World's Best Scientists 2026 revealed!
Maria Lucia Valentino

Maria Lucia Valentino

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9469
World Ranking
15728
National Ranking
492

Overview

Maria Lucia Valentino is affiliated with the University of Bologna in Italy. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, contributing extensively to subfields such as molecular biology, neurology, rheumatology, clinical biochemistry, and cellular and molecular neuroscience.

Their scientific work focuses on several main topics including mitochondrial function and pathology, metabolism and genetic disorders, genetic neurodegenerative diseases, ATP synthase and ATPases research, RNA modifications and cancer, glycogen storage diseases and myoclonus, and neurological diseases and metabolism.

Maria Lucia Valentino has published numerous research articles in prominent scientific journals. Frequent publication venues include:

  • Journal of Neurology
  • Scientific Reports
  • Neurology Genetics
  • Annals of Clinical and Translational Neurology
  • Radiotherapy and Oncology

Recent papers by Valentino cover varied aspects of mitochondrial and neurological research. These include:

  • Expanding and validating the biomarkers for mitochondrial diseases, 2020, Journal of Molecular Medicine
  • Mitochondrial diseases in adults, 2020, Journal of Internal Medicine
  • Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome, 2020, Scientific Reports
  • ATPase Domain AFG3L2 Mutations Alter OPA1 Processing and Cause Optic Neuropathy, 2020, Annals of Neurology
  • Anti-cN1A Antibodies Are Associated with More Severe Dysphagia in Sporadic Inclusion Body Myositis, 2021, Cells

Throughout their research career, Valentino has collaborated frequently with several coauthors, including:

  • Valério Carelli
  • Chiara La Morgia
  • Leonardo Caporali
  • Rocco Liguori
  • Alessandra Maresca

Their academic output is characterized by a consistent contribution to understanding mitochondrial diseases and related biochemical and neurological disorders. Valentino's work intersects clinical studies with molecular and cellular approaches, reflecting an integrative perspective on disease mechanisms and pathology.

Best Publications

  • OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes

    Patrizia Amati-Bonneau;Maria Lucia Valentino;Pascal Reynier;Maria Esther Gallardo

  • Multi-system neurological disease is common in patients with OPA1 mutations

    Patrick Yu-Wai-Man;Philip G. Griffiths;Philip G. Griffiths;G. Gorman;C.-M. Lourenco

  • OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion.

    Claudia Zanna;Anna Ghelli;Anna Maria Porcelli;Mariusz Karbowski

  • Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background

    Gavin Hudson;Valerio Carelli;Valerio Carelli;Liesbeth Spruijt;Mike Gerards

  • Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy.

    Carla Giordano;Luisa Iommarini;Luca Giordano;Alessandra Maresca

  • Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders

    Valerio Carelli;Chiara La Morgia;Maria Lucia Valentino;Piero Barboni

  • Haplogroup effects and recombination of mitochondrial DNA: novel clues from the analysis of Leber hereditary optic neuropathy pedigrees.

    Valerio Carelli;Valerio Carelli;Alessandro Achilli;Maria Lucia Valentino;Chiara Rengo

  • ALLOGENEIC STEM CELL TRANSPLANTATION CORRECTS BIOCHEMICAL DERANGEMENTS IN MNGIE

    M. Hirano;R. Martí;C. Casali;S. Tadesse

  • Phenotypic heterogeneity of the 8344A>G mtDNA "MERRF" mutation

    Michelangelo Mancuso;Daniele Orsucci;Corrado Angelini;Enrico Bertini

  • Syndromic parkinsonism and dementia associated with OPA1 missense mutations

    Valerio Carelli;Olimpia Musumeci;Leonardo Caporali;Claudia Zanna

  • Extensive investigation of a large Brazilian pedigree of 11778/haplogroup J Leber hereditary optic neuropathy.

    Alfredo A. Sadun;Valerio Carelli;Valerio Carelli;Solange R. Salomao;Solange R. Salomao;Adriana Berezovsky

  • Visual system involvement in patients with Friedreich's ataxia

    Filippo Fortuna;Piero Barboni;Rocco Liguori;Maria Lucia Valentino

  • Deficit of in vivo mitochondrial ATP production in OPA1-related dominant optic atrophy

    R. Lodi;C. Tonon;M.L. Valentino;S. Iotti

  • Retinal nerve fiber layer evaluation by optical coherence tomography in unaffected carriers with Leber's hereditary optic neuropathy mutations

    Giacomo Savini;Piero Barboni;Maria Lucia Valentino;Pasquale Montagna

  • The m.3243A>G mitochondrial DNA mutation and related phenotypes. A matter of gender?

    Michelangelo Mancuso;Daniele Orsucci;Corrado Angelini;Enrico Bertini

  • Infusion of platelets transiently reduces nucleoside overload in MNGIE.

    M. C. Lara;B. Weiss;I. Illa;P. Madoz

  • The ND1 gene of complex I is a mutational hot spot for Leber’s hereditary optic neuropathy☆

    M.L. Valentino;P. Barboni;A. Ghelli;L. Bucchi

  • Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways.

    L Giordano;S Deceglie;P d'Adamo;M L Valentino

  • Evidence for a novel x-linked modifier locus for leber hereditary optic neuropathy.

    Suma P. Shankar;John H. Fingert;Valerio Carelli;Maria L. Valentino

  • Gastrointestinal Dysmotility in Mitochondrial Neurogastrointestinal Encephalomyopathy Is Caused by Mitochondrial DNA Depletion

    Carla Giordano;Mariangela Sebastiani;Roberto De Giorgio;Claudia Travaglini

Frequent Co-Authors

Valerio Carelli
Valerio Carelli University of Bologna
Rocco Liguori
Rocco Liguori University of Bologna
Pasquale Montagna
Pasquale Montagna University of Bologna
Massimo Zeviani
Massimo Zeviani University of Padua
Alfredo A. Sadun
Alfredo A. Sadun University of California, Los Angeles
Bernd Wissinger
Bernd Wissinger University of Tübingen
Antonio Torroni
Antonio Torroni University of Pavia
Alessandro Achilli
Alessandro Achilli University of Pavia
Michio Hirano
Michio Hirano Columbia University
Pietro Cortelli
Pietro Cortelli University of Bologna

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry studies in the USA opens doors to a wide range of related fields and career opportunities. For students looking to connect science with real-world health and wellness, programs like fitness degrees online offer a practical route, blending biology fundamentals with exercise science principles.

Another popular path is pursuing a kinesiology online degree, which focuses on human movement, physiology, and rehabilitation. This can be ideal for those who wish to work in sports, healthcare, or physical therapy environments.

If you’re interested in direct patient care and advanced healthcare roles, there are specialized programs such as the shortest online pmhnp certificate programs for psychiatric mental health nurse practitioners, as well as accelerated options like the 12-month fnp program online for aspiring nurse practitioners.

These online degrees and certificates enable students to advance their careers in flexible, accessible formats, all while building on the foundational knowledge gained in Biology and Biochemistry.

Best Scientists Citing Maria Lucia Valentino

Trending Scientists

Recently Published Articles