World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
9005
World Ranking
14074
National Ranking
491

Overview

Grant M. Hatch is affiliated with the University of Manitoba in Canada. Their research spans multiple disciplines, primarily within Medicine and Biochemistry, Genetics and Molecular Biology. Their work features a strong focus on molecular and cellular processes, with significant contributions to fields such as Molecular Biology, Immunology, Cardiology and Cardiovascular Medicine, Surgery, and Epidemiology.

Grant M. Hatch's publications concentrate on various scientific topics, including:

  • Mitochondrial Function and Pathology
  • Pancreatic function and diabetes
  • ATP Synthase and ATPases Research
  • Immune Cell Function and Interaction
  • Berberine and alkaloids research
  • Drug Transport and Resistance Mechanisms
  • Cannabis and Cannabinoid Research

The scientist's recent papers illustrate a diverse range of research interests and collaborative efforts. Selected recent works include:

  • Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia (2023) published in Immunity & Ageing
  • Barth syndrome: cardiolipin, cellular pathophysiology, management, and novel therapeutic targets (2021) published in Molecular and Cellular Biochemistry
  • Cardiolipin deficiency elevates susceptibility to a lipotoxic hypertrophic cardiomyopathy (2020) published in Journal of Molecular and Cellular Cardiology
  • Adiponectin deficiency induces hepatic steatosis during pregnancy and gestational diabetes in mice (2022) published in Diabetologia
  • Mitochondrial Respiration Correlates with Prognostic Markers in Chronic Lymphocytic Leukemia and Is Normalized by Ibrutinib Treatment (2020) published in Cancers

Frequent collaborators of Grant M. Hatch include:

  • Laura Cole
  • Vernon W. Dolinsky
  • Genevieve C. Sparagna
  • Hana M. Zegallai
  • Bo Xiang

Grant M. Hatch publishes regularly in specific venues, some of which serve as recurring platforms for their research dissemination. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular and Cellular Cardiology
  • Scientific Reports
  • The Journal of Immunology
  • The FASEB Journal

Their interdisciplinary approach bridges detailed molecular investigations with broader clinical and pathological contexts, notably involving cardiac, metabolic, and immune-related conditions. This integrative perspective informs ongoing work at the crossroads of cellular biology and disease processes.

Best Publications

  • Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells

    Ryan W. Mitchell;Ngoc H. On;Marc R. Del Bigio;Donald W. Miller

  • Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ.

    Yang Yu;Hongwei Du;Shengnan Wei;Linjing Feng

  • Host cell phospholipids are trafficked to and then modified by Chlamydia trachomatis.

    John L. Wylie;Grant M. Hatch;Grant Mcclarty

  • Activation of Raf/MEK/ERK/cPLA2 Signaling Pathway Is Essential for Chlamydial Acquisition of Host Glycerophospholipids

    Heng Su;Grant McClarty;Feng Dong;Grant M. Hatch

  • Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes

    Kyle G. Cheung;Laura K. Cole;Bo Xiang;Keyun Chen

  • Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARα in murine heart

    Biao Lu;Yan J. Jiang;Yaling Zhou;Fred Y. Xu

  • Fatty acid transport into the brain: of fatty acid fables and lipid tails.

    Ryan W. Mitchell;Grant M. Hatch

  • Cardiolipin metabolism and Barth Syndrome

    Kristin D. Hauff;Grant M. Hatch

  • Mitochondrial phospholipids: role in mitochondrial function

    Edgard M. Mejia;Grant M. Hatch

  • Stomatin-Like Protein 2 Binds Cardiolipin and Regulates Mitochondrial Biogenesis and Function

    Darah A. Christie;Caitlin D. Lemke;Isaac M. Elias;Luan A. Chau

  • Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies

    Wenguang Chang;Li Chen;Grant M. Hatch

  • Cell biology of cardiac mitochondrial phospholipids.

    Grant M Hatch

  • Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure

    Harjot K. Saini-Chohan;Michael G. Holmes;Adam J. Chicco;William A. Taylor

  • Oxidative modification of low density lipoprotein in normal and hyperlipidemic patients: effect of lysophosphatidylcholine composition on vascular relaxation.

    L. Chen;B. Liang;D. E. Froese;S. Liu

  • Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.

    Javad Alizadeh;Amir A. Zeki;Nima Mirzaei;Sandipan Tewary

  • Identification of the human mitochondrial linoleoyl-coenzyme A monolysocardiolipin acyltransferase (MLCL AT-1).

    William A. Taylor;Grant M. Hatch

  • Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes

    Shahla Shojaei;Navid Koleini;Ehsan Samiei;Mahmoud Aghaei;Mahmoud Aghaei

  • Berberine improves insulin resistance in cardiomyocytes via activation of 5'-adenosine monophosphate-activated protein kinase.

    Wenguang Chang;Ming Zhang;Jing Li;Zhaojie Meng

  • Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome

    Troy J. Pereira;Mario A. Fonseca;Kristyn E. Campbell;Brittany L. Moyce

  • FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

    Grant M. Hatch;Anne J. Smith;Fred Y. Xu;Angela M. Hall

Frequent Co-Authors

Dennis E. Vance
Dennis E. Vance University of Alberta
Saeid Ghavami
Saeid Ghavami University of Manitoba
Elissavet Kardami
Elissavet Kardami University of Manitoba
Thomas Klonisch
Thomas Klonisch University of Manitoba
Joaquín Madrenas
Joaquín Madrenas University of California, Los Angeles
Richard M. Epand
Richard M. Epand McMaster University
Spencer B. Gibson
Spencer B. Gibson University of Manitoba
Andrew J. Halayko
Andrew J. Halayko University of Manitoba
Mona Nemer
Mona Nemer University of Ottawa
Kenneth R. Feingold
Kenneth R. Feingold University of California, San Francisco

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