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Biology and Biochemistry

D-Index
49
Citations
10765
World Ranking
17932
National Ranking
625

Overview

Margaret E. Brosnan is a researcher affiliated with Memorial University of Newfoundland in Canada. Their work primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with additional focus on subfields including rheumatology, clinical biochemistry, molecular biology, physiology, and organic chemistry.

Their research concentrates on several main topics:

  • Folate and B Vitamins Research
  • Metabolism and Genetic Disorders
  • Biochemical effects in animals
  • Free Radicals and Antioxidants
  • Aldose Reductase and Taurine
  • Birth, Development, and Health
  • Cancer-related Molecular Pathways

Among recent publications authored or co-authored by Margaret E. Brosnan are:

  • Histidine Metabolism and Function, 2020, Journal of Nutrition
  • Reduced Shmt2 Expression Impairs Mitochondrial Folate Accumulation and Respiration, and Leads to Uracil Accumulation in Mouse Mitochondrial DNA, 2021, Journal of Nutrition
  • Oncogenic Ras expression increases cellular formate production, 2021, Amino Acids
  • Reduced Shmt2 expression impairs mitochondrial folate accumulation and respiration, and leads to uracil accumulation in mouse mitochondrial DNA, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Abstract 2578 Identifying Endogenous mRNA Targets of Inosine Monophosphate Dehydrogenase, 2025, Journal of Biological Chemistry

The frequent co-authors collaborating with Brosnan include:

  • John T. Brosnan
  • Joanna Fiddler
  • Yuwen Xiu
  • Jamie Blum
  • Simon G. Lamarre

Publication venues where their work is often featured include:

  • Journal of Nutrition
  • Amino Acids
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry

Best Publications

  • The Sulfur-Containing Amino Acids: An Overview

    John T. Brosnan;Margaret E. Brosnan

  • Branched-Chain Amino Acids: Enzyme and Substrate Regulation

    James T. Brosnan;Margaret E. Brosnan

  • Creatine: endogenous metabolite, dietary, and therapeutic supplement.

    John T. Brosnan;Margaret E. Brosnan

  • Is it time to reevaluate methyl balance in humans

    Lori M Stead;John T Brosnan;Margaret E Brosnan;Dennis E Vance

  • Glutamate: a truly functional amino acid

    John T. Brosnan;Margaret E. Brosnan

  • The metabolic burden of creatine synthesis

    John T. Brosnan;Robin P. da Silva;Margaret E. Brosnan

  • Renal arginine synthesis: studies in vitro and in vivo.

    S N Dhanakoti;J T Brosnan;G R Herzberg;M E Brosnan

  • Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat.

    R L Jacobs;J D House;M E Brosnan;J T Brosnan

  • Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate

    Lori M. Stead;Keegan P. Au;René L. Jacobs;Margaret E. Brosnan

  • Hepatic glutamate metabolism: a tale of 2 hepatocytes

    Margaret E Brosnan;John T Brosnan

  • Amino acid metabolism in the Zucker diabetic fatty rat: effects of insulin resistance and of type 2 diabetes.

    Enoka P Wijekoon;Craig Skinner;Margaret E Brosnan;John T Brosnan

  • Methylation demand: a key determinant of homocysteine metabolism

    John T Brosnan;Rene L Jacobs;Lori M Stead;Margaret E Brosnan

  • Methyl balance and transmethylation fluxes in humans

    S Harvey Mudd;John T Brosnan;Margaret E Brosnan;René L Jacobs

  • Hormonal Regulation of Cystathionine β-Synthase Expression in Liver

    Shobhitha Ratnam;Kenneth N. Maclean;Rene L. Jacobs;Margaret E. Brosnan

  • Characterization of homocysteine metabolism in the rat liver.

    Lori M. Stead;Margaret E. Brosnan;John T. Brosnan

  • Renal Arginine Metabolism

    Margaret E. Brosnan;John T. Brosnan

  • Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

    Yun Jin Pai;Kit-Yi Leung;Dawn Savery;Tim Hutchin

  • Creatine Synthesis: Hepatic Metabolism of Guanidinoacetate and Creatine in the Rat, in vitro and in vivo

    Robin P. da Silva;Itzhak Nissim;Margaret E. Brosnan;John T. Brosnan

  • Histidine Metabolism and Function.

    Margaret E Brosnan;John T Brosnan

  • Plasma homocysteine is regulated by phospholipid methylation.

    Anna A. Noga;Lori M. Stead;Yang Zhao;Margaret E. Brosnan

Frequent Co-Authors

John T. Brosnan
John T. Brosnan Memorial University of Newfoundland
Itzhak Nissim
Itzhak Nissim Children's Hospital of Philadelphia
Dennis E. Vance
Dennis E. Vance University of Alberta
Anne M. Molloy
Anne M. Molloy Trinity College Dublin
Sally P. Stabler
Sally P. Stabler University of Colorado Anschutz Medical Campus
Per Magne Ueland
Per Magne Ueland University of Bergen
Andrew J. Copp
Andrew J. Copp University College London
Barry Shane
Barry Shane University of California, Berkeley
Nicholas D. E. Greene
Nicholas D. E. Greene University College London
Marc Yudkoff
Marc Yudkoff Children's Hospital of Philadelphia

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