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D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
10878
World Ranking
15605
National Ranking
6509

Overview

G. William Wong is affiliated with the Johns Hopkins University School of Medicine in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Physiology, Molecular Biology, Epidemiology, Endocrinology, Diabetes and Metabolism, and Surgery.

The main topics covered in Wong's work include:

  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiovascular Disease and Adiposity
  • Pancreatic function and diabetes
  • Regulation of Appetite and Obesity
  • Physiological and biochemical adaptations
  • Metabolism, Diabetes, and Cancer

Wong has published extensively in several scientific venues. They have a notable presence in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • American Journal of Physiology-Endocrinology and Metabolism
  • The FASEB Journal
  • Molecular Metabolism

Among recent scholarly articles, Wong contributed to these notable papers:

  • Opportunities, barriers, and recommendations in Down syndrome research (2021), published in Translational Science of Rare Diseases
  • Obesity alters Ace2 and Tmprss2 expression in lung, trachea, and esophagus in a sex-dependent manner: Implications for COVID-19 (2020), published in Biochemical and Biophysical Research Communications
  • Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice (2021), published in Journal of Clinical Investigation
  • Loss of CTRP4 alters adiposity and food intake behaviors in obese mice (2020), published in American Journal of Physiology-Endocrinology and Metabolism
  • Androgen-induced insulin resistance is ameliorated by deletion of hepatic androgen receptor in females (2021), published in The FASEB Journal

Frequent collaborators in Wong's research include:

  • Dylan C. Sarver
  • Muzna Saqib
  • Fangluo Chen
  • Susan Aja
  • Susana Rodriguez

Best Publications

  • Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

    Suraj Peri;Suraj Peri;J. Daniel Navarro;J. Daniel Navarro;Ramars Amanchy;Troels Z. Kristiansen;Troels Z. Kristiansen

  • Heparin is essential for the storage of specific granule proteases in mast cells

    Donald E. Humphries;Guang W. Wong;Daniel S. Friend;Michael F. Gurish

  • A family of Acrp30/adiponectin structural and functional paralogs.

    Guang W. Wong;Jin Wang;Christopher Hug;Christopher Hug;Tsu Shuen Tsao

  • Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-γ agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions

    G. William Wong;Sarah A. Krawczyk;Claire Kitidis-Mitrokostas;Tracy Revett

  • Myonectin (CTRP15), a Novel Myokine That Links Skeletal Muscle to Systemic Lipid Homeostasis *

    Marcus M. Seldin;Jonathan M. Peterson;Mardi S. Byerly;Zhikui Wei

  • Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin

    G. William Wong;Sarah A. Krawczyk;Claire Kitidis-Mitrokostas;Guangtao Ge

  • C1q/TNF-related Protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output.

    Jonathan M. Peterson;Zhikui Wei;G. William Wong

  • Metabolic function of the CTRP family of hormones

    Marcus M. Seldin;Stefanie Y. Tan;G. William Wong

  • PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains

    Xinxin Gao;Pamela R. Lowry;Xin Zhou;Charlene Depry

  • C1q/TNF-Related Proteins, A Family of Novel Adipokines, Induce Vascular Relaxation Through the Adiponectin Receptor-1/AMPK/eNOS/Nitric Oxide Signaling Pathway

    Qijun Zheng;Yuexing Yuan;Wei Yi;Wei Yi;Wayne Bond Lau

  • CTRP1 Protein Enhances Fatty Acid Oxidation via AMP-activated Protein Kinase (AMPK) Activation and Acetyl-CoA Carboxylase (ACC) Inhibition *

    Jonathan M. Peterson;Susan Aja;Zhikui Wei;G. William Wong

  • C1q/TNF-related Protein-12 (CTRP12), a Novel Adipokine That Improves Insulin Sensitivity and Glycemic Control in Mouse Models of Obesity and Diabetes

    Zhikui Wei;Jonathan M. Peterson;Xia Lei;Liudmila Cebotaru

  • Metabolic Regulation by C1q/TNF-related Protein-13 (CTRP13) ACTIVATION OF AMP-ACTIVATED PROTEIN KINASE AND SUPPRESSION OF FATTY ACID-INDUCED JNK SIGNALING

    Zhikui Wei;Jonathan M. Peterson;G. William Wong

  • The Tryptase, Mouse Mast Cell Protease 7, Exhibits Anticoagulant Activity in Vivo and in Vitro Due to Its Ability to Degrade Fibrinogen in the Presence of the Diverse Array of Protease Inhibitors in Plasma

    Chifu Huang;Guang W. Wong;Namit Ghildyal;Michael F. Gurish

  • RasGRP4, a New Mast Cell-restricted Ras Guanine Nucleotide-releasing Protein with Calcium- and Diacylglycerol-binding Motifs IDENTIFICATION OF DEFECTIVE VARIANTS OF THIS SIGNALING PROTEIN IN ASTHMA, MASTOCYTOSIS, AND MAST CELL LEUKEMIA PATIENTS AND DEMONSTRATION OF THE IMPORTANCE OF RasGRP4 IN MAST CELL DEVELOPMENT AND FUNCTION

    Yi Yang;Lixin Li;Guang W. Wong;Steven A. Krilis

  • CTRP9 transgenic mice are protected from diet-induced obesity and metabolic dysfunction

    Jonathan M. Peterson;Zhikui Wei;Marcus M. Seldin;Mardi S. Byerly

  • CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism

    Jonathan M. Peterson;Marcus M. Seldin;Zhikui Wei;Susan Aja

  • Skeletal muscle-derived myonectin activates the mammalian target of rapamycin (mTOR) pathway to suppress autophagy in liver.

    Marcus M. Seldin;Xia Lei;Stefanie Y. Tan;Kevin P. Stanson

  • Dynamic Visualization of mTORC1 Activity in Living Cells

    Xin Zhou;Terri L. Clister;Pamela R. Lowry;Marcus M. Seldin

  • Mast cells/basophils in the peripheral blood of allergic individuals who are HIV-1 susceptible due to their surface expression of CD4 and the chemokine receptors CCR3, CCR5, and CXCR4

    Yong Li;Lixin Li;Robert Wadley;Stephen W. Reddel

Frequent Co-Authors

Richard L. Stevens
Richard L. Stevens Brigham and Women's Hospital
Seth Blackshaw
Seth Blackshaw Johns Hopkins University School of Medicine
Andrew E. Jaffe
Andrew E. Jaffe Johns Hopkins University
Thomas Klonisch
Thomas Klonisch University of Manitoba
Steven A. Krilis
Steven A. Krilis University of New South Wales
Akhilesh Pandey
Akhilesh Pandey Mayo Clinic
Nibaldo C. Inestrosa
Nibaldo C. Inestrosa Pontificia Universidad Católica de Chile
Timothy H. Moran
Timothy H. Moran Johns Hopkins University School of Medicine
Samer Hattar
Samer Hattar National Institutes of Health

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