His main research concerns Extracellular, Cell biology, Biochemistry, Molecular biology and Nucleoside triphosphate. His Extracellular study integrates concerns from other disciplines, such as Cell growth, Ectonucleotidase, Transfection, Transmembrane domain and Bile duct. His studies deal with areas such as Neuroscience, Enteric nervous system, Neuroglia and Glial fibrillary acidic protein as well as Cell biology.
His research related to Receptor, Enzyme, Apyrase, ATP hydrolysis and Adenosine monophosphate might be considered part of Biochemistry. His Molecular biology research includes themes of ATPase, Purinergic receptor, Adult stem cell, Complementary DNA and Neural stem cell. His Nucleoside triphosphate research incorporates elements of Transduction, Protein subunit, Taste, G protein and TAS1R3.
His primary scientific interests are in Biochemistry, Extracellular, Enzyme, Cell biology and Receptor. His Molecular biology research extends to Biochemistry, which is thematically connected. His Extracellular research focuses on subjects like Adenosine, which are linked to Purinergic signalling, Adenosine receptor and ATP hydrolysis.
His Enzyme research includes elements of In vitro, Structure–activity relationship and Recombinant DNA. His research on Cell biology often connects related areas such as Cell. His Apyrase study incorporates themes from Ectonucleotidase, ATPase, Pharmacology and Adenosine triphosphate.
His scientific interests lie mostly in Biochemistry, Enzyme, Cancer research, Nucleotide and Adenosine. The various areas that he examines in his Enzyme study include Ectonucleotidase, In vitro and Stereochemistry. His Ectonucleotidase study combines topics from a wide range of disciplines, such as Capillary electrophoresis and Apyrase.
His research in Nucleotide intersects with topics in Extracellular and Docking. His research integrates issues of ATP hydrolysis, Imatinib, Inflammatory bowel disease and Adenine nucleotide in his study of Extracellular. His primary area of study in Adenosine is in the field of Purinergic receptor.
His main research concerns Cancer research, Glioma, Stereochemistry, Phosphodiesterase and In vitro. His In vitro research integrates issues from Cell, Antibody, Nucleotide and Islet. His research investigates the connection between Cell and topics such as Cell biology that intersect with issues in Stromal cell.
In Isozyme, Jean Sévigny works on issues like Thiazole, which are connected to Biochemistry. As a member of one scientific family, Jean Sévigny mostly works in the field of Adenosine, focusing on Immunohistochemistry and, on occasion, Extracellular. His Enzyme research is multidisciplinary, relying on both Druglikeness, Ectonucleotidase and Mechanism of action.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance
Simon Christopher Robson;Jean Sévigny;Herbert Zimmermann.
Purinergic Signalling (2006)
Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase
Elzbieta Kaczmarek;Katarzyna Koziak;Jean Sévigny;Jonathan B. Siegel.
Journal of Biological Chemistry (1996)
Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation
Keiichi Enjyoji;Jean Sévigny;Yuan Lin;Paul S. Frenette.
Nature Medicine (1999)
Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants
K. Sato;J. Balla;L. Otterbein;R. N. Smith.
Journal of Immunology (2001)
CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
Norikatsu Mizumoto;Tadashi Kumamoto;Simon C. Robson;Jean Sévigny.
Nature Medicine (2002)
Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8.
F. Kukulski;S. A. Lévesque;É. G. Lavoie;J. Lecka.
Purinergic Signalling (2005)
Transforming growth factor-β and substrate stiffness regulate portal fibroblast activation in culture
Zhaodong Li;Jonathan A. Dranoff;Erick P. Chan;Masayuki Uemura.
Hepatology (2007)
Targeted Disruption of cd73/Ecto-5′-Nucleotidase Alters Thromboregulation and Augments Vascular Inflammatory Response
Patrycja Koszalka;Burcin Özüyaman;Yuqing Huo;Alma Zernecke.
Circulation Research (2004)
Nucleoside Triphosphate diphosphohydrolase-2 Is the ecto-ATPase of Type I Cells in Taste Buds
Dianna L. Bartel;Susan L. Sullivan;Élise G. Lavoie;Jean Sévigny.
The Journal of Comparative Neurology (2006)
CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
David J. Friedman;Beat M. Künzli;Yousif I. A-Rahim;Jean Sevigny.
Proceedings of the National Academy of Sciences of the United States of America (2009)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
Beth Israel Deaconess Medical Center
Goethe University Frankfurt
University of Bonn
Université Libre de Bruxelles
University of Pennsylvania
Harvard Medical School
University of Angers
University of Karachi
University of New South Wales
University of Auckland
Grenoble Alpes University
Case Western Reserve University
University of Parma
Queensland University of Technology
Universitat Politècnica de València
University of Virginia
Pennsylvania State University
University of Arizona
United States Air Force Research Laboratory
Government of India
New York State Department of Health
Centre national de la recherche scientifique, CNRS
University of California, Irvine
Duke University
McMaster University
University of California, Los Angeles