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Yukihiko Sugimoto

Yukihiko Sugimoto

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
37254
World Ranking
2399
National Ranking
147

Overview

Yukihiko Sugimoto is affiliated with Kumamoto University in Japan. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable subfields that include Pharmacology, Biochemistry, Genetics, Molecular Biology, and Physiology.

The scientist's work focuses on several key topics:

  • Inflammatory mediators and NSAID effects
  • Estrogen and related hormone effects
  • Eicosanoids and Hypertension Pharmacology
  • Fatty Acid Research and Health
  • Asthma and respiratory diseases
  • Reproductive System and Pregnancy
  • Neuroendocrine regulation and behavior

Recent scholarly contributions include research published in leading journals featuring the following papers:

  • Prostaglandin E2-EP4 Axis Promotes Lipolysis and Fibrosis in Adipose Tissue Leading to Ectopic Fat Deposition and Insulin Resistance, 2020, Cell Reports
  • International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions, 2020, Pharmacological Reviews
  • Effects of the Selective EP2 Receptor Agonist Omidenepag on Adipocyte Differentiation in 3T3-L1 Cells, 2020, Journal of Ocular Pharmacology and Therapeutics
  • Induced Prostanoid Synthesis Regulates the Balance between Th1- and Th2-Producing Inflammatory Cytokines in the Thymus of Diet-Restricted Mice, 2020, Biological and Pharmaceutical Bulletin
  • Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation, 2020, Cellular and Molecular Immunology

Frequent co-authors collaborating with Yukihiko Sugimoto include:

  • Tomoaki Inazumi
  • Soken Tsuchiya
  • Xavier Norel
  • Ákos Heinemann
  • Chengcan Yao

Their research has been published repeatedly in several specialized venues, including:

  • Biological and Pharmaceutical Bulletin
  • Communications Biology
  • Journal of Natural Products
  • Kidney360
  • IUPHAR/BPS Guide to Pharmacology CITE

Best Publications

  • Prostanoid Receptors: Structures, Properties, and Functions

    Shuh Narumiya;Yukihiko Sugimoto;Fumitaka Ushikubi

  • Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.

    Akira Hirasawa;Keiko Tsumaya;Takeo Awaji;Susumu Katsuma

  • Prostaglandin E Receptors

    Yukihiko Sugimoto;Shuh Narumiya

  • Prostaglandin D2 as a Mediator of Allergic Asthma

    Toshiyuki Matsuoka;Masakazu Hirata;Hiroyuki Tanaka;Yoshimasa Takahashi

  • Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

    Takahiko Murata;Fumitaka Ushikubi;Toshiyuki Matsuoka;Masakazu Hirata

  • Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3.

    Fumitaka Ushikubi;Eri Segi;Yukihiko Sugimoto;Takahiko Murata

  • Failure of Parturition in Mice Lacking the Prostaglandin F Receptor

    Yukihiko Sugimoto;Atsushi Yamasaki;Eri Segi;Kazuhito Tsuboi

  • Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity.

    Tsunehisa Namba;Yukihiko Sugimoto;Manabu Negishi;Atsushi Irie

  • Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.

    Michitaka Kiriyama;Fumitaka Ushikubi;Takuya Kobayashi;Masakazu Hirata

  • Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion.

    Chengcan Yao;Chengcan Yao;Daiji Sakata;Yoshiyasu Esaki;Youxian Li

  • Acceleration of intestinal polyposis through prostaglandin receptor EP2 in ApcΔ716 knockout mice

    Masahiro Sonoshita;Kazuaki Takaku;Kazuaki Takaku;Nobuya Sasaki;Yukihiko Sugimoto

  • Sensitization of TRPV1 by EP1 and IP Reveals Peripheral Nociceptive Mechanism of Prostaglandins

    Tomoko Moriyama;Tomoko Moriyama;Tomohiro Higashi;Tomohiro Higashi;Kazuya Togashi;Kazuya Togashi;Tohko Iida

  • Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP2

    Hiroko Hizaki;Eri Segi;Yukihiko Sugimoto;Masaya Hirose;Masaya Hirose

  • The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs.

    Tetsuo Suzawa;Chisato Miyaura;Masaki Inada;Takayuki Maruyama

  • Molecular mechanisms of diverse actions of prostanoid receptors

    Manabu Negishi;Yukihiko Sugimoto;Atsushi Ichikawa

  • The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut

    Kenji Kabashima;Tomomi Saji;Takahiko Murata;Miyako Nagamachi

  • Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors.

    Kohichi Kawahara;Hirofumi Hohjoh;Tomoaki Inazumi;Soken Tsuchiya

  • Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

    Akiko Honda;Yukihiko Sugimoto;Tsunehisa Namba;Akiko Watabe

  • Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation

    Keiji Yoshida;Hiroji Oida;Takuya Kobayashi;Takayuki Maruyama

  • Host Prostaglandin E2-EP3 Signaling Regulates Tumor-Associated Angiogenesis and Tumor Growth

    Hideki Amano;Izumi Hayashi;Hirahito Endo;Hidero Kitasato

Frequent Co-Authors

Atsushi Ichikawa
Atsushi Ichikawa Mukogawa Women's University
Shuh Narumiya
Shuh Narumiya Kyoto University
Manabu Negishi
Manabu Negishi Kyoto University
Kenji Kabashima
Kenji Kabashima Kyoto University
Gozoh Tsujimoto
Gozoh Tsujimoto Kyoto University
Nobuaki Yoshida
Nobuaki Yoshida University of Tokyo
Akira Kakizuka
Akira Kakizuka Kyoto University
Makoto Murakami
Makoto Murakami University of Tokyo
Takehiko Yokomizo
Takehiko Yokomizo Juntendo University
Hitoshi Hashimoto
Hitoshi Hashimoto Osaka University

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