Her scientific interests lie mostly in Biochemistry, Molecular biology, Stereochemistry, DNA and Cyclin-dependent kinase. As part of her studies on Biochemistry, Doris Marko often connects relevant subjects like Biophysics. Doris Marko combines subjects such as Apoptosis and Growth inhibition with her study of Molecular biology.
The concepts of her DNA study are interwoven with issues in Cell culture and Genotoxicity. Her work in Genotoxicity tackles topics such as Topoisomerase-II Inhibitor which are related to areas like Alternariol. Her Cyclin-dependent kinase research incorporates themes from Cyclin-dependent kinase 1, Kinase and Cyclin-dependent kinase 2.
Her primary areas of study are Biochemistry, Mycotoxin, Alternariol, Topoisomerase and Food science. Her study in DNA damage, Cell growth, In vitro, Reactive oxygen species and Phosphorylation are all subfields of Biochemistry. Her study looks at the relationship between DNA damage and topics such as Molecular biology, which overlap with Cell cycle and Cell culture.
Her Phosphorylation research incorporates elements of Kinase and Epidermal growth factor receptor. Her Alternariol research is multidisciplinary, incorporating elements of Aryl hydrocarbon receptor, Cytochrome P450, Genotoxicity and Formamidopyrimidine DNA glycosylase. Doris Marko works mostly in the field of Topoisomerase, limiting it down to topics relating to Pharmacology and, in certain cases, Delphinidin, as a part of the same area of interest.
Doris Marko mainly focuses on Mycotoxin, Alternariol, Food science, Alternaria and In vitro. Her Mycotoxin research includes themes of Food safety, Breast milk, Food contaminant and Environmental health. Her Alternariol research is multidisciplinary, relying on both Receptor, Secretion, Biochemistry, Estrogen receptor and Cell biology.
Her research in Biochemistry is mostly focused on Drug metabolism. Her work focuses on many connections between Food science and other disciplines, such as Genotoxicity, that overlap with her field of interest in Comet assay. Her In vitro research includes elements of Metabolite and In silico.
Doris Marko mostly deals with Mycotoxin, Alternaria, Alternariol, Food science and Tenuazonic acid. Her Mycotoxin study incorporates themes from Food safety and Cell biology. Her studies in Alternaria integrate themes in fields like Toxin, Mode of action and Biochemistry.
The study incorporates disciplines such as DNA damage, Comet assay, Aryl hydrocarbon receptor, Estrogen receptor and Alkaline phosphatase in addition to Toxin. Her study connects Tumor necrosis factor alpha and Alternariol. Her work deals with themes such as Blood lipids, Cell damage, Polyphenol and Type 2 diabetes, which intersect with Food science.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases.
Ralph Hoessel;Sophie Leclerc;Jane A. Endicott;Martin E. M. Nobel.
Nature Cell Biology (1999)
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease A PROPERTY COMMON TO MOST CYCLIN-DEPENDENT KINASE INHIBITORS?
Sophie Leclerc;Matthieu Garnier;Ralph Hoessel;Doris Marko.
Journal of Biological Chemistry (2001)
The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor.
S. Meiers;M. Kemény;U. Weyand;R. Gastpar.
Journal of Agricultural and Food Chemistry (2001)
Proposal of a comprehensive definition of modified and other forms of mycotoxins including “masked” mycotoxins
Michael Rychlik;Hans-Ulrich Humpf;Doris Marko;Sven Dänicke.
Mycotoxin Research (2014)
Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells
D Marko;S Schätzle;A Friedel;A Genzlinger.
British Journal of Cancer (2001)
Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression.
Ute Boettler;Katharina Sommerfeld;Nadine Volz;Nadine Volz;Gudrun Pahlke.
Journal of Nutritional Biochemistry (2011)
Inhibitor Binding to Active and Inactive CDK2: The Crystal Structure of CDK2-Cyclin A/Indirubin-5-Sulphonate
Thomas G. Davies;Paul Tunnah;Laurent Meijer;Doris Marko.
Structure (2001)
Alternariol acts as a topoisomerase poison, preferentially affecting the IIα isoform
Markus Fehr;Gudrun Pahlke;Jessica Fritz;Morten O. Christensen.
Molecular Nutrition & Food Research (2009)
Nitrate and nitrite in the diet: How to assess their benefit and risk for human health
Michael Habermeyer;Angelika Roth;Sabine Guth;Patrick Diel.
Molecular Nutrition & Food Research (2015)
Cellular uptake of platinum nanoparticles in human colon carcinoma cells and their impact on cellular redox systems and DNA integrity.
Joanna Pelka;Helge Gehrke;Melanie Esselen;Michael Türk.
Chemical Research in Toxicology (2009)
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