D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 51 Citations 11,921 106 World Ranking 12475 National Ranking 896

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Hartmut Kleinert mainly investigates Molecular biology, Nitric oxide synthase, Gene isoform, Messenger RNA and Transcription factor. His Molecular biology research includes themes of Cell culture, Gene expression, Pyrrolidine dithiocarbamate, Regulation of gene expression and Kinase. His Regulation of gene expression research is multidisciplinary, incorporating elements of Signal transduction, STAT protein and stat.

His study on Nitric oxide synthase is covered under Internal medicine. His Gene isoform research is multidisciplinary, relying on both Isozyme, Enzyme, Nitric oxide and Transcriptional regulation. Much of his study explores Transcription factor relationship to Cell biology.

His most cited work include:

  • Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. (960 citations)
  • Regulation of the expression of inducible nitric oxide synthase. (615 citations)
  • Expressional control of the 'constitutive' isoforms of nitric oxide synthase (NOS I and NOS III). (589 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Molecular biology, Nitric oxide synthase, Cell biology, Biochemistry and Messenger RNA. His work deals with themes such as Cell culture, Transfection, Promoter, Gene expression and Regulation of gene expression, which intersect with Molecular biology. The study incorporates disciplines such as Transcription factor and Gene isoform in addition to Nitric oxide synthase.

His Transcription factor research incorporates elements of Pyrrolidine dithiocarbamate and STAT protein. His Gene isoform research is multidisciplinary, incorporating perspectives in Isozyme, ATP synthase, Enzyme and Aorta. Hartmut Kleinert has researched Cell biology in several fields, including T cell and Downregulation and upregulation.

He most often published in these fields:

  • Molecular biology (36.36%)
  • Nitric oxide synthase (31.31%)
  • Cell biology (24.24%)

What were the highlights of his more recent work (between 2012-2020)?

  • Cell biology (24.24%)
  • Messenger RNA (21.21%)
  • Molecular biology (36.36%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Messenger RNA, Molecular biology, Inflammation and Immunology. His research in Cell biology intersects with topics in T cell, Regulation of gene expression, Translational regulation and Leaky scanning. The various areas that Hartmut Kleinert examines in his Messenger RNA study include Interferon, Gene expression and Immunoprecipitation.

His work on Flow cytometry as part of general Molecular biology research is frequently linked to Peripheral blood mononuclear cell, thereby connecting diverse disciplines of science. His Inflammation study combines topics from a wide range of disciplines, such as Endocrinology, Endothelial dysfunction and Protein kinase B. He has included themes like Platelet activation, Apocynin and Endothelin 1 in his Nitric oxide synthase study.

Between 2012 and 2020, his most popular works were:

  • Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol. (90 citations)
  • Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression (63 citations)
  • Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity (35 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Internal medicine, Endocrinology, Resveratrol, Molecular biology and Enos are his primary areas of study. His is involved in several facets of Internal medicine study, as is seen by his studies on Endothelial dysfunction, Nitric oxide synthase, Oxidative stress and Inflammation. His work carried out in the field of Endocrinology brings together such families of science as Histone, Histone methyltransferase, Histone methyltransferase activity, Histone H3 Lysine 4 and DNA methylation.

Hartmut Kleinert interconnects Electrophoretic mobility shift assay, Transcription factor, FOXO1, Gene knockdown and Reporter gene in the investigation of issues within Resveratrol. As a member of one scientific family, Hartmut Kleinert mostly works in the field of Molecular biology, focusing on RNA-binding protein and, on occasion, p38 mitogen-activated protein kinases and Cell biology. His studies in Enos integrate themes in fields like NADPH oxidase, Apocynin and Endothelin 1.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.

U Förstermann;E I Closs;J S Pollock;M Nakane.
Hypertension (1994)

1592 Citations

Regulation of the expression of inducible nitric oxide synthase.

Hartmut Kleinert;Andrea Pautz;Katrin Linker;Petra M. Schwarz.
European Journal of Pharmacology (2004)

932 Citations

Expressional control of the 'constitutive' isoforms of nitric oxide synthase (NOS I and NOS III).

Ulrich Förstermann;Jean‐Paul Boissel;Hartmut Kleinert.
The FASEB Journal (1998)

885 Citations

Nitric oxide synthase: expression and expressional control of the three isoforms

Ulrich Förstermann;Hartmut Kleinert.
Naunyn-schmiedebergs Archives of Pharmacology (1995)

643 Citations

Regulation of the Expression of Inducible Nitric Oxide Synthase

Hartmut Kleinert;Petra M Schwarz;Ulrich Förstermann.
Biological Chemistry (2003)

536 Citations

Regulation of the expression of inducible nitric oxide synthase

Andrea Pautz;Julia Art;Susanne Hahn;Sebastian Nowag.
Nitric Oxide (2010)

520 Citations

Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control.

Ulrich Förstermann;Ingolf Gath;Petra Schwarz;Ellen I. Closs.
Biochemical Pharmacology (1995)

495 Citations

Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension.

Thomas Wallerath;Klaus Witte;Stephan C. Schäfer;Petra M. Schwarz.
Proceedings of the National Academy of Sciences of the United States of America (1999)

374 Citations

Estrogens increase transcription of the human endothelial NO synthase gene: analysis of the transcription factors involved.

Hartmut Kleinert;Thomas Wallerath;Christian Euchenhofer;Irmgard Ihrig-Biedert.
Hypertension (1998)

335 Citations

Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B.

H Kleinert;C Euchenhofer;I Ihrig-Biedert;U Förstermann.
Molecular Pharmacology (1996)

333 Citations

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