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Diane C. Lagace

Diane C. Lagace

D-Index & Metrics

Neuroscience

D-Index
41
Citations
19790
World Ranking
7738
National Ranking
456

Overview

Diane C. Lagace is affiliated with the University of Ottawa in Canada. Their research spans multiple areas within neuroscience and molecular biology, with significant contributions to understanding brain development, neurogenesis, and neuroplasticity mechanisms.

The main fields of study for Diane C. Lagace include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these areas, their work focuses on several subfields:

  • Molecular Biology
  • Neurology
  • Developmental Neuroscience
  • Cellular and Molecular Neuroscience
  • Surgery

The topics frequently addressed in Diane C. Lagace's research reflect a broad engagement with brain function and pathology:

  • Neurogenesis and neuroplasticity mechanisms
  • Epigenetics and DNA Methylation
  • Neonatal and fetal brain pathology
  • Neuroscience and Neuropharmacology Research
  • Transcranial Magnetic Stimulation Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neonatal Respiratory Health Research

Selected recent publications demonstrate the scope and impact of their research:

  • "Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis" (2022), Journal of Clinical Investigation
  • "Metformin promotes CNS remyelination and improves social interaction following focal demyelination through CBP Ser436 phosphorylation" (2020), Experimental Neurology
  • "Single-Cell and Single-Nucleus RNAseq Analysis of Adult Neurogenesis" (2022), Cells
  • "The Emergence of Stereotyped Kinematic Synergies when Mice Reach to Grasp Following Stroke" (2021), Neurorehabilitation and Neural Repair
  • "Developmental and Interventional Plasticity of Motor Maps after Perinatal Stroke" (2021), Journal of Neuroscience

Diane C. Lagace has published articles in a variety of venues, reflecting interdisciplinary collaboration and cross-field relevance:

  • Experimental Neurology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Cells
  • Methods in molecular biology

The scientist collaborates frequently with colleagues including:

  • Alena Kalinina
  • Yingben Xue
  • Ruth S. Slack
  • Baptiste Lacoste
  • Ayden Gouveia

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions

    Vaishnav Krishnan;Ming Hu Han;Danielle L. Graham;Olivier Berton

  • Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

    Mireille Khacho;Alysen Clark;Devon S. Svoboda;Joelle Azzi

  • Dynamic contribution of nestin-expressing stem cells to adult neurogenesis.

    Diane C. Lagace;Mary C. Whitman;Michele A. Noonan;Jessica L. Ables

  • Neurod1 is essential for the survival and maturation of adult-born neurons.

    Zhengliang Gao;Kerstin Ure;Jessica L. Ables;Diane C. Lagace

  • Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance

    Diane C. Lagace;Michael H. Donovan;Nathan A. DeCarolis;Laure A. Farnbauch

  • The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

    David Petrik;Diane C. Lagace;Amelia J. Eisch

  • Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord.

    James Battiste;Amy W. Helms;Euiseok J. Kim;Trisha K. Savage

  • Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.

    Mireille Khacho;Alysen Clark;Devon S. Svoboda;Jason G. MacLaurin

  • Gender and endogenous levels of estradiol do not influence adult hippocampal neurogenesis in mice.

    Diane C. Lagace;Stephanie J. Fischer;Amelia J. Eisch

  • Autophagy supports genomic stability by degrading retrotransposon RNA

    Huishan Guo;Maneka Chitiprolu;David Gagnon;Lingrui Meng

  • Focal cerebral ischemia induces a multilineage cytogenic response from adult subventricular zone that is predominantly gliogenic.

    Lu Li;Kate M. Harms;P. Britten Ventura;Diane C. Lagace

  • Cdk5 is essential for adult hippocampal neurogenesis

    Diane C. Lagace;David R. Benavides;Janice W. Kansy;Marina Mapelli

  • Making a neuron: Cdk5 in embryonic and adult neurogenesis.

    Sebastian Jessberger;Fred H. Gage;Amelia J. Eisch;Diane C. Lagace

  • In vivo contribution of nestin- and GLAST-lineage cells to adult hippocampal neurogenesis

    Nathan A. DeCarolis;Maxwell Mechanic;David Petrik;Adam Carlton

  • Conditional Disruption of Calpain in the CNS Alters Dendrite Morphology, Impairs LTP, and Promotes Neuronal Survival following Injury

    Mandana Amini;Chun Lei Ma;Rasoul Farazifard;Guoqi Zhu

  • Cell-autonomous inactivation of the reelin pathway impairs adult neurogenesis in the hippocampus.

    Catia M. Teixeira;Michelle M. Kron;Nuria Masachs;Helen Zhang

  • Chronic Stress Induces Anxiety via an Amygdalar Intracellular Cascade that Impairs Endocannabinoid Signaling

    Zhaohong Qin;Xun Zhou;Nihar R. Pandey;Haley A. Vecchiarelli

  • Juvenile Administration of Methylphenidate Attenuates Adult Hippocampal Neurogenesis

    Diane C. Lagace;Jessica K. Yee;Carlos A. Bolaños;Amelia J. Eisch

  • Inhibition of Histone Deacetylase Activity by Valproic Acid Blocks Adipogenesis*

    Unknown

  • Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease.

    Maxime W. C. Rousseaux;Paul C. Marcogliese;Dianbo Qu;Sarah J. Hewitt

Frequent Co-Authors

Amelia J. Eisch
Amelia J. Eisch University of Pennsylvania
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Vaishnav Krishnan
Vaishnav Krishnan Baylor College of Medicine
Olivier Berton
Olivier Berton University of Pennsylvania
Changlian Zhu
Changlian Zhu University of Gothenburg
Chitra D. Mandyam
Chitra D. Mandyam Veterans Health Administration
Earl G. Brown
Earl G. Brown University of Ottawa
Michel Baudry
Michel Baudry Western University of Health Sciences
Tak Pan Wong
Tak Pan Wong McGill University

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