World's Best Scientists 2026 revealed!
Yoshihiro Urade

Yoshihiro Urade

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
31106
World Ranking
1915
National Ranking
107

Medicine

D-Index
96
Citations
31551
World Ranking
9736
National Ranking
270

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Yoshihiro Urade is affiliated with the University of Tsukuba in Japan and has contributed extensively to the fields of Medicine and Neuroscience. Their research spans 43 publications in Medicine and 19 in Neuroscience, with significant focus on subfields such as Cardiology and Cardiovascular Medicine, Molecular Biology, Ophthalmology, Neurology, and Immunology.

Their work covers various key research topics including:

  • Inflammatory mediators and NSAID effects
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and neurodegeneration mechanisms
  • Circadian rhythm and melatonin
  • Eicosanoids and hypertension pharmacology
  • Ocular diseases and Behçet's Syndrome
  • Retinal diseases and treatments

Some of their recent papers include:

  • "Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2" (2020), published in Gastroenterology
  • "Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages" (2020), published in Circulation Research
  • "Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin" (2021), published in Frontiers in Physiology
  • "Analysis of inflammatory mediators in the vitreous humor of eyes with pan-uveitis according to aetiological classification" (2020), published in Scientific Reports
  • "Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination" (2023), published in eLife

Yoshihiro Urade often collaborates with several frequent coauthors, including:

  • Youichiro Wada
  • Takashi Shimizu
  • Kosuke Aritake
  • Yasuharu Kanki
  • Toshikatsu Kaburaki

Their work appears regularly in well-known publication venues, notably:

  • Scientific Reports
  • SLEEP
  • UNC Libraries
  • SSRN Electronic Journal
  • Gastroenterology

Best Publications

  • Prostaglandin D2 as a Mediator of Allergic Asthma

    Toshiyuki Matsuoka;Masakazu Hirata;Hiroyuki Tanaka;Yoshimasa Takahashi

  • Arousal effect of orexin A depends on activation of the histaminergic system

    Zhi-Li Huang;Wei-Min Qu;Wei-Dong Li;Takatoshi Mochizuki

  • Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

    Zhi-Li Huang;Wei-Min Qu;Naomi Eguchi;Jiang-Fan Chen

  • Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

    William L. Smith;Yoshihiro Urade;Per Johan Jakobsson

  • Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase.

    Yoshihiro Urade;Osamu Hayaishi

  • Prostaglandin D synthase: structure and function.

    Yoshihiro Urade;Osamu Hayaishi

  • A toxic monomeric conformer of the polyglutamine protein.

    Yoshitaka Nagai;Takashi Inui;Takashi Inui;Takashi Inui;H Akiko Popiel;Nobuhiro Fujikake

  • Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats

    Mayumi Ujihara;Yoshihiro Urade;Naomi Eguchi;Hideya Hayashi

  • miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

    Rikako Sanuki;Akishi Onishi;Chieko Koike;Rieko Muramatsu

  • An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons

    T.E Scammell;D.Y Gerashchenko;T Mochizuki;M.T McCarthy

  • Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens

    Michael Lazarus;Hai Ying Shen;Yoan Cherasse;Wei Min Qu

  • Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice.

    Yasushi Fujitani;Yoshihide Kanaoka;Kosuke Aritake;Nobuko Uodome

  • Cloning and crystal structure of hematopoietic prostaglandin D synthase.

    Yoshihide Kanaoka;Hideo Ago;Eiji Inagaki;Toyomichi Nanayama

  • Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice

    Naomi Eguchi;Toshiaki Minami;Naoki Shirafuji;Yoshihide Kanaoka

  • The major source of endogenous prostaglandin D2 production is likely antigen-presenting cells. Localization of glutathione-requiring prostaglandin D synthetase in histiocytes, dendritic, and Kupffer cells in various rat tissues.

    Y Urade;M Ujihara;Y Horiguchi;K Ikai

  • Lipocalin-type Prostaglandin D Synthase (β-Trace) Is a Newly Recognized Type of Retinoid Transporter

    Toshiki Tanaka;Yoshihiro Urade;Hiromi Kimura;Naomi Eguchi

  • Dopaminergic D1 and D2 Receptors Are Essential for the Arousal Effect of Modafinil

    Wei-Min Qu;Zhi-Li Huang;Xin-Hong Xu;Naomi Matsumoto

  • Prostaglandins and adenosine in the regulation of sleep and wakefulness

    Zhi-Li Huang;Yoshihiro Urade;Osamu Hayaishi

  • Coupling between cyclooxygenase, terminal prostanoid synthase, and phospholipase A2.

    Noriko Ueno;Makoto Murakami;Toshihiro Tanioka;Ko Fujimori

  • Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection

    Ryotaro Yoshida;Yoshihiro Urade;Masao Tokuda;Osamu Hayaishi

Frequent Co-Authors

Osamu Hayaishi
Osamu Hayaishi Osaka Bioscience Institute
Zhi-Li Huang
Zhi-Li Huang Fudan University
Michael Lazarus
Michael Lazarus University of Tsukuba
Yoshihide Kanaoka
Yoshihide Kanaoka Brigham and Women's Hospital
Tsuyoshi Inoue
Tsuyoshi Inoue Osaka University
Shuh Narumiya
Shuh Narumiya Kyoto University
Takatoshi Mochizuki
Takatoshi Mochizuki Beth Israel Deaconess Medical Center
Jiang-Fan Chen
Jiang-Fan Chen Boston University
Takeshi Kaneko
Takeshi Kaneko Kyoto University
Masatoshi Hori
Masatoshi Hori University of Tokyo

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