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D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
62730
World Ranking
2901
National Ranking
1489

Overview

Zhenyu Yue is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with significant contributions focused on neurology, epidemiology, molecular biology, physiology, and cellular and molecular neuroscience.

The scientist's research topics concentrate on several key areas including autophagy in disease and therapy, Parkinson's disease mechanisms and treatments, neuroinflammation and neurodegeneration mechanisms, Alzheimer's disease research and treatments, nuclear receptors and signaling, epigenetics and DNA methylation, and genetics and neurodevelopmental disorders.

Zhenyu Yue has contributed to numerous publications, with frequent appearances in venues such as bioRxiv (Cold Spring Harbor Laboratory), Autophagy, Nature Communications, Science Advances, and Frontiers in Veterinary Science.

Recent notable papers include the following:

  • Autophagy in major human diseases, 2021, The EMBO Journal
  • Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration, 2020, Nature Communications
  • Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease, 2020, Neuron
  • Gut bacterial profiles in Parkinson's disease: A systematic review, 2022, CNS Neuroscience & Therapeutics
  • The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis, 2020, Autophagy

The scientist's work has involved collaboration with several frequent coauthors, including Xianting Li, Insup Choi, Jiahong Lu, Yuanxi Zhang, and Qian Wang.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.

    Zhenyu Yue;Shengkan Jin;Chingwen Yang;Arnold J. Levine

  • Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

    Masaaki Komatsu;Satoshi Waguri;Masato Koike;Yu shin Sou;Yu shin Sou

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

    Guomei Tang;Kathryn Gudsnuk;Sheng-Han Kuo;Marisa L. Cotrina;Marisa L. Cotrina

  • Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.

    Yun Zhong;Qing Jun Wang;Qing Jun Wang;Xianting Li;Ying Yan

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

    Sarah F. Funderburk;Qing Jun Wang;Zhenyu Yue

  • Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

    Masaaki Komatsu;Qing Jun Wang;Qing Jun Wang;Victor L. Friedrich

  • Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

    Virginia Hernández–Gea;Zahra Ghiassi–Nejad;Raphael Rozenfeld;Ronald Gordon

  • Enhancing Depression Mechanisms in Midbrain Dopamine Neurons Achieves Homeostatic Resilience

    Allyson K. Friedman;Jessica J. Walsh;Barbara Juarez;Stacy M. Ku

  • Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S.

    Xianting Li;Jyoti C. Patel;Jing Wang;Marat V. Avshalumov

  • Autophagy in ischemic stroke.

    Pei Wang;Bo-Zong Shao;Zhiqiang Deng;Shi Chen

  • Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations.

    Zejuan Sheng;Shuo Zhang;Daisy Bustos;Tracy Kleinheinz

  • Induction of autophagy in axonal dystrophy and degeneration.

    Qing Jun Wang;Yaomei Ding;D Stave Kohtz;Noboru Mizushima

  • MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation

    Yong-Xi Song;Zhen-Yu Yue;Zhen-Ning Wang;Ying-Ying Xu

Frequent Co-Authors

Masaaki Komatsu
Masaaki Komatsu Juntendo University
Bin Zhang
Bin Zhang Icahn School of Medicine at Mount Sinai
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Wei-Xing Zong
Wei-Xing Zong Rutgers, The State University of New Jersey
Noboru Mizushima
Noboru Mizushima University of Tokyo
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Sergio Lavandero
Sergio Lavandero University of Chile
Ralph N. Martins
Ralph N. Martins Edith Cowan University
Ana Maria Cuervo
Ana Maria Cuervo Albert Einstein College of Medicine
Xiao Ming Yin
Xiao Ming Yin Indiana University

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