World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
97
Citations
43300
World Ranking
1727
National Ranking
960

Medicine

D-Index
97
Citations
43310
World Ranking
9144
National Ranking
4717

Overview

Beverly H. Koller is a researcher affiliated with the University of North Carolina at Chapel Hill in the United States. Their academic focus spans multiple fields within the life sciences, primarily Biochemistry, Genetics and Molecular Biology, and Medicine. Their work is notably concentrated in subfields including Molecular Biology, Immunology, Physiology, Pharmacology, and Infectious Diseases.

Throughout their career, Koller has contributed extensively to the understanding of immune mechanisms and disease processes. The scientist's research themes include inflammasome and immune disorders, inflammatory mediators and NSAID effects, as well as asthma and respiratory diseases. Additional topics addressed in their publications are arsenic contamination and mitigation, adenosine and purinergic signaling, SARS-CoV-2 and COVID-19 research, and heavy metal exposure and toxicity.

Key scientific articles authored or coauthored by Beverly H. Koller include:

  • Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice, 2021, Nature Communications
  • Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement, 2020, Environmental Health Perspectives
  • Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium, 2024, Science Immunology
  • Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements, 2023, PLoS Pathogens
  • Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases, 2024, Cell Reports

Koller frequently collaborates with several researchers across their projects. Notable frequent coauthors include John N. Snouwaert, Leigh A. Jania, MyTrang Nguyen, Sheryl S. Moy, and Martina Kovářová.

The primary venues where Koller's research has been published reflect a diverse engagement with both institutional and disciplinary journals. The most common publication venues are UNC Libraries, Environmental Health Perspectives, Nature Communications, Science Immunology, and PLoS Pathogens.

Best Publications

  • Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production.

    Krisztián Németh;Asada Leelahavanichkul;Peter S T Yuen;Balázs Mayer

  • Brca1 controls homology-directed DNA repair.

    Mary Ellen Moynahan;Joanne W Chiu;Beverly H Koller;Maria Jasin

  • The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

    Jeffrey Leonard Staudinger;Jeffrey Leonard Staudinger;Bryan Goodwin;Stacey A. Jones;Diane Hawkins-Brown

  • Altered Cytokine Production in Mice Lacking P2X7Receptors

    Mike Solle;Jeff Labasi;David G. Perregaux;Ethan Stam

  • Mice with Reduced NMDA Receptor Expression Display Behaviors Related to Schizophrenia

    Amy R Mohn;Raul R Gainetdinov;Marc G Caron;Beverly H Koller

  • Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells

    Beverly H. Koller;Philippa Marrack;John W. Kappler;Oliver Smithies

  • An Animal Model for Cystic Fibrosis Made by Gene Targeting

    John N. Snouwaert;Kristen K. Brigman;Anne M. Latour;Nadia N. Malouf

  • Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

    Stephen L. Tilley;Thomas M. Coffman;Beverly H. Koller

  • Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.

    Joanne L. Flynn;Marsha M. Goldstein;Karla J. Triebold;Beverly Koller

  • Role of Prostacyclin in the Cardiovascular Response to Thromboxane A2

    Yan Cheng;Sandra C. Austin;Bianca Rocca;Beverly H. Koller

  • The knockout mouse project

    Christopher P. Austin;James F. Battey;Allan Bradley;Maja Bucan

  • The Breast Cancer Susceptibility Gene BRCA1 Is Required for Subnuclear Assembly of Rad51 and Survival following Treatment with the DNA Cross-linking Agent Cisplatin

    Anamitra Bhattacharyya;Uy S. Ear;Beverly H. Koller;Ralph R. Weichselbaum

  • Homologous recombination for universal donor cells and chimeric mammalian hosts

    Raju S. Kucherlapati;Beverly H. Koller;Oliver Smithies

  • BRCA1 Required for Transcription-Coupled Repair of Oxidative DNA Damage

    Lori C. Gowen;Anna V. Avrutskaya;Anne M. Latour;Beverly H. Koller

  • Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model

    SE Gabriel;KN Brigman;BH Koller;RC Boucher

  • A HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GENE THAT ENCODES A PROTEIN WITH A SHORTENED CYTOPLASMIC SEGMENT

    Daniel E. Geraghty;Beverly H. Koller;Harry T. Orr

  • Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities.

    L C Gowen;B L Johnson;A M Latour;K K Sulik

  • Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.

    Jean Etienne Fabre;Mytrang Nguyen;Anne Latour;Jayne A. Keifer

  • COX-2-Derived Prostacyclin Confers Atheroprotection on Female Mice

    Karine M. Egan;John A. Lawson;Susanne Fries;Beverly H Koller

  • The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth

    My Trang Nguyen;Todd Camenisch;John N. Snouwaert;Elizabeth Hicks

Frequent Co-Authors

Thomas M. Coffman
Thomas M. Coffman Duke University
Sheryl S. Moy
Sheryl S. Moy University of North Carolina at Chapel Hill
Oliver Smithies
Oliver Smithies University of North Carolina at Chapel Hill
Harry T. Orr
Harry T. Orr University of Minnesota
Gary E. Duncan
Gary E. Duncan University of North Carolina at Chapel Hill
Jenny P.-Y. Ting
Jenny P.-Y. Ting University of North Carolina at Chapel Hill
Daniel E. Geraghty
Daniel E. Geraghty Fred Hutchinson Cancer Research Center
Richard C. Boucher
Richard C. Boucher University of North Carolina at Chapel Hill
Garret A. FitzGerald
Garret A. FitzGerald University of Pennsylvania
Oliver Smithies
Oliver Smithies University of North Carolina at Chapel Hill

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