D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 119 Citations 55,332 308 World Ranking 1607 National Ranking 965

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Enzyme
  • Gene

His scientific interests lie mostly in Internal medicine, Homocysteine, Endocrinology, Risk factor and Hyperhomocysteinemia. His study in Vitamin B12, Odds ratio, Prospective cohort study, Case-control study and Vascular disease are all subfields of Internal medicine. His research in Homocysteine intersects with topics in Framingham Heart Study, Framingham Risk Score, Cardiology, Stroke and Transsulfuration.

His Endocrinology research is multidisciplinary, relying on both Methylenetetrahydrofolate reductase and Methionine. His work deals with themes such as Gastroenterology and Gerontology, which intersect with Risk factor. He combines subjects such as Homocystinuria, Surgery, Renal function, Kidney and End stage renal disease with his study of Hyperhomocysteinemia.

His most cited work include:

  • Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease (2651 citations)
  • Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population (1746 citations)
  • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis (1663 citations)

What are the main themes of his work throughout his whole career to date?

Jacob Selhub mainly focuses on Internal medicine, Endocrinology, Homocysteine, Hyperhomocysteinemia and Gastroenterology. His research links Methylenetetrahydrofolate reductase with Internal medicine. His Endocrinology research includes elements of Biochemistry and Genotype.

His research in Homocysteine tackles topics such as Odds ratio which are related to areas like Stroke and Confidence interval. Jacob Selhub has included themes like Transplantation, Kidney disease, End stage renal disease, Hemodialysis and Kidney in his Hyperhomocysteinemia study. His study looks at the relationship between Gastroenterology and fields such as Colorectal cancer, as well as how they intersect with chemical problems.

He most often published in these fields:

  • Internal medicine (71.28%)
  • Endocrinology (51.70%)
  • Homocysteine (48.56%)

What were the highlights of his more recent work (between 2012-2021)?

  • Internal medicine (71.28%)
  • Endocrinology (51.70%)
  • Homocysteine (48.56%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Endocrinology, Homocysteine, Gastroenterology and Folic acid. His Internal medicine study combines topics from a wide range of disciplines, such as Methylenetetrahydrofolate reductase, Pyridoxal and Oncology. His Endocrinology research incorporates elements of Offspring, Biochemistry and Immunology.

The concepts of his Homocysteine study are interwoven with issues in Framingham Heart Study, Genetics and B vitamins. The study incorporates disciplines such as Vitamin B12 and Cohort in addition to Gastroenterology. His studies deal with areas such as Surgery, Young adult, Cell survival, Mitochondrial DNA and Cytotoxicity as well as Folic acid.

Between 2012 and 2021, his most popular works were:

  • Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease (113 citations)
  • Excessive folic acid intake and relation to adverse health outcome (75 citations)
  • Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation. (72 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Gene

Jacob Selhub mostly deals with Internal medicine, Endocrinology, Homocysteine, Pregnancy and Physiology. He combines subjects such as Gastroenterology and Methylenetetrahydrofolate reductase with his study of Internal medicine. His Endocrinology research integrates issues from Pyridoxal, Colorectal cancer and Immunology.

Specifically, his work in Homocysteine is concerned with the study of Hyperhomocysteinemia. His Pregnancy study integrates concerns from other disciplines, such as Folic acid, Case-control study, Environmental exposure and Surgery. His Physiology study combines topics from a wide range of disciplines, such as Offspring, Vitamin B12, Insulin resistance, Arsenic toxicity and Exposed Population.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

Sudha Seshadri;Alexa Beiser;Jacob Selhub;Paul F Jacques.
The New England Journal of Medicine (2002)

3779 Citations

Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population

Jacob Selhub;Paul F. Jacques;Peter W. F. Wilson;David Rush.
JAMA (1993)

2696 Citations

Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis

R. Clarke;R. Collins;S. Lewington;A. Donald.
JAMA (2002)

2361 Citations

Relation Between Folate Status, a Common Mutation in Methylenetetrahydrofolate Reductase, and Plasma Homocysteine Concentrations

Paul F. Jacques;Andrew G. Bostom;Roger R. Williams;R. Curtis Ellison.
Circulation (1996)

1759 Citations

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

Jacob Selhub;Paul F. Jacques;Andrew G. Bostom;Ralph B. D'Agostino.
The New England Journal of Medicine (1995)

1650 Citations

Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death

Thomas J. Wang;Thomas J. Wang;Philimon Gona;Philimon Gona;Martin G. Larson;Martin G. Larson;Geoffrey H. Tofler.
The New England Journal of Medicine (2006)

1527 Citations

The Effect of Folic Acid Fortification on Plasma Folate and Total Homocysteine Concentrations

Paul F. Jacques;Jacob Selhub;Andrew G. Bostom;Peter W.F. Wilson.
The New England Journal of Medicine (1999)

1418 Citations

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status

Simonetta Friso;Sang-Woon Choi;Domenico Girelli;Joel B. Mason.
Proceedings of the National Academy of Sciences of the United States of America (2002)

1064 Citations

Methylenetetrahydrofolate Reductase Polymorphism, Dietary Interactions, and Risk of Colorectal Cancer

Jing Ma;Meir J. Stampfer;Edward Giovannucci;Carmen Artigas.
Cancer Research (1997)

951 Citations

Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort

Paul F Jacques;Andrew G Bostom;Peter Wf Wilson;Sharron Rich.
The American Journal of Clinical Nutrition (2001)

824 Citations

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