World's Best Scientists 2026 revealed!
Shuh Narumiya

Shuh Narumiya

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Best Scientists
2025
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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Best Scientists

D-Index
169
Citations
103650
World Ranking
916
National Ranking
15

Biology and Biochemistry

D-Index
171
Citations
106244
World Ranking
86
National Ranking
1

Medicine

D-Index
171
Citations
104183
World Ranking
509
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2026 - Research.com Medicine in Japan Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Medicine in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2022 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Shuh Narumiya is affiliated with Kyoto University in Japan and has contributed extensively to research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans various subfields including Immunology, Molecular Biology, Pharmacology, Oncology, and Surgery.

The research topics covered by Shuh Narumiya focus on inflammatory mediators and NSAID effects, immune cell function and interaction, cell adhesion molecules research, the lymphatic system and diseases, eicosanoids and hypertension pharmacology, immune cells in cancer, and cancer immunotherapy and biomarkers.

They have published multiple papers in a range of scientific venues. Some recent notable publications include:

  • Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19, 2022, Nature
  • PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment, 2022, Cell Reports
  • Prostaglandin E 2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells, 2021, Science Advances
  • Role of JAK-STAT signaling in the pathogenic behavior of fibroblast-like synoviocytes in rheumatoid arthritis: Effect of the novel JAK inhibitor peficitinib, 2020, European Journal of Pharmacology
  • LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation, 2022, Proceedings of the National Academy of Sciences

Frequent publication venues for their work include:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • IUPHAR/BPS Guide to Pharmacology CITE
  • Science Advances
  • Cardiovascular Research

Shuh Narumiya has collaborated frequently with a number of researchers, with the most frequent co-authors being:

  • Dean Thumkeo
  • Masataka Majima
  • Yoshiya Ito
  • Chengcan Yao
  • Kanako Hosono

Best Publications

  • Prostanoid Receptors: Structures, Properties, and Functions

    Shuh Narumiya;Yukihiko Sugimoto;Fumitaka Ushikubi

  • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

    Masayoshi Uehata;Toshimasa Ishizaki;Hiroyuki Satoh;Takashi Ono

  • International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.

    Robert A. Coleman;William L. Smith;Shuh Narumiya

  • CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

    Yoshiya Kawaguchi;Toshihiro Okamoto;Masafumi Taniwaki;Megumi Aizawa

  • Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

    Midori Maekawa;Toshimasa Ishizaki;Shuken Boku;Naoki Watanabe

  • Focal Contacts as Mechanosensors Externally Applied Local Mechanical Force Induces Growth of Focal Contacts by an Mdia1-Dependent and Rock-Independent Mechanism

    Daniel Riveline;Daniel Riveline;Eli Zamir;Nathalie Q. Balaban;Ulrich S. Schwarz

  • Prostaglandin E Receptors

    Yukihiko Sugimoto;Shuh Narumiya

  • Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases.

    Toshimasa Ishizaki;Masayoshi Uehata;Ichiro Tamechika;Jeongsin Keel

  • The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

    Toshimasa Ishizaki;Midori Maekawa;Kazuko Fujisawa;Katsuya Okawa

  • Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

    Naoki Watanabe;Takayuki Kato;Akiko Fujita;Toshimasa Ishizaki

  • Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

    Atsushi Mikami;Keiji Imoto;Tsutomu Tanabe;Tetsuhiro Niidome

  • p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.

    Naoki Watanabe;Pascal Madaule;Tim Reid;Toshimasa Ishizaki

  • Prostaglandin D2 as a Mediator of Allergic Asthma

    Toshiyuki Matsuoka;Masakazu Hirata;Hiroyuki Tanaka;Yoshimasa Takahashi

  • ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

    Osamu Nakagawa;Kazuko Fujisawa;Toshimasa Ishizaki;Yuji Saito

  • Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

    Takahiko Murata;Fumitaka Ushikubi;Toshiyuki Matsuoka;Masakazu Hirata

  • Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3.

    Fumitaka Ushikubi;Eri Segi;Yukihiko Sugimoto;Takahiko Murata

  • An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

    Kazuyuki Itoh;Kiyoko Yoshioka;Hitoshi Akedo;Masayoshi Uehata

  • Cloning and expression of cDNA for a human thromboxane A2 receptor

    Masakazu Hirata;Yasunori Hayashi;Fumitaka Ushikubi;Yoshifumi Yokota

  • Failure of Parturition in Mice Lacking the Prostaglandin F Receptor

    Yukihiko Sugimoto;Atsushi Yamasaki;Eri Segi;Kazuhito Tsuboi

  • Expanded polyglutamine in the machado-joseph disease protein induces cell death in vitro and in vivo

    Hanako Ikeda;Masahiro Yamaguchi;Satoshi Sugai;Yoshiya Aze

Frequent Co-Authors

Yukihiko Sugimoto
Yukihiko Sugimoto Kumamoto University
Toshimasa Ishizaki
Toshimasa Ishizaki Oita University
Atsushi Ichikawa
Atsushi Ichikawa Mukogawa Women's University
Akira Kakizuka
Akira Kakizuka Kyoto University
Kenji Kabashima
Kenji Kabashima Kyoto University
Sylvain Doré
Sylvain Doré University of Florida
Toru Kita
Toru Kita Kyoto University
Haruhiko Bito
Haruhiko Bito University of Tokyo
Kazuwa Nakao
Kazuwa Nakao Kyoto University
Yoshihiro Urade
Yoshihiro Urade University of Tsukuba

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