T cell, Cell biology, Immunology, Cytotoxic T cell and Antigen-presenting cell are his primary areas of study. His work in T cell tackles topics such as Apoptosis which are related to areas like Intracellular. His study in Cell biology is interdisciplinary in nature, drawing from both Receptor, Cytokine and T-cell receptor.
His study connects CD40 and Immunology. His Cytotoxic T cell research is multidisciplinary, incorporating perspectives in Priming and CD8. As a part of the same scientific family, he mostly works in the field of Antigen-presenting cell, focusing on Molecular biology and, on occasion, Dendritic cell, Leukotriene E4, Leukotriene D4 and Leukotriene.
The scientist’s investigation covers issues in Immunology, Cell biology, T cell, Cytotoxic T cell and Immune system. His Immunology study frequently draws connections to adjacent fields such as CD40. His Cell biology study incorporates themes from CD28, Receptor and T-cell receptor.
In general T cell study, his work on CD134 and Naive T cell often relates to the realm of Cellular differentiation and Population, thereby connecting several areas of interest. The various areas that Michael Croft examines in his Cytotoxic T cell study include CD8 and Virology. His Antigen-presenting cell research is multidisciplinary, incorporating elements of Molecular biology, Interleukin 12, Priming and Antigen presentation.
His primary areas of study are Cancer research, Immunology, Inflammation, Tumor necrosis factor alpha and Receptor. His study in Allergen, T cell, Hepatitis B, Innate immune system and Hepatitis B virus is carried out as part of his studies in Immunology. His research links CD40 with T cell.
His work deals with themes such as Bronchoalveolar lavage, Signal transduction, Cytokine and Hepatocyte, which intersect with Inflammation. His Receptor research is multidisciplinary, relying on both Intramolecular force and Cell biology. Michael Croft combines subjects such as Transfection and Conditional gene knockout with his study of Cell biology.
Michael Croft mostly deals with Tumor necrosis factor alpha, Immunology, Cancer research, Cytotoxic T cell and Receptor. His work deals with themes such as Liver injury and CD40, which intersect with Immunology. His Cancer research study combines topics in areas such as Cancer, Cytokine, Lymphotoxin, Monoclonal and Inflammation.
Michael Croft interconnects Humanized mouse, Tumor necrosis factor receptor 2, Antibody and Cancer immunotherapy in the investigation of issues within Cytotoxic T cell. His Receptor study combines topics from a wide range of disciplines, such as Protein structure, CD137, Binding site and Protein–protein interaction. His specific area of interest is T cell, where Michael Croft studies IL-2 receptor.
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Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?
Nature Reviews Immunology (2003)
The role of TNF superfamily members in T-cell function and diseases
Nature Reviews Immunology (2009)
Ox-40 Ligand: A Potent Costimulatory Molecule for Sustaining Primary CD4 T Cell Responses
Irene Gramaglia;Andrew D. Weinberg;Michael Lemon;Michael Croft.
Journal of Immunology (1998)
Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.
M Croft;L M Bradley;S L Swain.
Journal of Immunology (1994)
Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.
Michael Croft;Laura Carter;Susan L. Swain;Richard W. Dutton.
Journal of Experimental Medicine (1994)
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells.
Paul R Rogers;Jianxun Song;Irene Gramaglia;Nigel Killeen.
Control of Immunity by the TNFR-Related Molecule OX40 (CD134)
Annual Review of Immunology (2010)
The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.
Irene Gramaglia;Amha Jember;Susanne D. Pippig;Andrew D. Weinberg.
Journal of Immunology (2000)
The Significance of OX40 and OX40L to T cell Biology and Immune Disease
Michael Croft;Takanori So;Wei Duan;Pejman Soroosh.
Immunological Reviews (2009)
Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development.
Susan L. Swain;Linda M. Bradley;Michael Croft;Susan Tonkonogy.
Immunological Reviews (1991)
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