World's Best Scientists 2026 revealed!
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Biology and Biochemistry
Greece
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
53388
World Ranking
4428
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Greece Leader Award
  • 2025 - Research.com Biology and Biochemistry in Greece Leader Award
  • 2023 - Research.com Biology and Biochemistry in Greece Leader Award
  • 2022 - Research.com Biology and Biochemistry in Greece Leader Award

Overview

Leonidas Stefanis is affiliated with the National and Kapodistrian University of Athens in Greece. Their research focuses primarily on medicine and neuroscience, with specific attention to neurology, molecular biology, and cellular and molecular neuroscience. Stefanis has contributed extensively to the understanding of neurological disorders and treatments, including Parkinson's disease mechanisms and treatments, genetic neurodegenerative diseases, and dementia and cognitive impairment research.

The scientist has published numerous papers in key venues related to their fields. Frequent publication outlets include Movement Disorders, bioRxiv (Cold Spring Harbor Laboratory), Parkinsonism & Related Disorders, npj Parkinsonʼs Disease, and Neurological Sciences.

Stefanis's recent papers include the following:

  • TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A (2022), published in Nature
  • Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease (2021), published in npj Parkinson s Disease
  • A Novel SNCA A30G Mutation Causes Familial Parkinsonʼs Disease (2021), published in Movement Disorders
  • Validation of differentially expressed brain-enriched microRNAs in the plasma of PD patients (2020), published in Annals of Clinical and Translational Neurology
  • Differentially Expressed Circular RNAs in Peripheral Blood Mononuclear Cells of Patients with Parkinson's Disease (2021), published in Movement Disorders

Stefanis frequently collaborates with other researchers, including:

  • Christos Koros
  • Sokratis G. Papageorgiou
  • Anastasia Bougea
  • Nikolaos Papagiannakis
  • María Stamelou

The main topics covered in Stefanis's work include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Nuclear Receptors and Signaling
  • Multiple Sclerosis Research Studies
  • Autism Spectrum Disorder Research
  • Genetic Neurodegenerative Diseases
  • Dementia and Cognitive Impairment Research

Overall, the research output reflects a strong focus on neurodegenerative diseases and their molecular underpinnings, emphasizing Parkinson's disease and related neurological conditions. The collaboration network and choice of publication venues indicate active participation in both clinical and molecular aspects of neuroscience research.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy

    Ana Maria Cuervo;Leonidas Stefanis;Ross Fredenburg;Peter T. Lansbury

  • α-Synuclein in Parkinson’s Disease

    Leonidas Stefanis

  • Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival.

    Evangelia Emmanouilidou;Katerina Melachroinou;Theodoros Roumeliotis;Spiros D. Garbis

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells

    Tereza Vogiatzi;Maria Xilouri;Kostas Vekrellis;Leonidas Stefanis;Leonidas Stefanis

  • Expression of A53T Mutant But Not Wild-Type α-Synuclein in PC12 Cells Induces Alterations of the Ubiquitin-Dependent Degradation System, Loss of Dopamine Release, and Autophagic Cell Death

    Leonidas Stefanis;Kristin E. Larsen;Hardy J. Rideout;David Sulzer

  • Autophagy and its possible roles in nervous system diseases, damage and repair.

    David C Rubinsztein;Marian DiFiglia;Nathaniel Heintz;Ralph A Nixon

  • α-Synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis

    Kristin E. Larsen;Yvonne Schmitz;Matthew D. Troyer;Eugene Mosharov

  • Pathological roles of α-synuclein in neurological disorders

    Kostas Vekrellis;Maria Xilouri;Evangelia Emmanouilidou;Hardy J Rideout

  • Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy

    Maria Xilouri;Tereza Vogiatzi;Kostas Vekrellis;David Park

  • Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.

    Owen A. Ross;Alexandra I. Soto-Ortolaza;Michael G. Heckman;Jan O. Aasly

  • α-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells

    Xiangmin M. Peng;Roya Tehranian;Paula Dietrich;Leonidas Stefanis

  • Multiple Pathways of Neuronal Death Induced by DNA-Damaging Agents, NGF Deprivation, and Oxidative Stress

    David S. Park;Erick J. Morris;Leonidas Stefanis;Carol M. Troy

  • Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies

    Maria Xilouri;Oeystein Roed Brekk;Leonidas Stefanis;Leonidas Stefanis

  • α-Synuclein and protein degradation systems: a reciprocal relationship.

    Maria Xilouri;Oystein Rod Brekk;Leonidas Stefanis;Leonidas Stefanis

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • APOPTOSIS IN NEURODEGENERATIVE DISORDERS

    Leonidas Stefanis;Robert E. Burke;Lloyd A. Greene

Frequent Co-Authors

Maria Stamelou
Maria Stamelou Hygeia Hospital
Nikolaos Scarmeas
Nikolaos Scarmeas National and Kapodistrian University of Athens
Lloyd A. Greene
Lloyd A. Greene Columbia University
Rejko Krüger
Rejko Krüger University of Luxembourg
Georgios Tsivgoulis
Georgios Tsivgoulis National and Kapodistrian University of Athens
David S. Park
David S. Park New York University
Mary H. Kosmidis
Mary H. Kosmidis Aristotle University of Thessaloniki
Enza Maria Valente
Enza Maria Valente University of Pavia
John P. A. Ioannidis
John P. A. Ioannidis Stanford University
Matthew J. Farrer
Matthew J. Farrer University of Florida

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