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Neuroscience

D-Index
80
Citations
18773
World Ranking
1646
National Ranking
804

Overview

Detlev Boison is affiliated with Rutgers, The State University of New Jersey in the United States. Their research spans multiple disciplines, primarily focusing on medicine, biochemistry, genetics and molecular biology, and neuroscience. Within these broad areas, their work delves into various subfields including physiology, molecular biology, psychiatry and mental health, cellular and molecular neuroscience, and neurology.

The scientist's research activities are centered on several main topics that reflect their diverse expertise. These include adenosine and purinergic signaling, neuroscience and neuropharmacology research, epilepsy research and treatment, epigenetics and DNA methylation, neuroscience of respiration and sleep, diet and metabolism studies, and mitochondrial function and pathology.

Key recent publications demonstrate the scope of their collaborative and interdisciplinary efforts. Notable papers include:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes, 2021, British Journal of Pharmacology
  • The Concise Guide to PHARMACOLOGY 2023/24: Enzymes, 2023, British Journal of Pharmacology
  • The metabolic basis of epilepsy, 2022, Nature Reviews Neurology
  • Astrocytes in the initiation and progression of epilepsy, 2022, Nature Reviews Neurology
  • Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice, 2022, Alzheimer's Research & Therapy

Boison frequently publishes in several scientific venues, with multiple contributions to Neuropharmacology, Pharmacological Reviews, the IUPHAR/BPS Guide to Pharmacology CITE, British Journal of Pharmacology, and Nature Reviews Neurology.

They have collaborated extensively with several coauthors, including Denise Fedele, Madhuvika Murugan, Benton S. Purnell, Enmar Alharfoush, and Xiongfei Wang.

Best Publications

  • Adenosine signaling and function in glial cells.

    Detlev Boison;Jiang-Fan Chen;Bertil B. Fredholm

  • Adenosine Kinase: Exploitation for Therapeutic Gain

    Detlev Boison

  • Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens

    Michael Lazarus;Hai Ying Shen;Yoan Cherasse;Wei Min Qu

  • Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice

    Tianfu Li;Gaoying Ren;Theresa Lusardi;Andrew Wilz

  • A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

    Susan A. Masino;Tianfu Li;Panos Theofilas;Ursula S. Sandau

  • Adenosine kinase, epilepsy and stroke: mechanisms and therapies

    Detlev Boison

  • Adenosine and Epilepsy: From Therapeutic Rationale to New Therapeutic Strategies

    Detlev Boison

  • Adenosine as a neuromodulator in neurological diseases

    Detlev Boison

  • The adenosine kinase hypothesis of epileptogenesis

    Detlev Boison

  • Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

    Pavel Klein;Raymond Dingledine;Eleonora Aronica;Christophe Bernard

  • Overexpression of Adenosine Kinase in Epileptic Hippocampus Contributes to Epileptogenesis

    Nicolette Gouder;Louis Scheurer;Jean Marc Fritschy;Detlev Boison;Detlev Boison

  • Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis

    Rebecca L. Williams-Karnesky;Ursula S. Sandau;Theresa A. Lusardi;Nikki K. Lytle

  • Seizure Suppression by Adenosine A1 Receptor Activation in a Mouse Model of Pharmacoresistant Epilepsy

    Nicolette Gouder;Jean Marc Fritschy;Detlev Boison;Detlev Boison

  • Neonatal hepatic steatosis by disruption of the adenosine kinase gene

    Detlev Boison;Louis Scheurer;Valérie Zumsteg;Thomas Rülicke

  • Astrocytes in the initiation and progression of epilepsy

    Unknown

  • Silk polymer-based adenosine release: therapeutic potential for epilepsy

    Detlev Boison;David L. Kaplan

  • Epilepsy and astrocyte energy metabolism

    Detlev Boison;Christian Steinhäuser

  • Adenosine dysfunction in epilepsy.

    Detlev Boison

  • Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation

    Denise E. Fedele;Nicolette Gouder;Martin Güttinger;Laetitia Gabernet

  • Adenosine A1 receptors are crucial in keeping an epileptic focus localized.

    Denise E. Fedele;Tianfu Li;Jing Q. Lan;Bertil B. Fredholm

  • Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy

    Alexander Huber;Vivianne Padrun;Nicole Déglon;Patrick Aebischer

  • A Critical Role of the Adenosine A2A Receptor in Extrastriatal Neurons in Modulating Psychomotor Activity as Revealed by Opposite Phenotypes of Striatum and Forebrain A2A Receptor Knock-Outs

    Hai Ying Shen;Joana E. Coelho;Nobuhisa Ohtsuka;Paula M. Canas

Frequent Co-Authors

Benjamin K. Yee
Benjamin K. Yee Hong Kong Polytechnic University
Joram Feldon
Joram Feldon ETH Zurich
Susan A. Masino
Susan A. Masino Trinity College
David L. Kaplan
David L. Kaplan Tufts University
Jiang-Fan Chen
Jiang-Fan Chen Boston University
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Roger P. Simon
Roger P. Simon Morehouse School of Medicine
David Blum
David Blum University of Lille
Ana M. Sebastião
Ana M. Sebastião University of Lisbon
Luísa V. Lopes
Luísa V. Lopes University of Lisbon

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Related Online Degrees & Career Pathways

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