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Immunology

D-Index
56
Citations
11851
World Ranking
3716
National Ranking
88

Overview

Gennaro De Libero is affiliated with the University Hospital of Basel in Switzerland and conducts research primarily in the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their work focuses extensively on Immunology, with specific attention to molecular biology, oncology, physiology, and infectious diseases subfields.

The scientist's research covers a range of topics including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Adenosine and Purinergic Signaling
  • Tuberculosis Research and Epidemiology
  • RNA modifications and cancer
  • HIV Research and Treatment

Among their recent scientific publications are:

  • "Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells" (2024), published in Science Immunology
  • "The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells" (2024), published in Immunity
  • "Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses" (2023), published in The Journal of Experimental Medicine
  • "Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection" (2022), published in Nature Microbiology
  • "MR1-Restricted T Cells Are Unprecedented Cancer Fighters" (2020), published in Frontiers in Immunology

The frequent publication venues for this scientist include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Nature Microbiology
  • Immunity
  • Science Immunology

Collaborations are an important aspect of their work, with frequent coauthors being:

  • Lucia Mori
  • Andrew Chancellor
  • Alessandro Vacchini
  • Vladimir Nosi
  • Julian Spagnuolo

Gennaro De Libero's research contributions highlight their involvement in advancing understanding of T-cell immunology and adaptive immune responses with a focus on MR1-restricted T cells. Their work also intersects with infectious disease research, particularly tuberculosis, as well as cancer immunology and molecular mechanisms underlying immune system regulation.

Best Publications

  • Human T Cell Receptor γδ Cells Recognize Endogenous Mevalonate Metabolites in Tumor Cells

    Hans-Jürgen Gober;Magdalena Kistowska;Lena Angman;Paul Jenö

  • Metformin as adjunct antituberculosis therapy

    Amit Singhal;Liu Jie;Pavanish Kumar;Gan Suay Hong

  • Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells.

    Stefano Vavassori;Anil Kumar;Gan S Wan;Gundimeda S Ramanjaneyulu

  • Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis.

    Martine Gilleron;Steffen Stenger;Zaima Mazorra;Frederick Wittke

  • IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells

    Xin-Zi Tang;Juandy Jo;Anthony T. Tan;Elena Sandalova

  • Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

    Marco Lepore;Artem Kalinicenko;Alessia Colone;Bhairav Paleja

  • Self glycolipids as T-cell autoantigens.

    Abdijapar Shamshiev;Alena Donda;Ilaria Carena;Lucia Mori

  • Human CD1-restricted T cell recognition of lipids from pollens

    Elisabetta Agea;Anna Russano;Onelia Bistoni;Roberta Mannucci

  • Assistance of Microbial Glycolipid Antigen Processing by CD1e

    Sabrina Mariotti;Catherine Angenieux;Martine Gilleron

  • Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells.

    G De Libero;G Casorati;C Giachino;C Carbonara

  • Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver.

    Juandy Jo;Anthony T. Tan;James E. Ussher;Elena Sandalova

  • Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias.

    Pegah Nowbakht;Pegah Nowbakht;Mihai-Constantin S. Ionescu;Mihai-Constantin S. Ionescu;Andreas Rohner;Andreas Rohner;Christian P. Kalberer;Christian P. Kalberer

  • Mycobacteria-reactive Lyt-2+ T cell lines

    Gennaro De Libero;Inge Flesch;Stefan H. E. Kaufmann

  • Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus

    Federica Facciotti;Federica Facciotti;Gundimeda S Ramanjaneyulu;Marco Lepore;Sebastiano Sansano

  • Human Vγ9-Vδ2 cells are stimulated in a crossreactive fashion by a variety of phosphorylated metabolites

    Martin R. Bürk;Lucia Mori;Gennaro de Libero

  • Recognition of lipid antigens by T cells

    Gennaro De Libero;Lucia Mori

  • Sentinel function of broadly reactive human γδ T cells

    Gennaro De Libero

  • The αβ T Cell Response to Self-Glycolipids Shows a Novel Mechanism of CD1b Loading and a Requirement for Complex Oligosaccharides

    Abdijapar Shamshiev;Alena Donda;Theodore I Prigozy;Lucia Mori

  • Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells.

    Emilie Layre;Emilie Layre;Anthony Collmann;Max Bastian;Sabrina Mariotti

  • Functionally diverse human T cells recognize non-microbial antigens presented by MR1

    Marco Lepore;Artem Kalinichenko;Salvatore Calogero;Pavanish Kumar

  • Corrigendum: Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

    Marco Lepore;Artem Kalinichenko;Alessia Colone;Bhairav Paleja

Frequent Co-Authors

Lucia Mori
Lucia Mori University of Basel
Germain Puzo
Germain Puzo Federal University of Toulouse Midi-Pyrénées
Martine Gilleron
Martine Gilleron Federal University of Toulouse Midi-Pyrénées
Michael Poidinger
Michael Poidinger Murdoch Children's Research Institute
Luigi Terracciano
Luigi Terracciano University Hospital of Basel
Paolo Dellabona
Paolo Dellabona Vita-Salute San Raffaele University
Giulia Casorati
Giulia Casorati Vita-Salute San Raffaele University
Steven A. Porcelli
Steven A. Porcelli Albert Einstein College of Medicine
Lionel Mourey
Lionel Mourey Federal University of Toulouse Midi-Pyrénées

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