Journal
  • Mitophagy in tumorigenesis and metastasis, 2021, Cellular and Molecular Life Sciences
  • ULK1 promotes mitophagy via phosphorylation and stabilization of BNIP3, 2021, Scientific Reports
  • Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis, 2023, eLife
  • BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver, 2021, Autophagy

Their frequent coauthors include Damián E. Berardi, Althea Bock-Hughes, Patrick B. Jonker, Colin Sheehan, and Alexander Muir, with multiple collaborations recorded among these colleagues.

Kay F. Macleod's research is often published in specialized scientific venues. Frequent publication locations are:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • The EMBO Journal
  • Cellular and Molecular Life Sciences

The scientist's subfields of study emphasize Molecular Biology, Epidemiology, Cancer Research, Cell Biology, and Oncology. This range reflects a comprehensive engagement with both fundamental biological mechanisms and clinical aspects of disease research, especially cancer.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Autophagy: cellular and molecular mechanisms.

    Danielle Glick;Sandra Barth;Kay F. Macleod

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

    Kay F. Macleod;Nicole Sherry;Greg Hannon;David Beach

  • Autophagy: assays and artifacts

    Sandra Barth;Danielle Glick;Kay F Macleod

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mitochondrial Dysfunction in Cancer

    Michelle L Boland;Aparajita H Chourasia;Kay F Macleod

  • Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system.

    K. F. Macleod;Y. Hu;T. Jacks

  • Mutation of E2f-1 Suppresses Apoptosis and Inappropriate S Phase Entry and Extends Survival of Rb-Deficient Mouse Embryos

    Kenneth Y Tsai;Yanwen Hu;Kay F Macleod;Denise Crowley;Denise Crowley

  • BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.

    Kristin Tracy;Benjamin C. Dibling;Benjamin T. Spike;James R. Knabb

  • Autophagy in cancer metastasis.

    E E Mowers;M N Sharifi;K F Macleod

  • The ets gene family.

    Kay Macleod;Dominique Leprince;Dominique Stehelin

  • Autophagy, cancer stem cells and drug resistance.

    Alexandra G Smith;Kay F Macleod

  • Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

    Thomas De Raedt;Zandra Walton;Jessica L. Yecies;Danan Li

  • Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3.

    Marina N. Sharifi;Erin E. Mowers;Lauren E. Drake;Chris Collier

  • Mitophagy and cancer

    Aparajita H Chourasia;Michelle L Boland;Kay F Macleod

  • Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis

    Aparajita H Chourasia;Kristin Tracy;Casey Frankenberger;Michelle L Boland

Frequent Co-Authors

Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Sergio Lavandero
Sergio Lavandero University of Chile
Nektarios Tavernarakis
Nektarios Tavernarakis Foundation for Research and Technology Hellas
Augustine M. K. Choi
Augustine M. K. Choi Cornell University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Francesco Cecconi
Francesco Cecconi Catholic University of the Sacred Heart
Mark J. Walker
Mark J. Walker University of Queensland
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute

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