José L. Boyer

Overview

Best Publications

• International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy

  Maria Pia Abbracchio;Geoffrey Burnstock;Jean-Marie Boeynaems;Eric A Barnard

  1568
  Citations

• Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family.

  Maria Pia Abbracchio;Jean-Marie Boeynaems;Eric A Barnard;José L Boyer

  559
  Citations

• P2-Purinergic Receptors: Subtype-Associated Signaling Responses and Structure

  T K Harden;J L Boyer;R A Nicholas

  496
  Citations

• Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor

  Joel B. Schachter;Qing Li;José L. Boyer;Robert A. Nicholas

  354
  Citations

• Identification of competitive antagonists of the P2Y1 receptor.

  J L Boyer;T Romero-Avila;J B Schachter;T K Harden

  352
  Citations

• Beta gamma-subunit activation of G-protein-regulated phospholipase C.

  J.L. Boyer;G.L. Waldo;T.K. Harden

  278
  Citations

• Kinetics of activation of phospholipase C by P2Y purinergic receptor agonists and guanine nucleotides.

  J L Boyer;C P Downes;T K Harden

  273
  Citations

• Expression of a cloned P2Y purinergic receptor that couples to phospholipase C.

  T M Filtz;Q Li;J L Boyer;R A Nicholas

  254
  Citations

• Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate

  José L Boyer;Arvind Mohanram;Emidio Camaioni;Kenneth A Jacobson

  247
  Citations

• Agonist Action of Adenosine Triphosphates at the Human P2Y1 Receptor

  R. Kyle Palmer;José L. Boyer;Joel B. Schachter;Robert A. Nicholas

  234
  Citations

• Pharmacology of INS37217 [P(1)-(uridine 5')-P(4)- (2'-deoxycytidine 5')tetraphosphate, tetrasodium salt], a next-generation P2Y(2) receptor agonist for the treatment of cystic fibrosis.

  B. R. Yerxa;J. R. Sabater;C. W. Davis;M. J. Stutts

  216
  Citations

• Differential effects of P2‐purinoceptor antagonists on phospholipase C‐ and adenylyl cyclase‐coupled P2Y‐purinoceptors

  José L. Boyer;Irene E. Zohn;Kenneth A. Jacobson;T. Kendall Harden

  210
  Citations

• Human P2Y1 Receptor: Molecular Modeling and Site-Directed Mutagenesis as Tools To Identify Agonist and Antagonist Recognition Sites

  Stefano Moro;Danping Guo;Emidio Camaioni;José L. Boyer

  207
  Citations

• ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor

  Nancy McNamara;Amy Khong;David McKemy;Mike Caterina

  199
  Citations

• Purification of an AlF4- and G-protein beta gamma-subunit-regulated phospholipase C-activating protein.

  G.L. Waldo;J.L. Boyer;A.J. Morris;T.K. Harden

  178
  Citations

• Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase.

  J. L. Boyer;E. R. Lazarowski;Xiao-Hua Chen;T. K. Harden

  168
  Citations

• Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors.

  Camaioni E;Boyer Jl;Mohanram A;Harden Tk

  167
  Citations

• Selective activation of phospholipase C by recombinant G-protein alpha- and beta gamma-subunits.

  J L Boyer;S G Graber;G L Waldo;T K Harden

  162
  Citations

• Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands.

  E Nandanan;S Y Jang;S Moro;H O Kim

  159
  Citations

• Identification of Potent, Selective P2Y-Purinoceptor Agonists: Structure–Activity Relationships for 2-Thioether Derivatives of Adenosine 5′-Triphosphate

  B. Fischer;J. L. Boyer;C. H. V. Hoyle;A. U. Ziganshin

  150
  Citations