Jean Sévigny

Overview

Best Publications

• The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

  Simon Christopher Robson;Jean Sévigny;Herbert Zimmermann

  1073
  Citations

• Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase

  Elzbieta Kaczmarek;Katarzyna Koziak;Jean Sévigny;Jonathan B. Siegel

  701
  Citations

• Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

  Keiichi Enjyoji;Jean Sévigny;Yuan Lin;Paul S. Frenette

  635
  Citations

• Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants

  K. Sato;J. Balla;L. Otterbein;R. N. Smith

  604
  Citations

• CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness

  Norikatsu Mizumoto;Tadashi Kumamoto;Simon C. Robson;Jean Sévigny

  409
  Citations

• Transforming growth factor-β and substrate stiffness regulate portal fibroblast activation in culture

  Zhaodong Li;Jonathan A. Dranoff;Erick P. Chan;Masayuki Uemura

  379
  Citations

• Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8.

  F. Kukulski;S. A. Lévesque;É. G. Lavoie;J. Lecka

  363
  Citations

• Nucleoside Triphosphate diphosphohydrolase-2 Is the ecto-ATPase of Type I Cells in Taste Buds

  Dianna L. Bartel;Susan L. Sullivan;Élise G. Lavoie;Jean Sévigny

  304
  Citations

• Targeted Disruption of cd73/Ecto-5′-Nucleotidase Alters Thromboregulation and Augments Vascular Inflammatory Response

  Patrycja Koszalka;Burcin Özüyaman;Yuqing Huo;Alma Zernecke

  301
  Citations

• CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease

  David J. Friedman;Beat M. Künzli;Yousif I. A-Rahim;Jean Sevigny

  288
  Citations

• Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation

  Jean Sévigny;Christian Sundberg;Norbert Braun;Olaf Guckelberger

  252
  Citations

• Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation

  Santosh K Mishra;Norbert Braun;Varsha Shukla;Marc Füllgrabe

  245
  Citations

• Specificity of the ecto‐ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases

  S A Lévesque;É G Lavoie;J Lecka;F Bigonnesse

  235
  Citations

• Ca2+ Responses in Enteric Glia Are Mediated by Connexin-43 Hemichannels and Modulate Colonic Transit in Mice

  Jonathon L. McClain;Vladimir Grubišić;David Fried;Roberto A. Gomez-Suarez;Roberto A. Gomez-Suarez

  213
  Citations

• The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse.

  Shinji Kataoka;Ruibiao Yang;Yoshiro Ishimaru;Yoshiro Ishimaru;Hiroaki Matsunami

  208
  Citations

• Ecto-5′-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A2A Receptor Functions

  Elisabete Augusto;Marco Matos;Marco Matos;Jean Sévigny;Ali El-Tayeb

  203
  Citations

• Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain.

  Norbert Braun;Jean Sévigny;Santosh K. Mishra;Simon C. Robson

  200
  Citations

• Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8.

  Francois Bigonnesse;Sébastien A. Levesque;Filip Kukulski;Joanna Lecka

  192
  Citations

• Assignment of ecto-nucleoside triphosphate diphosphohydrolase-1/cd39 expression to microglia and vasculature of the brain

  Norbert Braun;Jean Sévigny;Simon C. Robson;Keiichi Enjyoji

  192
  Citations

• P2Y6 Nucleotide Receptor Mediates Monocyte Interleukin-8 Production in Response to UDP or Lipopolysaccharide

  Michel Warny;Samer Aboudola;Simon C. Robson;Jean Sévigny

  188
  Citations