David S. Park

Overview

Best Publications

• Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

  Ruben K. Dagda;Salvatore J. Cherra;Scott M. Kulich;Scott M. Kulich;Anurag Tandon

  1063
  Citations

• Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress

  Raymond H. Kim;Patrice D. Smith;Hossein Aleyasin;Shawn Hayley

  860
  Citations

• Caveolin-1-deficient Mice Are Lean, Resistant to Diet-induced Obesity, and Show Hypertriglyceridemia with Adipocyte Abnormalities

  Babak Razani;Terry P. Combs;Xiao Bo Wang;Philippe G. Frank

  710
  Citations

• Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

  Andrew W Greene;Karl Grenier;Miguel A Aguileta;Stephanie Muise

  702
  Citations

• Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

  Mireille Khacho;Alysen Clark;Devon S. Svoboda;Joelle Azzi

  692
  Citations

• Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

  Sean P. Cregan;Andre Fortin;Jason G. MacLaurin;Steven M. Callaghan

  597
  Citations

• Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons

  Sean P. Cregan;Jason G. MacLaurin;Constance G. Craig;George S. Robertson

  476
  Citations

• Caveolin, Caveolae, and Endothelial Cell Function

  Philippe G. Frank;Scott E. Woodman;David S. Park;Michael P. Lisanti

  471
  Citations

• β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease

  Shuchi Mittal;Kjetil Bjørnevik;Kjetil Bjørnevik;Doo Soon Im;Adrian Flierl

  456
  Citations

• Constitutive Nuclear Factor-κB Activity Is Required for Central Neuron Survival

  Asha L. Bhakar;Laura-Lee Tannis;Christine Zeindler;Maria Pia Russo

  444
  Citations

• Loss of the Parkinson’s Disease-linked gene DJ-1 perturbs mitochondrial dynamics

  I. Irrcher;H. Aleyasin;E.L. Seifert;S.J. Hewitt

  441
  Citations

• The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin.

  Ehud Chorin;Matthew Dai;Eric Shulman;Lalit Wadhwani

  426
  Citations

• Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

  Zohreh Galehdar;Patrick Swan;Benjamin Fuerth;Steven M. Callaghan

  418
  Citations

• Caveolae-deficient endothelial cells show defects in the uptake and transport of albumin in vivo.

  William Schubert;Philippe G. Frank;Babak Razani;David S. Park

  398
  Citations

• G1/S Cell Cycle Blockers and Inhibitors of Cyclin-Dependent Kinases Suppress Camptothecin-Induced Neuronal Apoptosis

  David S. Park;Erick J. Morris;Lloyd A. Greene;Herbert M. Geller

  394
  Citations

• Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

  David S. Park;Beth Levine;Giovanna Ferrari;Lloyd A. Greene

  390
  Citations

• Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy

  Maria Xilouri;Tereza Vogiatzi;Kostas Vekrellis;David Park

  387
  Citations

• Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons.

  David S. Park;Stephen E. Farinelli;Lloyd A. Greene

  385
  Citations

• OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

  David A Patten;Jacob Wong;Mireille Khacho;Vincent Soubannier

  382
  Citations

• Cyclin-dependent Kinases Participate in Death of Neurons Evoked by DNA-damaging Agents

  David S. Park;Erick J. Morris;Jaya Padmanabhan;Michael L. Shelanski

  381
  Citations