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Immunology

D-Index
56
Citations
21359
World Ranking
3665
National Ranking
150

Overview

Steven A. Krilis is affiliated with the University of New South Wales in Australia and has contributed extensively to medical research, particularly in rheumatology and immunology.

Their research spans several fields of study including:

  • Medicine
  • Rheumatology
  • Hematology
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine
  • Immunology

Main topics addressed in their work include:

  • Systemic Lupus Erythematosus Research
  • Platelet Disorders and Treatments
  • Cell Adhesion Molecules Research
  • Vasculitis and related conditions
  • Atherosclerosis and Cardiovascular Diseases
  • Calpain Protease Function and Regulation
  • Lipoproteins and Cardiovascular Health

Steven A. Krilis has published multiple articles in known venues such as:

  • Journal of Autoimmunity
  • Annals of the Rheumatic Diseases
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Clinical Immunology

Notable recent papers include:

  • "2023 ACR/EULAR antiphospholipid syndrome classification criteria," 2023, Annals of the Rheumatic Diseases
  • "Free Thiol β2-GPI (β-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "Βeta-2-glycoprotein I exerts antithrombotic function through its domain V in mice," 2021, Journal of Autoimmunity
  • "Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk," 2021, Journal of Autoimmunity
  • "Domain 5 of Beta 2 glycoprotein I: Friend or foe in health? Context matters," 2024, Clinical Immunology

Frequent co-authors collaborating with Steven A. Krilis include:

  • Bill Giannakopoulos
  • Miao Qi
  • Medha Barbhaiya
  • Stéphane Zuily
  • Ray Naden

Best Publications

  • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).

    S. Miyakis;M. D. Lockshin;T. Atsumi;D. W. Branch

  • Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

    H P McNeil;R J Simpson;C N Chesterman;S A Krilis

  • The Pathogenesis of the Antiphospholipid Syndrome

    Bill Giannakopoulos;Steven A Krilis

  • Immunology and clinical importance of antiphospholipid antibodies.

    H P McNeil;C N Chesterman;S A Krilis

  • Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: Report of a Task Force at the 13th International Congress on Antiphospholipid Antibodies

    G. Ruiz-Irastorza;M. J. Cuadrado;I. Ruiz-Arruza;Robin L Brey

  • A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection.

    J E Hunt;H P McNeil;G J Morgan;R M Crameri

  • Current concepts on the pathogenesis of the antiphospholipid syndrome.

    Bill Giannakopoulos;Freda Passam;Soheila Rahgozar;Steven A. Krilis

  • Prevalence of lupus anticoagulant and anticardiolipin antibodies in a healthy population

    W. Shi;S. A. Krilis;B. H. Chong;S. Gordon

  • How we diagnose the antiphospholipid syndrome

    Bill Giannakopoulos;Freda Passam;Yiannis Ioannou;Steven A. Krilis

  • Identification of a region of beta 2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity.

    J E Hunt;R J Simpson;S A Krilis

  • Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka

    David Andresen;Annabelle Donaldson;Lennart Choo;Adrian Knox

  • Anticardiolipin antibodies and lupus anticoagulants comprise separate antibody subgroups with different phospholipid binding characteristics.

    H. Patrick McNeil;Colin N. Chesterman;Steven A. Krilis

  • Site-directed mutagenesis of recombinant human beta 2-glycoprotein I identifies a cluster of lysine residues that are critical for phospholipid binding and anti-cardiolipin antibody activity.

    Yonghua Sheng;Andrej Sali;Herbert Herzog;Jelle Lahnstein

  • Anti–β2‐glycoprotein I antibodies in complex with β2‐glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib‐IX‐V

    Tong Shi;B M Giannakopoulos;X Yan;Pei Yu

  • Coronary artery bypass graft failure--an autoimmune phenomenon?

    KarenE Morton;KarenE Morton;StevenA Krilis;StevenA Krilis;DavidW Baron;DavidW Baron;ThomasP Gavaghan;ThomasP Gavaghan

  • Beta 2 glycoprotein I--function in health and disease

    Spiros Miyakis;Bill Giannakopoulos;Steven A. Krilis

  • Development of Mast Cells and Importance of Their Tryptase and Chymase Serine Proteases in Inflammation and Wound Healing

    Jeffrey Douaiher;Julien Succar;Luca Lancerotto;Michael Fagersten Gurish

  • Use of Single Point Mutations in Domain I of β2-Glycoprotein I to Determine Fine Antigenic Specificity of Antiphospholipid Autoantibodies

    G. Michael Iverson;Stephen Reddel;Edward J. Victoria;Keith A. Cockerill

  • Human β2-Glycoprotein I Binds to Endothelial Cells Through a Cluster of Lysine Residues That Are Critical for Anionic Phospholipid Binding and Offers Epitopes for Anti-β2-Glycoprotein I Antibodies

    N. Del Papa;Y. H. Sheng;E. Raschi;D. A. Kandiah

  • Essential role for mast cell tryptase in acute experimental colitis

    Matthew J. Hamilton;Mark J. Sinnamon;Gregory D. Lyng;Jonathan N. Glickman

  • RasGRP4, a New Mast Cell-restricted Ras Guanine Nucleotide-releasing Protein with Calcium- and Diacylglycerol-binding Motifs IDENTIFICATION OF DEFECTIVE VARIANTS OF THIS SIGNALING PROTEIN IN ASTHMA, MASTOCYTOSIS, AND MAST CELL LEUKEMIA PATIENTS AND DEMONSTRATION OF THE IMPORTANCE OF RasGRP4 IN MAST CELL DEVELOPMENT AND FUNCTION

    Yi Yang;Lixin Li;Guang W. Wong;Steven A. Krilis

  • Pathogenic role of anti-beta 2-glycoprotein I antibodies in antiphospholipid associated fetal loss: characterisation of beta 2-glycoprotein I binding to trophoblast cells and functional effects of anti-beta 2-glycoprotein I antibodies in vitro.

    N. Di Simone;E. Raschi;C. Testoni;R. Castellani

  • Beta 2-glycoprotein I.

    David A. Kandiah;Steven A. Krilis

Frequent Co-Authors

Richard L. Stevens
Richard L. Stevens Brigham and Women's Hospital
Colin N. Chesterman
Colin N. Chesterman University of New South Wales
Brian A. Baldo
Brian A. Baldo University of Sydney
Antony Basten
Antony Basten Garvan Institute of Medical Research
Andrej Sali
Andrej Sali University of California, San Francisco
Takao Koike
Takao Koike Hokkaido University
E. J. Corey
E. J. Corey Harvard University
Robert A. Lewis
Robert A. Lewis University of California, San Francisco
Tatsuya Atsumi
Tatsuya Atsumi Hokkaido University
Angela Tincani
Angela Tincani University of Brescia

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