What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
Immunology, Cell biology, Molecular biology, Transcription factor and Interleukin 21 are his primary areas of study.
Michael J. Grusby works mostly in the field of Immunology, limiting it down to topics relating to Signal transduction and, in certain cases, STAT6 and Receptor.
As a member of one scientific family, Michael J. Grusby mostly works in the field of Cell biology, focusing on CD40 and, on occasion, Antibody.
His study on Molecular biology also encompasses disciplines like
- Major histocompatibility complex, which have a strong connection to Antigen presentation and In vivo,
- Cell surface receptor, Immune system and Mutant most often made with reference to Gene targeting.
The Transcription factor study combines topics in areas such as STAT4, Cellular differentiation, Cytokine, Progenitor cell and Hepatocyte.
His Interleukin 21 research integrates issues from Interleukin 12 and IL-2 receptor.
His most cited work include:
- Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells (1410 citations)
- Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice (1168 citations)
- Plasma cell differentiation requires the transcription factor XBP-1 (1055 citations)
What are the main themes of his work throughout his whole career to date?
Michael J. Grusby mainly investigates Immunology, Molecular biology, Cell biology, T cell and Cytotoxic T cell.
His Immunology study frequently draws connections to adjacent fields such as STAT4.
As a part of the same scientific family, Michael J. Grusby mostly works in the field of Molecular biology, focusing on Regulation of gene expression and, on occasion, T helper cell.
His Cell biology study combines topics from a wide range of disciplines, such as Transcription factor, Cellular differentiation, Cell growth and CD40.
Michael J. Grusby interconnects Lipase and Gene in the investigation of issues within Cytotoxic T cell.
His Major histocompatibility complex study incorporates themes from Autoimmunity and CD8.
He most often published in these fields:
- Immunology (49.40%)
- Molecular biology (34.34%)
- Cell biology (31.33%)
What were the highlights of his more recent work (between 2006-2016)?
- Immunology (49.40%)
- Molecular biology (34.34%)
- Cell biology (31.33%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Immunology, Molecular biology, Cell biology, Transcription factor and Interleukin 21.
His Immunology research incorporates elements of Fibrosis and Type 1 diabetes.
His work deals with themes such as Protein tyrosine phosphatase, SOCS3, Protein inhibitor of activated STAT, Zinc finger and Transcription, which intersect with Molecular biology.
His study in Cell biology is interdisciplinary in nature, drawing from both Cellular differentiation, Cell division and Cell growth.
His Transcription factor research incorporates themes from Psychological repression, Regulation of gene expression and Methylation.
His studies examine the connections between Cytokine and genetics, as well as such issues in Receptor, with regards to Cell fate determination.
Between 2006 and 2016, his most popular works were:
- PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. (243 citations)
- Development and characterization of IL-21–producing CD4+ T cells (206 citations)
- Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice (133 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cytokine
His primary areas of study are Immunology, Molecular biology, Interleukin 21, Cytokine and Cytotoxic T cell.
His work focuses on many connections between Molecular biology and other disciplines, such as Transcription factor, that overlap with his field of interest in Protein subunit, Derepression, Gene expression and Psychological repression.
His studies deal with areas such as Interleukin-21 receptor and Nod, Insulitis as well as Interleukin 21.
His Cytokine study integrates concerns from other disciplines, such as Receptor, Type 1 diabetes, NOD mice and Insulin.
Cytotoxic T cell is closely attributed to Cell biology in his study.
His work carried out in the field of Immune system brings together such families of science as STAT4 and STAT1.
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