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Microbiology

D-Index
49
Citations
8840
World Ranking
4568
National Ranking
1766

Overview

Chris A. Benedict is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research spans multiple scientific disciplines, with notable contributions in medicine, immunology and microbiology, and agricultural and biological sciences.

The primary fields of study include:

  • Medicine
  • Immunology and Microbiology
  • Agricultural and Biological Sciences

Subfields within these areas reflect a focus on immunology, epidemiology, plant science, molecular biology, and physiology, indicating a broad and interdisciplinary approach to their research topics.

  • Immunology
  • Epidemiology
  • Plant Science
  • Molecular Biology
  • Physiology

Themes explored in Chris A. Benedict's work include cytomegalovirus and herpesvirus research, herpesvirus infections and treatments, immune cell function and interaction, berry genetics and cultivation research, T-cell and B-cell immunology, plant disease management techniques, and RNA regulation and disease.

  • Cytomegalovirus and herpesvirus research
  • Herpesvirus Infections and Treatments
  • Immune Cell Function and Interaction
  • Berry genetics and cultivation research
  • T-cell and B-cell Immunology
  • Plant Disease Management Techniques
  • RNA regulation and disease

The scientist has frequently published in various academic venues, reflecting the multifaceted nature of their research interests. These publication venues include:

  • The Journal of Immunology
  • HortScience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Circulation

Frequently collaborating co-authors are:

  • Simon Brunel
  • Alessandro Sette
  • Klaus Ley
  • Gaëlle Picarda
  • Lisa W. DeVetter

Recent notable publications by Chris A. Benedict include:

  • Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B 100 -Reactive CD4 + T-Regulatory Cells, 2020, Circulation
  • Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response, 2020, Science Advances
  • Profiling Human Cytomegalovirus-Specific T Cell Responses Reveals Novel Immunogenic Open Reading Frames, 2021, Journal of Virology
  • Plastic Mulches Improved Plant Growth and Suppressed Weeds in Late Summer-planted Floricane-fruiting Raspberry, 2020, HortScience
  • Evaluation of Pre-harvest Microbiological Safety of Blueberry Production With or Without Manure-Derived Fertilizer, 2020, Frontiers in Microbiology

Best Publications

  • To kill or be killed: viral evasion of apoptosis

    Chris A. Benedict;Paula S. Norris;Carl F. Ware

  • Clinical targeting of the TNF and TNFR superfamilies

    Michael Croft;Chris A. Benedict;Carl F. Ware

  • A fourth IκB protein within the NF-κB signaling module

    Soumen Basak;Hana Kim;Jeffrey D. Kearns;Vinay Tergaonkar

  • DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB

    Manuele Rebsamen;Leonhard X Heinz;Etienne Meylan;Marie‐Cécile Michallet

  • The Lymphotoxin-β Receptor Is Necessary and Sufficient for LIGHT-mediated Apoptosis of Tumor Cells

    Isabelle A. Rooney;Kris D. Butrovich;Alison A. Glass;Stephen Borboroglu

  • Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway.

    Timothy C. Cheung;Ian R. Humphreys;Karen G. Potter;Paula S. Norris

  • Cutting edge: the mechanism of invariant NKT cell responses to viral danger signals.

    Aaron J. Tyznik;Emmanuel Tupin;Niranjana A. Nagarajan;Min J. Her

  • Cutting Edge: A Novel Viral TNF Receptor Superfamily Member in Virulent Strains of Human Cytomegalovirus

    Chris A. Benedict;Kris D. Butrovich;Nell S. Lurain;Jacques Corbeil

  • Three Adenovirus E3 Proteins Cooperate to Evade Apoptosis by Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptor-1 and -2

    Chris A. Benedict;Paula S. Norris;Theodore I. Prigozy;Jean-Luc Bodmer

  • Human cytomegalovirus UL144 open reading frame: sequence hypervariability in low-passage clinical isolates

    Nell S. Lurain;Kathi S. Kapell;Diana D. Huang;Jeffery A. Short

  • Lymphotoxin-mediated crosstalk between B cells and splenic stroma promotes the initial type I interferon response to cytomegalovirus

    Kirsten Schneider;Andrea Loewendorf;Carl De Trez;James Fulton

  • The αβ T Cell Response to Self-Glycolipids Shows a Novel Mechanism of CD1b Loading and a Requirement for Complex Oligosaccharides

    Abdijapar Shamshiev;Alena Donda;Theodore I Prigozy;Lucia Mori

  • Cytomegalovirus exploits IL-10-mediated immune regulation in the salivary glands

    Ian R. Humphreys;Carl de Trez;April Kinkade;Chris A. Benedict

  • A noncanonical function of cGAMP in inflammasome priming and activation.

    Karen V. Swanson;Robert D. Junkins;Cathryn J. Kurkjian;Elizabeth Holley-Guthrie

  • Cytomegalovirus: Shape-Shifting the Immune System.

    Gaëlle Picarda;Chris A. Benedict

  • Determination of the binding affinity of an anti-CD34 single-chain antibody using a novel, flow cytometry based assay

    Chris A Benedict;Albert J MacKrell;W.French Anderson

  • Death and survival: viral regulation of TNF signaling pathways.

    Chris A Benedict;Theresa A Banks;Carl F Ware

  • Specific Remodeling of Splenic Architecture by Cytomegalovirus

    Chris A Benedict;Carl De Trez;Kirsten Schneider;Sukwon Ha

  • Cutting Edge: Murine Cytomegalovirus Induces a Polyfunctional CD4 T Cell Response

    Ramon Arens;Peng Wang;John Sidney;Andrea Loewendorf

  • Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100–Reactive CD4+ T-Regulatory Cells

    Dennis Wolf;Dennis Wolf;Teresa Gerhardt;Teresa Gerhardt;Holger Winkels;Nathaly Anto Michel;Nathaly Anto Michel

  • The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Vα14i NKT cells

    Dirk Elewaut;Anna P. Lawton;Niranjana A. Nagarajan;Niranjana A. Nagarajan;Emanual Michael Maverakis

  • Lymphotoxins and Cytomegalovirus Cooperatively Induce Interferon-β, Establishing Host-Virus Détente

    Chris A Benedict;Theresa A Banks;Lionel Senderowicz;Mira Ko

  • Dendritic Cell Programming by Cytomegalovirus Stunts Naive T Cell Responses via the PD-L1/PD-1 Pathway

    Chris A. Benedict;Andrea Loewendorf;Zacarias Garcia;Bruce R. Blazar

Frequent Co-Authors

Carl F. Ware
Carl F. Ware Sanford Burnham Prebys Medical Discovery Institute
Ramon Arens
Ramon Arens Leiden University Medical Center
Michael Croft
Michael Croft La Jolla Institute For Allergy & Immunology
Mitchell Kronenberg
Mitchell Kronenberg University of California, San Diego
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Peter Ghazal
Peter Ghazal Cardiff University
Pascal Schneider
Pascal Schneider University of Lausanne
Klaus Pfeffer
Klaus Pfeffer Heinrich Heine University Düsseldorf
Stephen M. Hedrick
Stephen M. Hedrick University of California, San Diego

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