World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
8048
World Ranking
18069
National Ranking
219

Overview

Yong Chul Kim is affiliated with the Gwangju Institute of Science and Technology in South Korea. Their research activity is situated primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, contributing extensively to both areas through numerous publications.

The main subfields of Kim's work include Molecular Biology, Organic Chemistry, Physiology, Hematology, and Genetics. These domains align closely with the focused topics covered in their research outputs, which encompass Adenosine and Purinergic Signaling, Acute Myeloid Leukemia Research, Pharmacological Receptor Mechanisms and Effects, Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, Chronic Myeloid Leukemia Treatments, and Quinazolinone synthesis and applications.

Kim's publication record shows frequent contributions to several key scientific journals. Notably, they have published multiple papers in the Journal of Medicinal Chemistry and the European Journal of Medicinal Chemistry. Other venues include Pharmaceuticals, UNC Libraries, and Bioorganic & Medicinal Chemistry Letters, reflecting a broad engagement with medicinal chemistry and pharmaceutical sciences.

Their recent published research includes the following papers:

  • Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m6A Methylation of RNA in Acute Myeloid Leukemia Cells, 2022, Pharmaceuticals
  • Interplay among Conformation, Intramolecular Hydrogen Bonds, and Chameleonicity in the Membrane Permeability and Cyclophilin A Binding of Macrocyclic Peptide Cyclosporin O Derivatives, 2021, Journal of Medicinal Chemistry
  • Discovery of orally active indirubin-3'-oxime derivatives as potent type 1 FLT3 inhibitors for acute myeloid leukemia, 2020, European Journal of Medicinal Chemistry
  • AI-based prediction of new binding site and virtual screening for the discovery of novel P2X3 receptor antagonists, 2022, European Journal of Medicinal Chemistry
  • Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents, 2021, Journal of Medicinal Chemistry

Collaboration is a discernible aspect of Kim's research environment, frequently co-authoring papers with several experts including Pyeonghwa Jeong, Koon Mook Kang, Je-Heon Lee, Mi Sun Jin, and Sun-Young Han.

Best Publications

  • Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors.

    Yong-Chul Kim;Xiao-duo Ji;Neli Melman;Joel Linden

  • Derivatives of the Triazoloquinazoline Adenosine Antagonist (CGS15943) Are Selective for the Human A3 Receptor Subtype

    Yong-Chul Kim;Xiao-duo Ji;Kenneth A. Jacobson

  • Structure–activity relationships of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists

    Kwan-Young Jung;Soo-Kyung Kim;Zhan-Guo Gao;Ariel S Gross

  • MIPs are ancestral ligands for the sex peptide receptor

    Young-Joon Kim;Katarina Bartalska;Neil Audsley;Naoki Yamanaka

  • Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.

    Kenneth A. Jacobson;Kyung-Sun Park;Ji-Long Jiang;Yong-Chul Kim

  • A mutational analysis of residues essential for ligand recognition at the human P2Y1 receptor

    Qiaoling Jiang;Danping Guo;Brian X. Lee;A. Michiel Van Rhee

  • Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities

    Myoung Ju Moon;Sang Kook Lee;Jong-Won Lee;Woo Keun Song

  • Activation of ATM depends on chromatin interactions occurring before induction of DNA damage

    Yong-Chul Kim;Gabi Gerlitz;Takashi Furusawa;Frédéric Catez

  • A novel flavin-containing monooxygenase from Methylophaga sp strain SK1 and its indigo synthesis in Escherichia coli.

    Hack Sun Choi;Jin Kwon Kim;Eun Hee Cho;Yong Chul Kim

  • FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease.

    Tae In Kam;Sungmin Song;Youngdae Gwon;Hyejin Park

  • Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells.

    Yunjo Soh;Kyu-Shik Jeong;Insong James Lee;Myung-Ae Bae

  • ADENOSINE A3 RECEPTOR AGONISTS PROTECT HL-60 AND U-937 CELLS FROM APOPTOSIS INDUCED BY A3 ANTAGONISTS

    Yao Yao;Yoshitatsu Sei;Maria P. Abbracchio;Ji-Long Jiang

  • Subdermal Flexible Solar Cell Arrays for Powering Medical Electronic Implants.

    Kwangsun Song;Jung Hyun Han;Taehoon Lim;Namyun Kim

  • Selective cytotoxicity following Arg-to-Lys substitution in tritrpticin adopting a unique amphipathic turn structure.

    Sung Tae Yang;Song Yub Shin;Chul Won Lee;Yong Chul Kim

  • Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes.

    Y C Kim;M de Zwart;L Chang;S Moro

  • Myeloid-Derived Suppressor Cells Are Controlled by Regulatory T Cells via TGF-β during Murine Colitis

    Cho-Rong Lee;Yewon Kwak;Taewoo Yang;Jung Hyun Han

  • Structure-Activity Relationships of Pyridoxal Phosphate Derivatives as Potent and Selective Antagonists of P2X1 Receptors

    Kim Yc;Brown Sg;Harden Tk;Boyer Jl

  • Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo

    Huiling Hu;Wennan Lu;Mei Zhang;Xiulan Zhang

  • [3H]MRS 1754, a selective antagonist radioligand for A2B adenosine receptors

    Xiao-duoseqkat Ji;Yong-Chul Kim;David G Ahern;Joel Linden

  • Pharmacological characterization of novel A 3 adenosine receptor-selective antagonists

    Kenneth A. Jacobson;Kyung-Sun Park;Ji-Long Jiang;Yong-Chul Kim

Frequent Co-Authors

Kenneth A. Jacobson
Kenneth A. Jacobson National Institutes of Health
Sang Kook Lee
Sang Kook Lee Seoul National University
Stefano Moro
Stefano Moro University of Padua
José L. Boyer
José L. Boyer Inspire Pharmaceuticals
Lak Shin Jeong
Lak Shin Jeong Seoul National University
Geoffrey Burnstock
Geoffrey Burnstock University College London
T. Kendall Harden
T. Kendall Harden University of North Carolina at Chapel Hill
Joel Linden
Joel Linden University of Virginia
Sangyong Jon
Sangyong Jon Korea Advanced Institute of Science and Technology
Tae Sung Kim
Tae Sung Kim Korea University

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