His main research concerns Immunology, Internal medicine, Endocrinology, Inflammation and Asthma. The various areas that he examines in his Immunology study include Respiratory disease, COPD, Histone deacetylase 2, Sputum and Histone. As a member of one scientific family, Ian M. Adcock mostly works in the field of Internal medicine, focusing on Messenger RNA and, on occasion, Gene expression, Nitric oxide synthase and Cell biology.
His Endocrinology study integrates concerns from other disciplines, such as Receptor and Intensive care. His research integrates issues of Biopsy and PI3K/AKT/mTOR pathway, Signal transduction in his study of Inflammation. The Exhaled nitric oxide research he does as part of his general Asthma study is frequently linked to other disciplines of science, such as Mechanism, therefore creating a link between diverse domains of science.
His primary areas of investigation include Immunology, Internal medicine, Asthma, COPD and Inflammation. His work carried out in the field of Immunology brings together such families of science as Sputum, Lung and Disease. His research investigates the connection with Internal medicine and areas like Endocrinology which intersect with concerns in Cytokine.
The study incorporates disciplines such as Respiratory disease, Phenotype, Intensive care medicine, Allergy and Corticosteroid in addition to Asthma. Ian M. Adcock interconnects Pulmonary disease and Bioinformatics in the investigation of issues within COPD. His studies deal with areas such as Oxidative stress and Pharmacology as well as Inflammation.
Ian M. Adcock mostly deals with Immunology, Asthma, Internal medicine, Sputum and COPD. He works mostly in the field of Immunology, limiting it down to topics relating to Respiratory system and, in certain cases, Exhaled nitric oxide. His Asthma research includes elements of Phenotype, Transcriptome, Allergy and Intensive care medicine.
His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology and Oncology. He combines subjects such as FURIN Gene, Inflammasome and Cohort with his study of Sputum. The COPD study combines topics in areas such as Airway and Lung.
Asthma, Immunology, Internal medicine, Immune system and Sputum are his primary areas of study. Ian M. Adcock has included themes like COPD, Allergy and Intensive care medicine in his Asthma study. His research in Immunology intersects with topics in Human virome and Respiratory system.
His research in the fields of Biomarker, vitamin D deficiency and Pulmonary disease overlaps with other disciplines such as In patient. His Immune system research integrates issues from Interleukin 33, Exacerbation, Phagocytosis and Degranulation. His Sputum research includes themes of FURIN Gene, Furin, Bronchial brushing and Proteases.
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International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Kian Fan Chung;Sally E. Wenzel;Jan L. Brozek;Andrew Bush.
European Respiratory Journal (2014)
Decreased Histone Deacetylase Activity in Chronic Obstructive Pulmonary Disease
Kazuhiro Ito;Misako Ito;W Mark Elliott;Borja Cosio.
The New England Journal of Medicine (2005)
Glucocorticoid resistance in inflammatory diseases
Peter J Barnes;Ian M Adcock.
The Lancet (2009)
Anti-inflammatory actions of steroids: molecular mechanisms
Peter J. Barnes;Ian Adcock;Michael Spedding;Paul M. Vanhoutte.
Trends in Pharmacological Sciences (1993)
Oxidative stress and redox regulation of lung inflammation in COPD
I. Rahman;I. M. Adcock.
European Respiratory Journal (2006)
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
Kazuhiro Ito;Peter J. Barnes;Ian M. Adcock.
Molecular and Cellular Biology (2000)
Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
Kazuhiro Ito;Satoshi Yamamura;Sarah Essilfie-Quaye;Borja Cosio.
Journal of Experimental Medicine (2006)
Histone acetylation and deacetylation: importance in inflammatory lung diseases
P. J. Barnes;I. M. Adcock;K. Ito.
European Respiratory Journal (2005)
Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction
K F Chung;I M Adcock.
European Respiratory Journal (2008)
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression
Kazuhiro Ito;Sam Lim;Gaetano Caramori;Borja Cosio.
Proceedings of the National Academy of Sciences of the United States of America (2002)
European Journal of Pharmacology
(Impact Factor: 5.195)
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