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Thomas Klonisch

Thomas Klonisch

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
10252
World Ranking
13357
National Ranking
459

Overview

Thomas Klonisch is affiliated with the University of Manitoba in Canada. Their research spans several fields within biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular biology and oncology.

Their notable papers include:

  • Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma (2022) published in International Journal of Molecular Sciences
  • Investigations on T cell transmigration in a human skin-on-chip (SoC) model (2021) published in Lab on a Chip
  • Novel CTRP8-RXFP1-JAK3-STAT3 axis promotes Cdc42-dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells (2021) published in Molecular Oncology
  • Genes of the Ubiquitin Proteasome System Qualify as Differential Markers in Malignant Glioma of Astrocytic and Oligodendroglial Origin (2022) published in Cellular and Molecular Neurobiology
  • Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling (2023) published in International Journal of Molecular Sciences

Frequent coauthors associated with Thomas Klonisch's work are:

  • Sabine Hombach-Klonisch (22 joint works)
  • Thatchawan Thanasupawat (17 joint works)
  • Aleksandra Głogowska (8 joint works)
  • Jason Beiko (5 joint works)
  • Jerry Vriend (5 joint works)

The key publication venues for their research include:

  • International Journal of Molecular Sciences (5 publications)
  • Biochemical Pharmacology (3 publications)
  • SSRN Electronic Journal (2 publications)
  • Endocrine Abstracts (2 publications)
  • Lab on a Chip (1 publication)

Thomas Klonisch's research focuses on several main fields:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, the identified subfields of study are:

  • Molecular Biology
  • Oncology
  • Immunology
  • Biomedical Engineering
  • Public Health, Environmental and Occupational Health

The main research topics covered in their publications include:

  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors
  • Pregnancy-related medical research
  • Histone Deacetylase Inhibitors Research
  • Epigenetics and DNA Methylation
  • 3D Printing in Biomedical Research
  • Brain Metastases and Treatment

Best Publications

  • Cancer stem cell markers in common cancers – therapeutic implications

    Thomas Klonisch;Emilia Wiechec;Sabine Hombach-Klonisch;Sudharsana R. Ande

  • Stimulation of monokine production by lipoteichoic acids.

    S Bhakdi;T Klonisch;P Nuber;W Fischer

  • S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3.

    Saeid Ghavami;Mehdi Eshragi;Sudharsana R Ande;Walter J Chazin

  • Interconnections between apoptotic, autophagic and necrotic pathways : implications for cancer therapy development

    Mayur V. Jain;Anna M. Paczulla;Thomas Klonisch;Florence N. Dimgba

  • Molecular interactions of the aryl hydrocarbon receptor and its biological and toxicological relevance for reproduction

    P Pocar;B Fischer;T Klonisch;S Hombach-Klonisch

  • Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response.

    Sabine Hombach-Klonisch;Maryam Mehrpour;Shahla Shojaei;Craig Harlos

  • Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway.

    Saeid Ghavami;Ahmad Asoodeh;Ahmad Asoodeh;Thomas Klonisch;Andrew J. Halayko

  • Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts.

    Saeid Ghavami;Rayan H. Cunnington;Shivika Gupta;Behzad Yeganeh

  • Expression of mRNA and protein of nucleoproteins during human spermiogenesis.

    Klaus Steger;Thomas Klonisch;Karsten Gavenis;Birgit Drabent

  • Expression of protamine-1 and -2 mRNA during human spermiogenesis

    Klaus Steger;Katharina Pauls;Thomas Klonisch;Folker E. Franke

  • New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets

    Pooneh Mokarram;Mohammed Albokashy;Maryam Zarghooni;Mohammad Amin Moosavi

  • Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts

    S Ghavami;B Yeganeh;G L Stelmack;H H Kashani

  • S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.

    Saeid Ghavami;Claus Kerkhoff;Walter J. Chazin;Kamran Kadkhoda

  • Round spermatids from infertile men exhibit decreased protamine-1 and -2 mRNA

    Klaus Steger;Klaus Failing;Thomas Klonisch;Hermann M. Behre

  • An investigation of the effects of endometriosis on the proteome of human eutopic endometrium: a heterogeneous tissue with a complex disease.

    Paul Alfred Francois Fowler;Jenny Tattum;Siladitya Bhattacharya;Thomas Klonisch

  • Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.

    Javad Alizadeh;Amir A. Zeki;Nima Mirzaei;Sandipan Tewary

  • Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts

    Saeid Ghavami;Saeid Ghavami;Behzad Yeganeh;Amir A. Zeki;Shahla Shojaei

  • Photodynamic N-TiO 2 Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells

    Mohammad Amin Moosavi;Maryam Sharifi;Soroush Moasses Ghafary;Soroush Moasses Ghafary;Zahra Mohammadalipour

  • Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53.

    Saeid Ghavami;Mark M Mutawe;Pawan Sharma;Behzad Yeganeh

  • Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes

    Shahla Shojaei;Navid Koleini;Ehsan Samiei;Mahmoud Aghaei;Mahmoud Aghaei

Frequent Co-Authors

Saeid Ghavami
Saeid Ghavami University of Manitoba
Andrew J. Halayko
Andrew J. Halayko University of Manitoba
Marek Los
Marek Los Silesian University of Technology
Henning Dralle
Henning Dralle University of Duisburg-Essen
Grant M. Hatch
Grant M. Hatch University of Manitoba
G. William Wong
G. William Wong Johns Hopkins University School of Medicine
Elissavet Kardami
Elissavet Kardami University of Manitoba
Klaus Schulze-Osthoff
Klaus Schulze-Osthoff University of Tübingen
Ibrahim M. Adham
Ibrahim M. Adham University of Göttingen
Mohsen Akbari
Mohsen Akbari University of Victoria

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