Matthias von Herrath

Overview

Best Publications

• CD4 + T cells are required for secondary expansion and memory in CD8 + T lymphocytes

  Edith M. Janssen;Edward E. Lemmens;Tom Wolfe;Urs Christen

  2099
  Citations

• Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

  Tom L. Van Belle;Ken T. Coppieters;Matthias G. Von Herrath

  1396
  Citations

• Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease

  Robert S. Fujinami;Matthias G. von Herrath;Urs Christen;J. Lindsay Whitton

  837
  Citations

• Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

  Ken T. Coppieters;Francesco Dotta;Natalie Amirian;Peter D. Campbell

  752
  Citations

• Resolution of a chronic viral infection after interleukin-10 receptor blockade

  Mette Ejrnaes;Christophe M. Filippi;Marianne M. Martinic;Eleanor M. Ling

  700
  Citations

• Antigen-driven effector CD8 T cell function regulated by T-bet.

  Brandon M. Sullivan;Amy Juedes;Susanne J. Szabo;Matthias von Herrath

  609
  Citations

• How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

  Matthias G. von Herrath;Janel Dockter;Michael B.A. Oldstone

  438
  Citations

• Antigen-induced regulatory T cells in autoimmunity

  Matthias G. von Herrath;Leonard C. Harrison

  420
  Citations

• Viral Trigger for Type 1 Diabetes: Pros and Cons

  Christophe M. Filippi;Matthias G. von Herrath

  368
  Citations

• Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

  Damien Bresson;Lisa Togher;Evelyn Rodrigo;Yali Chen

  360
  Citations

• Type 1 diabetes as a relapsing-remitting disease?

  Matthias von Herrath;Srinath Sanda;Kevan Herold

  326
  Citations

• Microorganisms and autoimmunity: making the barren field fertile?

  Matthias G von Herrath;Robert S Fujinami;J Lindsay Whitton

  325
  Citations

• Interferon-γ Is Essential for Destruction of β Cells and Development of Insulin-dependent Diabetes Mellitus

  Matthias G. von Herrath;Michael B.A. Oldstone

  314
  Citations

• Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

  Sarah J. Richardson;Teresa Rodriguez-Calvo;Ivan C. Gerling;Clayton E. Mathews

  313
  Citations

• Rho Family Proteins Modulate Rapid Apoptosis Induced by Cytotoxic T Lymphocytes and Fas

  M. Cecilia Subauste;Matthias Von Herrath;Valerie Benard;Chester E. Chamberlain

  302
  Citations

• Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes

  Bart O Roep;Mark Atkinson;Matthias von Herrath

  297
  Citations

• Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions

  Catherine B. Renard;Farah Kramer;Fredrik Johansson;Najib Lamharzi

  285
  Citations

• How Does Type 1 Diabetes Develop?: The Notion of Homicide or β-Cell Suicide Revisited

  Mark A. Atkinson;Jeffrey A. Bluestone;George S. Eisenbarth;Matthias Hebrok

  280
  Citations

• Among CXCR3 Chemokines, IFN-γ-Inducible Protein of 10 kDa (CXC Chemokine Ligand (CXCL) 10) but Not Monokine Induced by IFN-γ (CXCL9) Imprints a Pattern for the Subsequent Development of Autoimmune Disease

  Urs Christen;Dorian B. McGavern;Andrew D. Luster;Matthias G. von Herrath

  261
  Citations

• Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.

  Maya F. Kotturi;Iain Scott;Tom Wolfe;Bjoern Peters

  251
  Citations

• CD8αα-Mediated Survival and Differentiation of CD8 Memory T Cell Precursors

  Loui T. Madakamutil;Urs Christen;Christopher J. Lena;Yiran Wang-Zhu

  246
  Citations

• Evidence for an Underlying CD4 Helper and CD8 T-Cell Defect in B-Cell-Deficient Mice: Failure To Clear Persistent Virus Infection after Adoptive Immunotherapy with Virus-Specific Memory Cells from μMT/μMT Mice

  Dirk Homann;Antoinette Tishon;Dietmar P. Berger;William O. Weigle

  238
  Citations

• Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes

  Teresa Rodriguez-Calvo;Olov Ekwall;Olov Ekwall;Natalie Amirian;Jose Zapardiel-Gonzalo

  221
  Citations

• Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes

  Bart O. Roep;Nanette Solvason;Peter A. Gottlieb;Joana R. F. Abreu

  205
  Citations

• A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis.

  Urs Christen;Tom Wolfe;Ursula Möhrle;Anna C. Hughes

  202
  Citations