Frank Essmann

Overview

Best Publications

• T-helper-1-cell cytokines drive cancer into senescence

  Heidi Braumüller;Thomas Wieder;Ellen Brenner;Sonja Aßmann

  834
  Citations

• Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

  Susanne Feil;Birgit Fehrenbacher;Robert Lukowski;Frank Essmann

  625
  Citations

• Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

  Thomas Wieder;Frank Essmann;Frank Essmann;Frank Essmann;Aram Prokop;Aram Prokop;Aram Prokop;Karin Schmelz;Karin Schmelz;Karin Schmelz

  326
  Citations

• Direct impact of cisplatin on mitochondria induces ROS production that dictates cell fate of ovarian cancer cells

  Markus Kleih;Kathrin Böpple;Meng Dong;Andrea Gaißler

  309
  Citations

• Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts

  T Wieder;A Prokop;B Bagci;F Essmann

  239
  Citations

• Apoptosis induction by different local anaesthetics in a neuroblastoma cell line

  R. Werdehausen;S. Fazeli;S. Braun;H. Hermanns

  237
  Citations

• Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo.

  A Prokop;T Wieder;I Sturm;F Essmann

  236
  Citations

• Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

  Clarissa von Haefen;Thomas Wieder;Frank Essmann;Klaus Schulze-Osthoff

  218
  Citations

• SOX2 expression associates with stem cell state in human ovarian carcinoma

  Petra M Bareiss;Anna Paczulla;Hui Wang;Rebekka Schairer

  167
  Citations

• Lidocaine induces apoptosis via the mitochondrial pathway independently of death receptor signaling.

  Robert Werdehausen;Sebastian Braun;Frank Essmann;Klaus Schulze-Osthoff

  165
  Citations

• Apoptin, a tumor-selective killer

  Marek Jan Los;Soumya Panigrahi;Iran Rashedi;Sanat Mandal

  162
  Citations

• Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event

  Frank Essmann;Ingo H. Engels;Gudrun Totzke;Klaus Schulze-Osthoff

  155
  Citations

• Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation.

  F Essmann;H Bantel;H Bantel;G Totzke;I H Engels;I H Engels

  154
  Citations

• A Novel Member of the IκB Family, Human IκB-ζ, Inhibits Transactivation of p65 and Its DNA Binding

  Gudrun Totzke;Frank Essmann;Stephan Pohlmann;Charlotte Lindenblatt

  145
  Citations

• Human Skin Endothelial Cells Can Express All 10 TLR Genes and Respond to Respective Ligands

  Nicole Fitzner;Sigrid Clauberg;Frank Essmann;Joerg Liebmann

  145
  Citations

• Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.

  E Keil;R Höcker;M Schuster;F Essmann

  144
  Citations

• p21 Blocks Irradiation-Induced Apoptosis Downstream of Mitochondria by Inhibition of Cyclin-Dependent Kinase–Mediated Caspase-9 Activation

  Dennis Sohn;Frank Essmann;Klaus Schulze-Osthoff;Reiner U. Jänicke

  142
  Citations

• Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.

  Bernhard Gillissen;Frank Essmann;Frank Essmann;Vilma Graupner;Lilian Stärck

  141
  Citations

• The multiple battles fought by anti-apoptotic p21.

  Reiner U Jänicke;Dennis Sohn;Frank Essmann;Klaus Schulze-Osthoff

  133
  Citations

• Pifithrin- α protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53

  D Sohn;V Graupner;V Graupner;D Neise;F Essmann

  126
  Citations