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Biology and Biochemistry

D-Index
59
Citations
10755
World Ranking
12713
National Ranking
5420

Overview

Barry Shane is affiliated with the University of California, Berkeley in the United States. Their research spans multiple fields primarily focused on Medicine and Biochemistry, Genetics and Molecular Biology.

Their scholarly output includes investigations in the subfields of Rheumatology, Molecular Biology, Clinical Biochemistry, Physiology, and Surgery. The main topics addressed in their work are Folate and B Vitamins Research, Metabolism and Genetic Disorders, Mitochondrial Function and Pathology, Nutrition and Health in Aging, Esophageal and Gastrointestinal Pathology, Biochemical and Molecular Research, and Acute Lymphoblastic Leukemia research.

Barry Shane has contributed to several notable publications, including:

  • Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop (2020), published in American Journal of Clinical Nutrition
  • Folinate Supplementation Ameliorates Methotrexate Induced Mitochondrial Formate Depletion In Vitro and In Vivo (2021), published in International Journal of Molecular Sciences
  • SLC25A48 influences plasma levels of choline and localizes to the inner mitochondrial membrane (2024), published in Molecular Genetics and Metabolism
  • Slc25a48 is a Good Candidate for the Inner Mitochondrial Membrane Choline Transporter (2024), published in SSRN Electronic Journal

The frequent co-authors collaborating with Barry Shane include Anne M. Molloy, David J. Bernard, Faith Pangilinan, Tara Desporte, and Stephen Wincovitch.

The primary publication venues for Shane's research are:

  • American Journal of Clinical Nutrition
  • International Journal of Molecular Sciences
  • Molecular Genetics and Metabolism
  • SSRN Electronic Journal

Their research mainly addresses topics relevant to nutrient metabolism, mitochondrial function, and molecular mechanisms underlying metabolic disorders and clinical nutrition. Recent work explores folate metabolism and mitochondrial transport processes.

Best Publications

  • Biomarkers of Nutrition for Development (BOND)-Iron Review.

    Sean Lynch;Christine M Pfeiffer;Michael K Georgieff;Gary Brittenham

  • Folylpolyglutamate Synthesis and Role in the Regulation of One-Carbon Metabolism

    Barry Shane

  • Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

    Dawn L. Harmon;Denis C. Shields;Jayne V. Woodside;Dorothy McMaster

  • Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia.

    Christine F. Skibola;Martyn T. Smith;Alan Hubbard;Barry Shane

  • Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.

    A. Katherine Herbig;En-Pei Chiang;Ling-Ru Lee;Jessica Hills

  • Folic Acid and L-5-Methyltetrahydrofolate: Comparison of Clinical Pharmacokinetics and Pharmacodynamics

    Klaus Pietrzik;Lynn Bailey;Barry Shane

  • FOLATE CHEMISTRY AND METABOLISM

    Barry Shane

  • Human Methionine Synthase: cDNA CLONING, GENE LOCALIZATION, AND EXPRESSION *

    Linda H. Chen;Mei-Lan Liu;Hye-Yeon Hwang;Li-Sheng Chen

  • Biomarkers of vitamin B-12 status in NHANES: a roundtable summary

    Elizabeth A Yetley;Christine M Pfeiffer;Karen W Phinney;Regan L Bailey

  • Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.

    T. A. Garrow;A. A. Brenner;V. M. Whitehead;Xiao-Ning Chen

  • Targeted Disruption of the Methionine Synthase Gene in Mice

    Deborah A. Swanson;Mei-Lan Liu;Priscilla J. Baker;Lisa Garrett

  • Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor

    Steven R. Davis;Peter W. Stacpoole;Jerry Williamson;Lilia S. Kick

  • A Mathematical Model Gives Insights into Nutritional and Genetic Aspects of Folate-Mediated One-Carbon Metabolism

    Michael C. Reed;H. Frederik Nijhout;Marian L. Neuhouser;Jesse F. Gregory

  • Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene

    Patrick J. Stover;Linda H. Chen;Jae Rin Suh;Denise M. Stover

  • Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase. Cloning and high expression of the Escherichia coli folC gene and purification and properties of the gene product.

    A L Bognar;C Osborne;B Shane;S C Singer

  • Hyperhomocysteinemia Due to Methionine Synthase Deficiency, cblG: Structure of the MTR Gene, Genotype Diversity, and Recognition of a Common Mutation, P1173L

    David Watkins;Ming Ru;Hye-Yeon Hwang;Caroline D. Kim

  • Folate and vitamin B12 metabolism: overview and interaction with riboflavin, vitamin B6, and polymorphisms.

    Barry Shane

  • Serine Hydroxymethyltransferase Anchors de Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis

    Donald D. Anderson;Collynn F. Woeller;En-Pei Chiang;En-Pei Chiang;Barry Shane

  • Biomarkers of folate status in NHANES: a roundtable summary

    Elizabeth A Yetley;Christine M Pfeiffer;Karen W Phinney;Zia Fazili

  • Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficiency or excess. Part I--Folate, Vitamin B12, Vitamin B6.

    Joe Leigh Simpson;Lynn B Bailey;Klaus Pietrzik;Barry Shane

Frequent Co-Authors

Anne M. Molloy
Anne M. Molloy Trinity College Dublin
James L. Mills
James L. Mills National Institutes of Health
Lawrence C. Brody
Lawrence C. Brody National Institutes of Health
Jesse F. Gregory
Jesse F. Gregory University of Florida
Patrick J. Stover
Patrick J. Stover Texas A&M University
Per Magne Ueland
Per Magne Ueland University of Bergen
Jacob Selhub
Jacob Selhub Tufts University
John M. Scott
John M. Scott Trinity College Dublin
Cornelia M. Ulrich
Cornelia M. Ulrich University of Utah
Joan E. Bailey-Wilson
Joan E. Bailey-Wilson National Institutes of Health

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