Ruth S. Slack

Research.com Recognitions

• 2017 - Fellow of the Royal Society of Canada Academy of Science

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy

  Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  8665
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  895
  Citations

• Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

  Mireille Khacho;Alysen Clark;Devon S. Svoboda;Joelle Azzi

  692
  Citations

• Role of AIF in caspase-dependent and caspase-independent cell death

  Sean P Cregan;Valina L Dawson;Ruth S Slack

  686
  Citations

• Caspase 3 activity is required for skeletal muscle differentiation

  Pasan Fernando;John F. Kelly;Kim Balazsi;Ruth S. Slack

  672
  Citations

• Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

  Sean P. Cregan;Andre Fortin;Jason G. MacLaurin;Steven M. Callaghan

  597
  Citations

• Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons.

  Consiglia Pacelli;Nicolas Giguère;Marie Josée Bourque;Martin Lévesque

  534
  Citations

• Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons

  Sean P. Cregan;Jason G. MacLaurin;Constance G. Craig;George S. Robertson

  476
  Citations

• Loss of the Parkinson’s Disease-linked gene DJ-1 perturbs mitochondrial dynamics

  I. Irrcher;H. Aleyasin;E.L. Seifert;S.J. Hewitt

  441
  Citations

• OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

  David A Patten;Jacob Wong;Mireille Khacho;Vincent Soubannier

  382
  Citations

• Cyclin-dependent kinases as a therapeutic target for stroke

  Hitoshi Osuga;Sachiko Osuga;Fuhu Wang;Raouf Fetni

  372
  Citations

• Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

  Patrice D. Smith;Stephen J. Crocker;Vernice Jackson-Lewis;Kelly L. Jordan-Sciutto

  359
  Citations

• Involvement of Interferon-γ in Microglial-Mediated Loss of Dopaminergic Neurons

  Matthew P Mount;Arman Lira;David Grimes;Patrice D Smith

  357
  Citations

• Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.

  Stephen J. Crocker;Patrice D. Smith;Vernice Jackson-Lewis;Wiplore R. Lamba

  338
  Citations

• Reactive Oxygen Species: Stuck in the Middle of Neurodegeneration

  David A Patten;Marc Germain;Melissa A Kelly;Ruth S Slack

  324
  Citations

• Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma.

  Danian Chen;Izhar Livne-bar;Jackie L Vanderluit;Ruth S Slack

  321
  Citations

• Mitochondria as central regulators of neural stem cell fate and cognitive function

  Mireille Khacho;Richard Harris;Ruth S Slack

  317
  Citations

• Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP

  M. Emdadul Haque;Kelly J. Thomas;Cheryl D'Souza;Steve Callaghan

  301
  Citations

• Involvement of Cell Cycle Elements, Cyclin-dependent Kinases, pRb, and E2F·DP, in B-amyloid-induced Neuronal Death

  Andrew Giovanni;Friederike Wirtz-Brugger;Elizabeth Keramaris;Ruth Slack

  299
  Citations