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Immunology

D-Index
88
Citations
27409
World Ranking
1169
National Ranking
619

Overview

Michael Croft is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with substantial work in Immunology, Physiology, Pulmonary and Respiratory Medicine, Dermatology, and Surgery.

The main topics covered in their research include:

  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Asthma and respiratory diseases
  • T-cell and B-cell Immunology
  • Eosinophilic Esophagitis
  • Dermatology and Skin Diseases
  • Immunotherapy and Immune Responses

Michael Croft has contributed to multiple peer-reviewed papers. Notable recent publications include:

  • "OX40 in the Pathogenesis of Atopic Dermatitis-A New Therapeutic Target" (2024) published in the American Journal of Clinical Dermatology
  • "Realigning the LIGHT signaling network to control dysregulated inflammation" (2022) published in The Journal of Experimental Medicine
  • "Clearance of apoptotic cells by lung alveolar macrophages prevents development of house dust mite-induced asthmatic lung inflammation" (2020) published in the Journal of Allergy and Clinical Immunology
  • "Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype" (2020) published in Gastroenterology
  • "TL1A Promotes Lung Tissue Fibrosis and Airway Remodeling" (2020) published in The Journal of Immunology

The most frequent coauthors collaborating with Michael Croft include Haruka Miki, Rinkesh Kumar Gupta, Gurupreet S. Sethi, Mario C. Manresa, and Rana Herro.

The scientist regularly publishes in several academic journals. The most common publication venues are:

  • The Journal of Immunology
  • Journal of Allergy and Clinical Immunology
  • Allergy
  • American Journal of Clinical Dermatology
  • Gastroenterology

Best Publications

  • Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

    Michael Croft

  • The role of TNF superfamily members in T-cell function and diseases

    Michael Croft

  • Ox-40 Ligand: A Potent Costimulatory Molecule for Sustaining Primary CD4 T Cell Responses

    Irene Gramaglia;Andrew D. Weinberg;Michael Lemon;Michael Croft

  • Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

    M Croft;L M Bradley;S L Swain

  • Control of Immunity by the TNFR-Related Molecule OX40 (CD134)

    Michael Croft

  • The Significance of OX40 and OX40L to T cell Biology and Immune Disease

    Michael Croft;Takanori So;Wei Duan;Pejman Soroosh

  • Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.

    Michael Croft;Laura Carter;Susan L. Swain;Richard W. Dutton

  • OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells.

    Paul R Rogers;Jianxun Song;Irene Gramaglia;Nigel Killeen

  • The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.

    Irene Gramaglia;Amha Jember;Susanne D. Pippig;Andrew D. Weinberg

  • Clinical targeting of the TNF and TNFR superfamilies

    Michael Croft;Chris A. Benedict;Carl F. Ware

  • Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development.

    Susan L. Swain;Linda M. Bradley;Michael Croft;Susan Tonkonogy

  • Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production.

    Taylor A. Doherty;Naseem Khorram;Sean Lund;Amit Kumar Mehta

  • TNF activity and T cells.

    Amit K. Mehta;Donald T. Gracias;Michael Croft

  • A direct role for IFN-gamma in regulation of Th1 cell development.

    L M Bradley;D K Dalton;M Croft

  • Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.

    C Dubey;M Croft;S L Swain

  • Lung-resident tissue macrophages generate Foxp3 + regulatory T cells and promote airway tolerance

    Pejman Soroosh;Taylor A. Doherty;Wei Duan;Amit Kumar Mehta

  • Costimulation of T cells by OX40, 4-1BB, and CD27

    Michael Croft

  • Signaling through OX40 (CD134) breaks peripheral T-cell tolerance

    Pratima Bansal-Pakala;Amha Gebre-Hiwot Jember;Michael Croft

  • Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements.

    M Croft;D D Duncan;S L Swain

  • Accessory Molecule and Costimulation Requirements for CD4 T Cell Response.

    Michael Croft;Caroline Dubey

Frequent Co-Authors

Carl F. Ware
Carl F. Ware Sanford Burnham Prebys Medical Discovery Institute
David H. Broide
David H. Broide University of California, San Diego
Susan L. Swain
Susan L. Swain University of Massachusetts Chan Medical School
Byoung S. Kwon
Byoung S. Kwon Tulane University
Matthias von Herrath
Matthias von Herrath Diabetes Research Institute Foundation
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Robert S. Mittler
Robert S. Mittler Emory University
Megan Sykes
Megan Sykes Columbia University
Shane Crotty
Shane Crotty La Jolla Institute For Allergy & Immunology
Chris A. Benedict
Chris A. Benedict La Jolla Institute For Allergy & Immunology

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