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Rodrigo A. Cunha

Rodrigo A. Cunha

D-Index & Metrics

Medicine

D-Index
98
Citations
29641
World Ranking
9018
National Ranking
8

Overview

Rodrigo A. Cunha is affiliated with the University of Coimbra in Portugal and has a substantial body of research primarily concentrated in the fields of Neuroscience, Medicine, and Biochemistry, Genetics and Molecular Biology. Their research spans further into the subfields of Physiology, Cellular and Molecular Neuroscience, Neurology, Pharmacology, and Molecular Biology.

The scientist's work focuses extensively on topics related to Adenosine and Purinergic Signaling, Neuroscience and Neuropharmacology Research, Neuroinflammation and Neurodegeneration Mechanisms, Vagus Nerve Stimulation Research, Tryptophan and brain disorders, Alzheimer's disease research and treatments, and Cannabis and Cannabinoid Research.

Rodrigo A. Cunha has been published frequently in several scientific venues. The most common of these venues include:

  • Purinergic Signalling
  • International Journal of Molecular Sciences
  • Molecular Neurobiology
  • European Journal of Neuroscience
  • IBRO Neuroscience Reports

The researcher has collaborated multiple times with a group of frequent co-authors, including:

  • Paula M. Canas (26 publications)
  • Paula Agostinho (24 publications)
  • Ângelo R. Tomé (24 publications)
  • Henrique B. Silva (19 publications)
  • Cátia R. Lopes (18 publications)

Some recent papers from Rodrigo A. Cunha illustrate key areas of focus and the impact of their research:

  • The belated US FDA approval of the adenosine A2A receptor antagonist istradefylline for treatment of Parkinson's disease, 2020, Purinergic Signalling
  • International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update, 2022, Pharmacological Reviews
  • Control of glutamate release by complexes of adenosine and cannabinoid receptors, 2020, BMC Biology
  • Purinergic signaling orchestrating neuron-glia communication, 2020, Pharmacological Research
  • Convergence of adenosine and GABA signaling for synapse stabilization during development, 2021, Science

Best Publications

  • Adenosine and Brain Function

    Bertil B Fredholm;Jiang-Fan Chen;Rodrigo A Cunha;Per Svenningsson

  • Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors

    R.A. Cunha

  • Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease.

    Paula Agostinho;Rodrigo A. Cunha;Catarina Oliveira

  • Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

    Francisco Ciruela;Vicent Casadó;Ricardo J. Rodrigues;Rafael Luján

  • Neuroprotection by adenosine in the brain: From A1 receptor activation to A2A receptor blockade

    Rodrigo A. Cunha

  • Adenosine receptors and brain diseases: neuroprotection and neurodegeneration.

    Catarina V. Gomes;Manuella P. Kaster;Angelo R. Tomé;Paula M. Agostinho

  • How does adenosine control neuronal dysfunction and neurodegeneration

    Rodrigo A. Cunha

  • Adenosine A2A receptors and basal ganglia physiology.

    Serge N. Schiffmann;Gilberto Fisone;R Moresco;Rodrigo Antunes Cunha

  • Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses.

    Nelson Rebola;Rafael Lujan;Rodrigo A. Cunha;Christophe Mulle

  • Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice.

    Oscar P. Dall'Igna;Paulo Fett;Marcio W. Gomes;Diogo O. Souza

  • Adenosine A2A Receptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by β-Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway

    Paula M. Canas;Lisiane O. Porciúncula;Geanne M. A. Cunha;Carla G. Silva

  • Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

    Manuella P. Kaster;Manuella P. Kaster;Nuno J. Machado;Henrique B. Silva;Ana Nunes

  • Neuroprotection by caffeine and adenosine A2A receptor blockade of β-amyloid neurotoxicity

    Oscar P Dall'Igna;Lisiane O Porciúncula;Diogo O Souza;Rodrigo A Cunha

  • Preferential Release of ATP and Its Extracellular Catabolism as a Source of Adenosine upon High- but Not Low-Frequency Stimulation of Rat Hippocampal Slices

    Cunha Ra;Vizi Es;Ribeiro Ja;Sebastião Am

  • An Update on Adenosine A2A-Dopamine D2 Receptor Interactions: Implications for the Function of G Protein-Coupled Receptors

    Sergi Ferré;César Quiroz;A S Woods;Rodrigo Antunes Cunha

  • Evidence for functionally important adenosine A2a receptors in the rat hippocampus.

    R. A. Cunha;B. Johansson;I. Van Der Ploeg;A. M. Sebastiao

  • Adenosine A2A receptor facilitation of hippocampal synaptic transmission is dependent on tonic A1 receptor inhibition

    L.V. Lopes;R.A. Cunha;B. Kull;B.B. Fredholm

  • Chronic caffeine consumption prevents memory disturbance in different animal models of memory decline.

    Rodrigo A Cunha;Paula M Agostinho

  • Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia

    Catarina Gomes;Raquel Ferreira;Jimmy George;Rui Sanches

  • Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.

    Jan Benes;António Parada;Anabela A. Figueiredo;Paula C. Alves

Frequent Co-Authors

Paula Agostinho
Paula Agostinho University of Coimbra
Catarina R. Oliveira
Catarina R. Oliveira University of Coimbra
Ana M. Sebastião
Ana M. Sebastião University of Lisbon
Luísa V. Lopes
Luísa V. Lopes University of Lisbon
Jiang-Fan Chen
Jiang-Fan Chen Boston University
Francisco Ciruela
Francisco Ciruela University of Barcelona
António F. Ambrósio
António F. Ambrósio University of Coimbra
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse
João O. Malva
João O. Malva University of Coimbra
Christa E. Müller
Christa E. Müller University of Bonn

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