Marek Los

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Poland Leader Award
• 2025 - Research.com Biology and Biochemistry in Poland Leader Award
• 2023 - Research.com Biology and Biochemistry in Poland Leader Award
• 2022 - Research.com Biology and Biochemistry in Poland Leader Award
• 1994 - Perkin Medal, Society of Chemical Industry, American Section

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Apoptosis signaling by death receptors

  Klaus Schulze-Osthoff;Davide Ferrari;Marek Los;Sebastian Wesselborg

  1438
  Citations

• Autophagy and apoptosis dysfunction in neurodegenerative disorders.

  Saeid Ghavami;Shahla Shojaei;Behzad Yeganeh;Sudharsana R. Ande

  1096
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  895
  Citations

• Apoptosis and cancer: mutations within caspase genes

  Saeid Ghavami;Mohammad Hashemi;Sudharsana R Ande;Behzad Yeganeh

  885
  Citations

• Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

  Marek Los;Marek Los;Marc Van de Craen;Louis C. Penning;Heike Schenk

  815
  Citations

• PARP is important for genomic stability but dispensable in apoptosis

  Zhao-Qi Wang;Laura Stingl;Ciaran Morrison;Michael Jantsch

  749
  Citations

• Activation and Caspase-mediated Inhibition of PARP: A Molecular Switch between Fibroblast Necrosis and Apoptosis in Death Receptor Signaling

  Marek Los;Malgorzata Mozoluk;Davide Ferrari;Anna Stepczynska

  621
  Citations

• Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy.

  Subbareddy Maddika;Sudharsana Rao Ande;Soumya Panigrahi;Ted Paranjothy

  610
  Citations

• The Role of Caspases in Development, Immunity, and Apoptotic Signal Transduction: Lessons from Knockout Mice

  Marek Los;Sebastian Wesselborg;Klaus Schulze-Osthoff

  577
  Citations

• Cancer stem cell markers in common cancers – therapeutic implications

  Thomas Klonisch;Emilia Wiechec;Sabine Hombach-Klonisch;Sudharsana R. Ande

  504
  Citations

• Betulinic Acid Triggers CD95 (APO-1/Fas)- and p53-independent Apoptosis via Activation of Caspases in Neuroectodermal Tumors

  Simone Fulda;Claudia Friesen;Marek Los;Carsten Scaffidi

  486
  Citations

• HIV-1 Tat Potentiates TNF-induced NF-kappa B Activation and Cytotoxicity by Altering the Cellular Redox State

  Michael O. Westendorp;Vladimir A. Shatrov;Klaus Schulze-Osthoff;Rainer Frank

  467
  Citations

• IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase.

  Marek Jan Los;H. Schenk;K. Hexel;Pa Baeuerle

  429
  Citations

• Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.

  Sebastian Wesselborg;Ingo H. Engels;Evi Rossmann;Marek Los

  416
  Citations

• S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

  Saeid Ghavami;Iran Rashedi;Brian M. Dattilo;Mehdi Eshraghi

  389
  Citations

• Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes

  Klaus Schulze-Osthoff;Marek Los;Patrick A. Baeuerle

  371
  Citations

• Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer

  Wiem Chaabane;Sırma D User;Sırma D User;Mohamed El-Gazzah;Roman Jaksik

  362
  Citations

• P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death.

  Davide Ferrari;Marek Los;Manuel K.A. Bauer;Peter Vandenabeele

  357
  Citations

• Hydrogen peroxide as a potent activator of T lymphocyte functions.

  Marek Los;Wulf Dröge;Kirstin Stricker;Patrick A. Baeuerle

  317
  Citations