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Biology and Biochemistry

D-Index
46
Citations
10093
World Ranking
18871
National Ranking
603

Overview

Giuseppe Petrosillo is affiliated with the National Research Council (CNR) in Italy, focusing on areas within biochemistry, genetics, and molecular biology. Their work largely concentrates on mitochondrial function and pathology, exploring the molecular mechanisms that underpin mitochondrial health and disease.

Their research spans topics including:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Metabolism and Genetic Disorders
  • RNA modifications and cancer
  • Biochemical Acid Research Studies
  • Coenzyme Q10 studies and effects
  • Diet and metabolism studies

Recent publications illustrate the breadth of their research interests. Key papers include:

  • "Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs," published in 2022 in Molecules
  • "Targeting mitochondrial impairment for the treatment of cardiovascular diseases: From hypertension to ischemia-reperfusion injury, searching for new pharmacological targets," published in 2023 in Biochemical Pharmacology
  • "Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT7 Receptor," published in 2020 in International Journal of Molecular Sciences
  • "Retrograde response to mitochondrial dysfunctions associated to LOF variations in FLAD1 exon 2: unraveling the importance of RFVT2," published in 2022 in Free Radical Research
  • "Exploring the Ability of LARS2 Carboxy-Terminal Domain in Rescuing the MELAS Phenotype," published in 2021 in Life

Their research has been disseminated frequently in journals such as:

  • International Journal of Molecular Sciences
  • Molecules
  • Biochemical Pharmacology
  • Free Radical Research
  • Life

Collaborative efforts appear frequently in their work. Frequent co-authors include:

  • Domenico Marzulli
  • Ciro Leonardo Pierri
  • Maria Tolomeo
  • Alessia De Nisco
  • Tiziana Latronico

The subfields of study associated with their publications include molecular biology, clinical biochemistry, materials chemistry, cancer research, and biochemistry.

Best Publications

  • Decrease in Mitochondrial Complex I Activity in Ischemic/Reperfused Rat Heart. Involvement of Reactive Oxygen Species and Cardiolipin

    Giuseppe Paradies;Giuseppe Petrosillo;Marilva Pistolese;Nicola Di Venosa

  • Functional role of cardiolipin in mitochondrial bioenergetics.

    Giuseppe Paradies;Valeria Paradies;Valentina De Benedictis;Francesca M. Ruggiero

  • Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease.

    Giuseppe Paradies;Valeria Paradies;Francesca M Ruggiero;Giuseppe Petrosillo

  • Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage.

    Giuseppe Paradies;Giuseppe Petrosillo;Marilva Pistolese;Francesca Maria Ruggiero

  • Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease.

    Giuseppe Paradies;Giuseppe Paradies;Giuseppe Petrosillo;Giuseppe Petrosillo;Valeria Paradies;Valeria Paradies;Russel J. Reiter;Russel J. Reiter

  • Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria

    Giuseppe Petrosillo;Francesca M. Ruggiero;Giuseppe Paradies

  • Role of Cardiolipin in Mitochondrial Function and Dynamics in Health and Disease: Molecular and Pharmacological Aspects.

    Giuseppe Paradies;Valeria Paradies;Francesca M. Ruggiero;Giuseppe Petrosillo

  • The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine heart submitochondrial particles

    Giuseppe Paradies;Giuseppe Petrosillo;Marilva Pistolese;Francesca Maria Ruggiero

  • Lipid peroxidation and alterations to oxidative metabolism in mitochondria isolated from rat heart subjected to ischemia and reperfusion.

    Giuseppe Paradies;Giuseppe Petrosillo;Marilva Pistolese;Nicola Di Venosa

  • Decreased complex III activity in mitochondria isolated from rat heart subjected to ischemia and reperfusion: role of reactive oxygen species and cardiolipin

    Giuseppe Petrosillo;Francesca M Ruggiero;Nicola Di Venosa;Giuseppe Paradies

  • Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beef-heart submitochondrial particles via cardiolipin peroxidation. Possible role in the apoptosis.

    Giuseppe Petrosillo;Francesca Maria Ruggiero;Marilva Pistolese;Giuseppe Paradies

  • Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease

    Giuseppe Paradies;Giuseppe Petrosillo;Valeria Paradies;Francesca M. Ruggiero

  • Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin.

    Giuseppe Paradies;Giuseppe Petrosillo;Valeria Paradies;Francesca M. Ruggiero

  • Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin.

    Giuseppe Petrosillo;Piero Portincasa;Ignazio Grattagliano;Giacoma Casanova

  • Ca2+-induced reactive oxygen species production promotes cytochrome c release from rat liver mitochondria via mitochondrial permeability transition (MPT)-dependent and MPT-independent mechanisms: role of cardiolipin.

    Giuseppe Petrosillo;Francesca M. Ruggiero;Marilva Pistolese;Giuseppe Paradies

  • Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging.

    Giuseppe Paradies;Giuseppe Petrosillo;Valeria Paradies;Francesca M. Ruggiero

  • Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.

    Giuseppe Petrosillo;Giuseppe Colantuono;Nicola Moro;Francesca Maria Ruggiero

  • Age‐dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin

    Giuseppe Paradies;Francesca Maria Ruggiero;Giuseppe Petrosillo;Ernesto Quagliariello

  • Protective effect of melatonin against mitochondrial dysfunction associated with cardiac ischemia-reperfusion : role of cardiolipin

    G. Petrosillo;N. Di Venosa;M. Pistolese;G. Casanova

  • Mitochondrial dysfunction in rat brain with aging Involvement of complex I, reactive oxygen species and cardiolipin.

    Petrosillo G;Matera M;Casanova G;Ruggiero Fm

Frequent Co-Authors

Giuseppe Paradies
Giuseppe Paradies University of Bari Aldo Moro
Francesca Maria Ruggiero
Francesca Maria Ruggiero University of Bari Aldo Moro
Piero Portincasa
Piero Portincasa University of Bari Aldo Moro
Russel J. Reiter
Russel J. Reiter The University of Texas Health Science Center at San Antonio
Valerio Carelli
Valerio Carelli University of Bologna
Maria Lucia Valentino
Maria Lucia Valentino University of Bologna
Carla Giordano
Carla Giordano Sapienza University of Rome
Mauro Fasano
Mauro Fasano University of Insubria
Maria Chiara Monti
Maria Chiara Monti University of Salerno
Alfredo A. Sadun
Alfredo A. Sadun University of California, Los Angeles

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