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Leendert H. J. Looijenga

Leendert H. J. Looijenga

D-Index & Metrics

Medicine

D-Index
106
Citations
58275
World Ranking
6389
National Ranking
243

Overview

Leendert H. J. Looijenga is affiliated with the Princess Máxima Center in the Netherlands. Their research primarily centers on the molecular pathology and clinical management of urogenital cancers, with a focus on testicular germ cell tumors and associated biomarkers.

The scientist's recent publications include the following works:

  • "Circulating MicroRNAs, the Next-Generation Serum Biomarkers in Testicular Germ Cell Tumours: A Systematic Review" (2021) published in European Urology
  • "Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours" (2020) published in Nature Reviews Urology
  • "Utility of Serum miR-371a-3p in Predicting Relapse on Surveillance in Patients with Clinical Stage I Testicular Germ Cell Cancer" (2020) published in European Urology Oncology
  • "Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers" (2020) published in The American Journal of Surgical Pathology
  • "The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors" (2021) published in Journal of Experimental & Clinical Cancer Research

Frequent co-authors collaborating with Looijenga include:

  • Ad Gillis
  • João Lobo
  • Annelies M. C. Mavinkurve-Groothuis
  • Thomas F. Eleveld
  • Caroline C. C. Hulsker

The scientist's work has been published extensively in various venues, with notable frequent publications in:

  • Cancers
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Precision Oncology
  • Cancer Medicine

The primary fields of study covered by Leendert H. J. Looijenga's research include Medicine and Biochemistry, Genetics and Molecular Biology. Their investigations delve into several subfields, such as:

  • Molecular Biology
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Genetics
  • Cancer Research

The main topics addressed in this research focus on clinical and molecular aspects of testicular diseases and treatments, as well as other related areas:

  • Testicular diseases and treatments
  • Sarcoma Diagnosis and Treatment
  • Sexual Differentiation and Disorders
  • Renal and related cancers
  • Epigenetics and DNA Methylation
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Pluripotent Stem Cells Research

Best Publications

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

    P Mathijs Voorhoeve;Carlos le Sage;Mariette Schrier;Ad J M Gillis

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Testicular germ-cell tumours in a broader perspective.

    J. Wolter Oosterhuis;Leendert H. J. Looijenga

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Lung cancer: intragenic ERBB2 kinase mutations in tumours.

    Philip Stephens;Chris Hunter;Graham Bignell;Sarah Edkins

  • POU5F1 (OCT3/4) Identifies Cells with Pluripotent Potential in Human Germ Cell Tumors

    Leendert H. J. Looijenga;Hans Stoop;Hubert P. J. C. de Leeuw;Carlos A. de Gouveia Brazao

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Somatic Mutations of the Protein Kinase Gene Family in Human Lung Cancer

    Helen Davies;Chris Hunter;Raffaella Smith;Philip Stephens

  • Germ cell tumors in the intersex gonad: old paths, new directions, moving frontiers.

    Martine Cools;Stenvert L. S. Drop;Katja P. Wolffenbuttel;J. Wolter Oosterhuis

  • National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers

    Catharine M. Sturgeon;Michael J. Duffy;Ulf Håkan Stenman;Hans Lilja

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

    Philip Stephens;Sarah Edkins;Helen Davies;Christopher Greenman

  • Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas.

    Dan Qiao;Anne-Marie Zeeman;Wei Deng;Leendert H J Looijenga

  • Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort

    Stefanie Eggers;Simon Sadedin;Jocelyn A. van den Bergen;Gorjana Robevska

  • Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells

    Friedemann Honecker;Friedemann Honecker;Hans Stoop;Ronald R. De Krijger;Yun-Fai Chris Lau

Frequent Co-Authors

Marco J. Bruno
Marco J. Bruno Erasmus University Rotterdam
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Ewout W. Steyerberg
Ewout W. Steyerberg Leiden University Medical Center
Ad Geurts van Kessel
Ad Geurts van Kessel Radboud University
Andrew H. Sinclair
Andrew H. Sinclair University of Melbourne
Arndt Hartmann
Arndt Hartmann University of Erlangen-Nuremberg
Martin F. Pera
Martin F. Pera Walter and Eliza Hall Institute of Medical Research
Rui Henrique
Rui Henrique University of Porto
Carmen Jerónimo
Carmen Jerónimo University of Porto
Mark A. Rubin
Mark A. Rubin University of Bern

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