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Immunology

D-Index
72
Citations
17507
World Ranking
2233
National Ranking
1079

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Rick L. Tarleton is affiliated with the University of Georgia in the United States and focuses primarily on the field of Medicine, with a significant concentration on Epidemiology, Public Health, Environmental and Occupational Health, Parasitology, Infectious Diseases, and Organic Chemistry.

The main topics of their research include Trypanosoma species research and implications, research on Leishmaniasis studies, synthesis and biological evaluation, parasitic infections and diagnostics, insect symbiosis and bacterial influences, parasites and host interactions, and immune cell function and interaction.

Their research has been published in various venues, with frequent publications in bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, PLoS neglected tropical diseases, Antimicrobial Agents and Chemotherapy, and eLife.

Recent papers authored or co-authored by Rick L. Tarleton include:

  • Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease, 2021, PLoS Pathogens
  • Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates, 2022, Nature Microbiology
  • A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease, 2020, Science Translational Medicine
  • New Scheme of Intermittent Benznidazole Administration in Patients Chronically Infected with Trypanosoma cruzi: Clinical, Parasitological, and Serological Assessment after Three Years of Follow-Up, 2020, Antimicrobial Agents and Chemotherapy
  • High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA, 2021, PLoS neglected tropical diseases

The scientist collaborates frequently with a set of co-authors, including Sarah A. Hamer, Brooke E. White, Ashley B. Saunders, Ángel M. Padilla, and Susana A. Laucella.

Rick L. Tarleton has received recognition from professional organizations, notably being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • Kinetoplastids: related protozoan pathogens, different diseases

    Ken Stuart;Reto Brun;Simon Croft;Alan Fairlamb

  • Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection

    R. L. Tarleton;Beverly H Koller;A. Latour;M. Postan

  • Parasite persistence in the aetiology of Chagas disease.

    Rick L. Tarleton

  • Parasite Persistence Correlates with Disease Severity and Localization in Chronic Chagas' Disease

    L. Zhang;R. L. Tarleton

  • Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR

    Kara L. Cummings;Rick L. Tarleton

  • Chagas Disease Etiology: Autoimmunity or Parasite Persistence?

    R.L Tarleton;L Zhang

  • Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi.

    R L Tarleton

  • The challenges of Chagas Disease-- grim outlook or glimmer of hope.

    Rick L Tarleton;Richard Reithinger;Julio A Urbina;Uriel Kitron

  • CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

    Diana L Martin;D. Brent Weatherly;Susana A Laucella;Melissa A Cabinian

  • Immune system recognition of Trypanosoma cruzi.

    Rick L. Tarleton

  • Frequency of Interferon-γ-Producing T Cells Specific for Trypanosoma cruzi Inversely Correlates with Disease Severity in Chronic Human Chagas Disease

    Susana A. Laucella;Miriam Postan;Diana Martin;Bolyn Hubby Fralish

  • Chagas disease: a role for autoimmunity?

    Rick L. Tarleton

  • Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

    Juan M Bustamante;Lisa M Bixby;Rick L Tarleton

  • Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease.

    R. L. Tarleton;Jiaren Sun;L. Zhang;M. Postan

  • Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease

    Rick L. Tarleton;Michael J. Grusby;Miriam Postan;Laurie H. Glimcher

  • The relative contribution of antibody production and CD8 ˛ T cell function to immune control of Trypanosoma cruzi

    Sudesh Kumar;Rick L Tarleton

  • Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection.

    Diana Martin;Rick Tarleton

  • Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients.

    María Cecilia Albareda;Susana Adriana Laucella;María Gabriela Alvarez;Alejandro Hector Armenti

  • "Autoimmune rejection" of neonatal heart transplants in experimental Chagas disease is a parasite-specific response to infected host tissue.

    R. L. Tarleton;L. Zhang;M. O. Downs

  • Identification of Trypanosoma cruzi trans-sialidase family members as targets of protective CD8+ TC1 responses.

    B Wizel;M Nunes;R L Tarleton

  • In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds.

    Adriana M. C. Canavaci;Juan M. Bustamante;Angel M. Padilla;Cecilia M. Perez Brandan

Frequent Co-Authors

Amit P. Sheth
Amit P. Sheth University of South Carolina
Ron Orlando
Ron Orlando University of Georgia
Ricardo E. Gürtler
Ricardo E. Gürtler University of Buenos Aires
Jessica C. Kissinger
Jessica C. Kissinger University of Georgia
Julio A. Urbina
Julio A. Urbina Instituto Venezolano de Investigaciones Científicas
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Michael J. Grusby
Michael J. Grusby Harvard University
Kenneth Stuart
Kenneth Stuart University of Washington
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Mariano J. Levin
Mariano J. Levin University of Buenos Aires

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