Jean-Louis Mege spends much of his time researching Microbiology, Immunology, Coxiella burnetii, Q fever and Monocyte. He has researched Microbiology in several fields, including Tropheryma whipplei, Macrophage and Gene expression profiling. His works in Immune system, Cytokine, Tumor necrosis factor alpha, Interleukin and Proinflammatory cytokine are all subjects of inquiry into Immunology.
His studies deal with areas such as Innate immune system and Intracellular parasite as well as Coxiella burnetii. His Q fever study integrates concerns from other disciplines, such as Meningitis, Rickettsiosis, Mannose receptor and Hepatitis. His Macrophage polarization research incorporates themes from Macrophage colony-stimulating factor, Computational biology and Macrophage.
Jean-Louis Mege mostly deals with Immunology, Coxiella burnetii, Microbiology, Immune system and Q fever. The study incorporates disciplines such as Peripheral blood mononuclear cell and Endocarditis in addition to Immunology. His Coxiella burnetii research focuses on subjects like Tumor necrosis factor alpha, which are linked to Secretion.
While the research belongs to areas of Microbiology, Jean-Louis Mege spends his time largely on the problem of Macrophage, intersecting his research to questions surrounding Bacteria. The concepts of his Immune system study are interwoven with issues in Inflammation and Placenta. The Q fever study combines topics in areas such as Antibody and Pathogenesis.
His primary scientific interests are in Immunology, Immune system, Coxiella burnetii, Internal medicine and Placenta. His Immunology research includes elements of Downregulation and upregulation and Pathophysiology. Jean-Louis Mege combines subjects such as Tumor necrosis factor alpha, Pathogenesis, Crosstalk, Cell type and Circadian rhythm with his study of Immune system.
His Coxiella burnetii study is associated with Microbiology. Within one scientific family, Jean-Louis Mege focuses on topics pertaining to Extracellular under Microbiology, and may sometimes address concerns connected to Virulence and Antimicrobial peptides. As part of one scientific family, Jean-Louis Mege deals mainly with the area of Q fever, narrowing it down to issues related to the Cytokine, and often Effector and CD14.
Jean-Louis Mege mainly investigates Immunology, Immune system, Coxiella burnetii, Q fever and Myeloid. He interconnects In vitro and Disease in the investigation of issues within Immunology. His research integrates issues of Personalized treatment, Fetus, Macrophage and Chronobiology in his study of Immune system.
His work deals with themes such as Whole blood, Fold change, Pathogen and Transcriptome, which intersect with Coxiella burnetii. His Q fever research incorporates elements of Pathology, Lymphoma, Coxiella burnetii Infection, Interstitial lung disease and Lung biopsy. His Myeloid study also includes
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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher.
Immunity (2014)
Macrophage Polarization in Bacterial Infections
Marie Benoit;Benoît Desnues;Jean-Louis Mege.
Journal of Immunology (2008)
Natural history and pathophysiology of Q fever
D Raoult;TJ Marrie;JL Mege.
Lancet Infectious Diseases (2005)
Patterns of cytokine evolution (tumor necrosis factor-alpha and interleukin-6) after septic shock, hemorrhagic shock, and severe trauma.
Claude Martin;Christophe Boisson;Martine Haccoun;Laurent Thomachot.
Critical Care Medicine (1997)
Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behçet's disease. A comparative study with familial Mediterranean fever and healthy subjects.
J L Mege;N Dilsen;V Sanguedolce;A Gul.
The Journal of Rheumatology (1993)
From Q Fever to Coxiella burnetii Infection: a Paradigm Change.
Carole Eldin;Cléa Mélenotte;Oleg Mediannikov;Eric Ghigo.
Clinical Microbiology Reviews (2017)
The two faces of interleukin 10 in human infectious diseases
Jean-Louis Mege;Soraya Meghari;Amélie Honstettre;Christian Capo.
Lancet Infectious Diseases (2006)
Virulent Brucella abortus Prevents Lysosome Fusion and Is Distributed within Autophagosome-Like Compartments
Javier Pizarro-Cerdá;Edgardo Moreno;Veronique Sanguedolce;Jean-Louis Mege.
Infection and Immunity (1998)
Ameobal Pathogen Mimivirus Infects Macrophages through Phagocytosis
Eric Ghigo;Jürgen Kartenbeck;Pham Thi Kim Lien;Lucas Pelkmans.
PLOS Pathogens (2008)
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-γ mediates its restoration and bacterial killing
Eric Ghigo;Christian Capo;Ching-Hsuan Tung;Didier Raoult.
Journal of Immunology (2002)
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