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Emmanuel Lemichez

Emmanuel Lemichez

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
9265
World Ranking
18650
National Ranking
857

Overview

Emmanuel Lemichez is affiliated with the Institut Pasteur in France. Their research spans several fields and focuses heavily on molecular biology and neurological disorders with a particular emphasis on botulinum toxins and their mechanisms.

Their main fields of study include Biochemistry, Genetics and Molecular Biology, and Medicine. More specifically, their work delves into subfields such as Molecular Biology, Neurology, Infectious Diseases, Cell Biology, and Immunology.

The topics covered in their research are diverse and include:

  • Botulinum Toxin and Related Neurological Disorders
  • Neurological disorders and treatments
  • Lipid Membrane Structure and Behavior
  • Clostridium difficile and Clostridium perfringens research
  • Gut microbiota and health
  • Hereditary Neurological Disorders
  • Toxin Mechanisms and Immunotoxins

Emmanuel Lemichez has contributed to a number of scientific publications published across several venues. Their most frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Toxins
  • Gut Microbes
  • Toxicon
  • eLife

Some of their recent papers are:

  • Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes, 2023, published in Gut Microbes
  • Human Botulism in France, 1875-2016, 2020, published in Toxins
  • The colibactin-producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance, 2024, published in Gut Microbes
  • Neuronal selectivity of botulinum neurotoxins, 2020, published in Toxicon
  • Toxemia in Human Naturally Acquired Botulism, 2020, published in Toxins

Throughout their career, Emmanuel Lemichez has collaborated frequently with several scientists, including:

  • Amel Mettouchi
  • Michel R. Popoff
  • Christine Rasetti-Escargueil
  • Maud Marechal
  • Landry Laure Tsoumtsa

Best Publications

  • Rac Homologues and Compartmentalized Phosphatidylinositol 4, 5-Bisphosphate Act in a Common Pathway to Regulate Polar Pollen Tube Growth

    Benedikt Kost;Emmanuel Lemichez;Pius Spielhofer;Yan Hong

  • Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

    Gilles Flatau;Emmanuel Lemichez;Michel Gauthier;Pierre Chardin

  • Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

    A Nusrat;M Giry;J R Turner;S P Colgan

  • Integrin-specific activation of Rac controls progression through the G1 phase of the cell cycle

    Amel Mettouchi;Sharon Klein;Wenjun Guo;Wenjun Guo;Miguel Lopez-Lago

  • CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion.

    Anne Doye;Amel Mettouchi;Guillaume Bossis;René Clément

  • Inactivation of AtRac1 by abscisic acid is essential for stomatal closure

    Emmanuel Lemichez;Yan Wu;Juan-Pablo Sanchez;Amel Mettouchi

  • Ras, Rap, and Rac Small GTP-binding Proteins Are Targets for Clostridium sordellii Lethal Toxin Glucosylation

    Michel R. Popoff;Esteban Chaves-Olarte;Emmanuel Lemichez;Emmanuel Lemichez;Christoph von Eichel-Streiber

  • Oxytocin controls differentiation of human mesenchymal stem cells and reverses osteoporosis.

    Christian Elabd;Armelle Basillais;Hélène Beaupied;Véronique Breuil

  • IRSp53 senses negative membrane curvature and phase separates along membrane tubules

    Coline Prévost;Hongxia Zhao;John Manzi;John Manzi;John Manzi;Emmanuel Lemichez

  • Functional Analysis of Four Tetraspans, CD9, CD53, CD81, and CD82, Suggests a Common Role in Costimulation, Cell Adhesion, and Migration: Only CD9 Upregulates HB-EGF Activity

    Cécile Lagaudrière-Gesbert;François Le Naour;Sophie Lebel-Binay;Martine Billard

  • Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells

    Malvyne Rolli-Derkinderen;Vincent Sauzeau;Laurent Boyer;Emmanuel Lemichez

  • Inhibition of RhoA Translocation and Calcium Sensitization by In Vivo ADP-Ribosylation with the Chimeric Toxin DC3B

    Hideyoshi Fujihara;Lori A. Walker;Ming Cui Gong;Emmanuel Lemichez

  • Bacterial virulence factors targeting Rho GTPases: parasitism or symbiosis?

    Patrice Boquet;Emmanuel Lemichez

  • The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1.

    Stéphanie Torrino;Orane Visvikis;Orane Visvikis;Anne Doye;Anne Doye;Laurent Boyer;Laurent Boyer

  • Breaking the wall: targeting of the endothelium by pathogenic bacteria

    Emmanuel Lemichez;Emmanuel Lemichez;Marc Lecuit;Marc Lecuit;Marc Lecuit;Xavier Nassif;Xavier Nassif;Sandrine Bourdoulous;Sandrine Bourdoulous

  • System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes

    Wei Zhang;Kuen Phon Wu;Maria A. Sartori;Hari B. Kamadurai

  • Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell‐binding and catalytic domains

    Emmanuel Lemichez;Gilles Flatau;Marc Bruzzone;Patrice Boquet

  • MEMBRANE TRANSLOCATION OF DIPHTHERIA TOXIN FRAGMENT A EXPLOITS EARLY TO LATE ENDOSOME TRAFFICKING MACHINERY

    E Lemichez;M Bomsel;G Devilliers;J vanderSpek

  • Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions

    Arnaud Jacquel;Sandrine Obba;Laurent Boyer;Laurent Boyer;Maeva Dufies

  • ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion.

    Sandra Sousa;Didier Cabanes;Cristel Archambaud;Frédéric Colland

Frequent Co-Authors

Patrice Boquet
Patrice Boquet Grenoble Alpes University
Patricia Bassereau
Patricia Bassereau Institute Curie
Michel R. Popoff
Michel R. Popoff Institut Pasteur
Pekka Lappalainen
Pekka Lappalainen University of Helsinki
Patrick Auberger
Patrick Auberger Grenoble Alpes University
Jean-François Peyron
Jean-François Peyron Grenoble Alpes University
Xavier Nassif
Xavier Nassif Université Paris Cité
Jean-Philippe Lavigne
Jean-Philippe Lavigne University of Montpellier
Marc Lecuit
Marc Lecuit Institut Pasteur
Guerrino Meneguzzi
Guerrino Meneguzzi Université Côte d'Azur

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