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Biology and Biochemistry

D-Index
72
Citations
14756
World Ranking
6446
National Ranking
455

Overview

Peter T. Daniel is a researcher affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their work spans several areas within medicine and molecular biology, with a particular focus on oncology and biochemical pathways related to cancer.

The main fields of study for Peter T. Daniel include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their research delves into specific subfields such as:

  • Oncology
  • Molecular Biology

The principal topics covered in their research are:

  • Cancer-related Molecular Pathways
  • Pancreatic and Hepatic Oncology Research
  • RNA modifications and cancer

Peter T. Daniel has authored publications that have appeared in recognized scientific journals. Their recent work includes the following paper:

  • "Withdrawal: p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity," published in 2023 in the Journal of Biological Chemistry.

This publication is associated with a network of frequent co-authors who have collaborated on research projects, including:

  • Guillaume Normand
  • Philipp Hemmati
  • Berlinda Verdoodt
  • Clarissa von Haefen
  • Jana Wendt

Peter T. Daniel's contributions are mainly disseminated through the Journal of Biological Chemistry, which serves as a primary venue for their research dissemination.

Best Publications

  • A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes.

    Anja Löffler;Peter Kufer;Peter Kufer;Peter Kufer;Ralf Lutterbüse;Ralf Lutterbüse;Ralf Lutterbüse;Florian Zettl;Florian Zettl;Florian Zettl

  • The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis.

    Monika Raisova;Amir M. Hossini;Jiirgen Eberle;Christian Riebeling

  • Regulation of apoptosis in the immune system.

    Peter H. Krammer;Iris Behrmann;Peter Daniel;Jens Dhein

  • Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens.

    Jens Dhein;Peter T. Daniel;Bernhard C. Trauth;Alex Oehm

  • Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis.

    Railf C. Bargou;Peter T. Daniel;Peter T. Daniel;Markus Y. Mapara;Markus Y. Mapara;Kurt Bommert

  • The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.

    A Banjac;T Perisic;H Sato;H Sato;A Seiler

  • Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

    Thomas Wieder;Frank Essmann;Frank Essmann;Frank Essmann;Aram Prokop;Aram Prokop;Aram Prokop;Karin Schmelz;Karin Schmelz;Karin Schmelz

  • The Role of APO-1-Mediated Apoptosis in the Immune System

    Peter H. Krammer;Jens Dhein;Henning Walczak;Iris Behrmann

  • The kiss of death: promises and failures of death receptors and ligands in cancer therapy.

    PT Daniel;T Wieder;I Sturm;I Sturm;K Schulze-Osthoff

  • Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.

    R C Bargou;C Wagener;K Bommert;M Y Mapara

  • Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

    Clarissa von Haefen;Thomas Wieder;Bernd Gillissen;Lilian Stärck

  • Activation induces sensitivity toward APO-1 (CD95)-mediated apoptosis in human B cells.

    Peter T. Daniel;Peter H. Krammer

  • Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts

    T Wieder;A Prokop;B Bagci;F Essmann

  • Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo.

    A Prokop;T Wieder;I Sturm;F Essmann

  • Analysis of the p53/BAX Pathway in Colorectal Cancer: Low BAX Is a Negative Prognostic Factor in Patients With Resected Liver Metastases

    Isrid Sturm;Claus-Henning Köhne;Gerhard Wolff;Henrik Petrowsky

  • Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

    Clarissa von Haefen;Thomas Wieder;Frank Essmann;Klaus Schulze-Osthoff

  • Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.

    Thorsten Stühmer;Manik Chatterjee;Martin Hildebrandt;Pia Herrmann

  • Dissecting the pathways to death.

    Daniel Pt

  • Guardians of cell death: the Bcl-2 family proteins

    Peter T Daniel;Klaus Schulze-Osthoff;Claus Belka;Dilek Güner

  • Association of Active Caspase 8 with the Mitochondrial Membrane during Apoptosis: Potential Roles in Cleaving BAP31 and Caspase 3 and Mediating Mitochondrion-Endoplasmic Reticulum Cross Talk in Etoposide-Induced Cell Death

    Dhyan Chandra;Grace Choy;Xiaodi Deng;Bobby Bhatia

Frequent Co-Authors

Bernd Dörken
Bernd Dörken Charité - University Medicine Berlin
Bernd Dörken
Bernd Dörken Charité - University Medicine Berlin
Klaus Schulze-Osthoff
Klaus Schulze-Osthoff University of Tübingen
Thomas Wieder
Thomas Wieder University of Tübingen
Frank Essmann
Frank Essmann University of Tübingen
Claus Belka
Claus Belka Ludwig-Maximilians-Universität München
Verena Jendrossek
Verena Jendrossek University of Duisburg-Essen
Martin Zeitz
Martin Zeitz Charité - University Medicine Berlin
Peter H. Krammer
Peter H. Krammer German Cancer Research Center
Thomas Blankenstein
Thomas Blankenstein Max Delbrück Center for Molecular Medicine

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