D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 67 Citations 12,611 146 World Ranking 5369 National Ranking 156

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Bacteria

Cell biology, Molecular biology, Biochemistry, GTPase and RHOA are his primary areas of study. Patrice Boquet has researched Cell biology in several fields, including MDia1, Cell culture and Endocytic cycle, Endocytosis. His Molecular biology research incorporates themes from GTP-binding protein regulators, Protein kinase A, Cytosol, Clostridium difficile toxin A and Clostridium perfringens.

The study incorporates disciplines such as Pathogen, Pathogenic bacteria, Crosstalk and Virulence in addition to GTPase. He works mostly in the field of RHOA, limiting it down to topics relating to CDC42 and, in certain cases, Cell morphology, Phosphorylation and Clostridium sordellii. As a part of the same scientific study, Patrice Boquet usually deals with the Microbiology, concentrating on Transferase and frequently concerns with Toxin.

His most cited work include:

  • Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine (436 citations)
  • The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells. (435 citations)
  • Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. (376 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Biochemistry, Molecular biology, Toxin and Microbiology. His research on Cell biology also deals with topics like

  • Actin cytoskeleton which intersects with area such as Phagocytosis,
  • Cytoskeleton which is related to area like Actin. His Molecular biology research includes elements of Vero cell, Clostridium botulinum, ADP-ribosylation and G protein.

His research in Toxin tackles topics such as Liposome which are related to areas like Phosphatidylcholine and Membrane. His Microbiology research is multidisciplinary, incorporating perspectives in Virulence factor, Helicobacter pylori, Apoptosis, Bacteria and Escherichia coli. His GTPase study combines topics in areas such as Clostridium difficile toxin A, Clostridium difficile toxin B, Deamidation and RHOA.

He most often published in these fields:

  • Cell biology (34.48%)
  • Biochemistry (28.97%)
  • Molecular biology (28.28%)

What were the highlights of his more recent work (between 2001-2015)?

  • Cell biology (34.48%)
  • Microbiology (24.83%)
  • Endosome (7.59%)

In recent papers he was focusing on the following fields of study:

Patrice Boquet spends much of his time researching Cell biology, Microbiology, Endosome, GTPase and Helicobacter pylori. The study incorporates disciplines such as Clostridium difficile toxin A, Internalization, Biochemistry and Cytosol in addition to Cell biology. His research integrates issues of Diphtheria toxin, Actin cytoskeleton and Cell membrane in his study of Cytosol.

His Microbiology study combines topics from a wide range of disciplines, such as Cancer, Secretion, Escherichia coli, Bacteria and Gastric mucosa. His work deals with themes such as Protein structure and Signal transduction, which intersect with GTPase. His Helicobacter pylori study integrates concerns from other disciplines, such as CagA, Virulence, Apoptosis, Toxin and Immunology.

Between 2001 and 2015, his most popular works were:

  • CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. (220 citations)
  • Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. (174 citations)
  • Bacterial virulence factors targeting Rho GTPases: parasitism or symbiosis? (136 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Bacteria

Patrice Boquet mostly deals with Cell biology, Endosome, Helicobacter pylori, Virulence and Microbiology. His study in Cell biology focuses on RHOA and GTPase. His GTPase research is multidisciplinary, relying on both Clostridium difficile toxin A, Virulence factor and Cytosol.

Patrice Boquet works mostly in the field of Endosome, limiting it down to concerns involving Clathrin and, occasionally, Cytoskeleton, Lipid raft, Cdc42 GTP-Binding Protein, Endocytic cycle and Dynamin. His studies deal with areas such as CagA, Mechanism of action, Toxin and Apoptosis, Inner mitochondrial membrane as well as Helicobacter pylori. His work carried out in the field of Microbiology brings together such families of science as Mitochondrion and Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

P. Chardin;P. Boquet;P. Madaule;M. R. Popoff.
The EMBO Journal (1989)

710 Citations

Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

Gilles Flatau;Emmanuel Lemichez;Michel Gauthier;Pierre Chardin.
Nature (1997)

554 Citations

Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

A Nusrat;M Giry;J R Turner;S P Colgan.
Proceedings of the National Academy of Sciences of the United States of America (1995)

498 Citations

The N‐terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release

Antoine Galmiche;Joachim Rassow;Anne Doye;Sebastien Cagnol.
The EMBO Journal (2000)

446 Citations

Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain.

M R Popoff;E J Rubin;D M Gill;P Boquet.
Infection and Immunity (1988)

437 Citations

Large clostridial cytotoxins — a family of glycosyltransferases modifying small GTP-binding proteins

Christoph von Eichel-Streiber;Patrice Boquet;Markus Sauerborn;Monica Thelestam.
Trends in Microbiology (1996)

334 Citations

CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion.

Anne Doye;Amel Mettouchi;Guillaume Bossis;René Clément.
Cell (2002)

319 Citations

Regulation of the Actin Cytoskeleton by Thrombin in Human Endothelial Cells: Role of Rho Proteins in Endothelial Barrier Function

Valérie Vouret-Craviari;Patrice Boquet;Jacques Pouysségur;Ellen Van Obberghen-Schilling.
Molecular Biology of the Cell (1998)

275 Citations

Ras, Rap, and Rac Small GTP-binding Proteins Are Targets for Clostridium sordellii Lethal Toxin Glucosylation

Michel R. Popoff;Esteban Chaves-Olarte;Emmanuel Lemichez;Emmanuel Lemichez;Christoph von Eichel-Streiber.
Journal of Biological Chemistry (1996)

251 Citations

Characterization of Clostridium perfringens Iota-toxin genes and expression in Escherichia coli.

S Perelle;M Gibert;P Boquet;M R Popoff.
Infection and Immunity (1993)

243 Citations

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