Hartmut Kleinert mainly investigates Molecular biology, Nitric oxide synthase, Gene isoform, Messenger RNA and Transcription factor. His Molecular biology research includes themes of Cell culture, Gene expression, Pyrrolidine dithiocarbamate, Regulation of gene expression and Kinase. His Regulation of gene expression research is multidisciplinary, incorporating elements of Signal transduction, STAT protein and stat.
His study on Nitric oxide synthase is covered under Internal medicine. His Gene isoform research is multidisciplinary, relying on both Isozyme, Enzyme, Nitric oxide and Transcriptional regulation. Much of his study explores Transcription factor relationship to Cell biology.
The scientist’s investigation covers issues in Molecular biology, Nitric oxide synthase, Cell biology, Biochemistry and Messenger RNA. His work deals with themes such as Cell culture, Transfection, Promoter, Gene expression and Regulation of gene expression, which intersect with Molecular biology. The study incorporates disciplines such as Transcription factor and Gene isoform in addition to Nitric oxide synthase.
His Transcription factor research incorporates elements of Pyrrolidine dithiocarbamate and STAT protein. His Gene isoform research is multidisciplinary, incorporating perspectives in Isozyme, ATP synthase, Enzyme and Aorta. Hartmut Kleinert has researched Cell biology in several fields, including T cell and Downregulation and upregulation.
His main research concerns Cell biology, Messenger RNA, Molecular biology, Inflammation and Immunology. His research in Cell biology intersects with topics in T cell, Regulation of gene expression, Translational regulation and Leaky scanning. The various areas that Hartmut Kleinert examines in his Messenger RNA study include Interferon, Gene expression and Immunoprecipitation.
His work on Flow cytometry as part of general Molecular biology research is frequently linked to Peripheral blood mononuclear cell, thereby connecting diverse disciplines of science. His Inflammation study combines topics from a wide range of disciplines, such as Endocrinology, Endothelial dysfunction and Protein kinase B. He has included themes like Platelet activation, Apocynin and Endothelin 1 in his Nitric oxide synthase study.
Internal medicine, Endocrinology, Resveratrol, Molecular biology and Enos are his primary areas of study. His is involved in several facets of Internal medicine study, as is seen by his studies on Endothelial dysfunction, Nitric oxide synthase, Oxidative stress and Inflammation. His work carried out in the field of Endocrinology brings together such families of science as Histone, Histone methyltransferase, Histone methyltransferase activity, Histone H3 Lysine 4 and DNA methylation.
Hartmut Kleinert interconnects Electrophoretic mobility shift assay, Transcription factor, FOXO1, Gene knockdown and Reporter gene in the investigation of issues within Resveratrol. As a member of one scientific family, Hartmut Kleinert mostly works in the field of Molecular biology, focusing on RNA-binding protein and, on occasion, p38 mitogen-activated protein kinases and Cell biology. His studies in Enos integrate themes in fields like NADPH oxidase, Apocynin and Endothelin 1.
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Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.
U Förstermann;E I Closs;J S Pollock;M Nakane.
Hypertension (1994)
Regulation of the expression of inducible nitric oxide synthase.
Hartmut Kleinert;Andrea Pautz;Katrin Linker;Petra M. Schwarz.
European Journal of Pharmacology (2004)
Expressional control of the 'constitutive' isoforms of nitric oxide synthase (NOS I and NOS III).
Ulrich Förstermann;Jean‐Paul Boissel;Hartmut Kleinert.
The FASEB Journal (1998)
Nitric oxide synthase: expression and expressional control of the three isoforms
Ulrich Förstermann;Hartmut Kleinert.
Naunyn-schmiedebergs Archives of Pharmacology (1995)
Regulation of the Expression of Inducible Nitric Oxide Synthase
Hartmut Kleinert;Petra M Schwarz;Ulrich Förstermann.
Biological Chemistry (2003)
Regulation of the expression of inducible nitric oxide synthase
Andrea Pautz;Julia Art;Susanne Hahn;Sebastian Nowag.
Nitric Oxide (2010)
Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control.
Ulrich Förstermann;Ingolf Gath;Petra Schwarz;Ellen I. Closs.
Biochemical Pharmacology (1995)
Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension.
Thomas Wallerath;Klaus Witte;Stephan C. Schäfer;Petra M. Schwarz.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Estrogens increase transcription of the human endothelial NO synthase gene: analysis of the transcription factors involved.
Hartmut Kleinert;Thomas Wallerath;Christian Euchenhofer;Irmgard Ihrig-Biedert.
Hypertension (1998)
Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B.
H Kleinert;C Euchenhofer;I Ihrig-Biedert;U Förstermann.
Molecular Pharmacology (1996)
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