Gerhard Fritz

Research.com Recognitions

• 1970 - Alfred-Stock-Gedächtnispreis (Alfred Stock Memorial Prize), German Chemical Society

Overview

Best Publications

• CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

  Imke Tiede;Gerhard Fritz;Susanne Strand;Daniela Poppe

  1024
  Citations

• Rho GTPases are over‐expressed in human tumors

  Gerhard Fritz;Ingo Just;Bernd Kaina

  980
  Citations

• Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters.

  G Fritz;C Brachetti;F Bahlmann;M Schmidt

  503
  Citations

• Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue

  Ursula Münstermann;Gerhard Fritz;Gerhard Seitz;Lu Yiping

  294
  Citations

• Clostridium difficile toxin B acts on the GTP-binding protein Rho.

  I Just;G Fritz;K Aktories;M Giry

  279
  Citations

• Rho GTPases: promising cellular targets for novel anticancer drugs.

  Gerhard Fritz;Bernd Kaina

  266
  Citations

• Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins

  Daniela Poppe;Imke Tiede;Gerhard Fritz;Christoph Becker

  253
  Citations

• The Ras-related Small GTP-binding Protein RhoB Is Immediate-early Inducible by DNA Damaging Treatments

  Gerhard Fritz;Bernd Kaina;Klaus Aktories

  228
  Citations

• Cytokine induction of NO synthase II in human DLD‐1 cells: roles of the JAK‐STAT, AP‐1 and NF‐κB‐signaling pathways

  Hartmut Kleinert;Thomas Wallerath;Gerhard Fritz;Irmgard Ihrig-Biedert

  202
  Citations

• Long‐term activation of SAPK/JNK, p38 kinase and fas‐L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance

  Anamaria Brozovic;Gerhard Fritz;Markus Christmann;Jochen Zisowsky

  195
  Citations

• Lovastatin inhibits Rho-regulated expression of E-selectin by TNF-α and attenuates tumor cell adhesion

  Tobias Nübel;Wolfgang Dippold;Hartmut Kleinert;Bernd Kaina

  157
  Citations

• Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo.

  Christian Ostrau;Johannes Hülsenbeck;Melanie Herzog;Arno Schad

  153
  Citations

• APE/Ref-1 and the mammalian response to genotoxic stress.

  Gerhard Fritz;Sabine Grösch;Maja Tomicic;Bernd Kaina

  133
  Citations

• Premature Senescence Is a Primary Fail-safe Mechanism of ERBB2-Driven Tumorigenesis in Breast Carcinoma Cells

  Tatjana M. Trost;Ekkehart U. Lausch;Stephan A. Fees;Steffen Schmitt

  129
  Citations

• BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis

  Kaina B;Ochs K;Grösch S;Fritz G

  129
  Citations

• Lovastatin Protects Human Endothelial Cells from Killing by Ionizing Radiation without Impairing Induction and Repair of DNA Double-Strand Breaks

  Tobias Nübel;Julia Damrot;Wynand P. Roos;Bernd Kaina

  127
  Citations

• rhoB Encoding a UV-inducible Ras-related Small GTP-binding Protein Is Regulated by GTPases of the Rho Family and Independent of JNK, ERK, and p38 MAP Kinase

  Gerhard Fritz;Bernd Kaina

  123
  Citations

• Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac.

  Maria Lerm;Marius Pop;Gerhard Fritz;Klaus Aktories

  123
  Citations

• Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity

  J Huelsenbeck;C Henninger;A Schad;K J Lackner

  109
  Citations

• Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide

  J Damrot;T Nübel;B Epe;W P Roos

  103
  Citations