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D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
55571
World Ranking
7598
National Ranking
3454

Overview

Wei-Xing Zong is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these areas, their work focuses on several specialized subfields including Molecular Biology, Cancer Research, Oncology, Immunology, and Biotechnology.

Their scholarly output covers a range of topics, with notable emphasis on Cancer, Hypoxia, and Metabolism; RNA Research and Splicing; RNA Modifications and Cancer; Cancer Research and Treatments; RNA and Protein Synthesis Mechanisms; Immune Cell Function and Interaction; and Ferroptosis and Cancer Prognosis.

Wei-Xing Zong has published extensively in journals such as Blood Cancer Discovery, the Journal of Clinical Investigation, Nature Communications, EBioMedicine, and the Proceedings of the National Academy of Sciences. These venues reflect a consistent engagement with cancer-related biological research and clinical investigations.

Their recent papers illustrate a focus on mechanisms underlying cancer pathology and treatment modalities. These include:

  • Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma (2020) Nature Communications
  • Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin (2021) EBioMedicine
  • The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway (2021) Cellular and Molecular Gastroenterology and Hepatology
  • Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints (2022) Proceedings of the National Academy of Sciences
  • Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy (2021) Journal of Hepatology

Collaboration has been a significant aspect of their work, with frequent coauthors including Junrong Yan, Yongbo Wang, Shenglan Gao, Sara Maimouni, and Xiaoyang Su. These collaborations indicate active partnerships in advancing biomedical research within their main areas of study.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

    Michael C. Wei;Michael C. Wei;Wei-Xing Zong;Emily H.-Y. Cheng;Tullia Lindsten

  • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

    Tullia Lindsten;Andrea J. Ross;Ayala King;Wei Xing Zong

  • Necrotic death as a cell fate

    Wei-Xing Zong;Craig B. Thompson

  • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

    Wei-Xing Zong;Tullia Lindsten;Andrea J. Ross;Grant R. MacGregor

  • Mitochondria and Cancer

    Wei-Xing Zong;Joshua D. Rabinowitz;Eileen White

  • The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis

    Wei-Xing Zong;Leonard C. Edelstein;Cailin Chen;Judy Bash

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Consensus guidelines for the detection of immunogenic cell death

    Oliver Kepp;Laura Senovilla;Ilio Vitale;Erika Vacchelli

  • Alkylating DNA damage stimulates a regulated form of necrotic cell death

    Wei-Xing Zong;Dara Ditsworth;Daniel E. Bauer;Zhao-Qi Wang

  • Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

    Wei-Xing Zong;Chi Li;Georgia Hatzivassiliou;Tullia Lindsten

  • Autophagy mediates degradation of nuclear lamina

    Zhixun Dou;Caiyue Xu;Greg Donahue;Takeshi Shimi

  • Chemotherapeutic Approaches for Targeting Cell Death Pathways

    M. Stacey Ricci;Wei Xing Zong

  • The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase.

    Kui Lei;Anjaruwee S. Nimnual;Wei-Xing Zong;Norman J. Kennedy

  • p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation.

    Gerry Melino;Gerry Melino;Francesca Bernassola;Marco Ranalli;Karen Yee

  • Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

    Nadia Jaber;Zhixun Dou;Juei-Suei Chen;Joseph Catanzaro

  • Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

    Jeffrey C. Rathmell;Tullia Lindsten;Wei-Xing Zong;Ryan M. Cinalli

  • Mechanisms of constitutive NF-κB activation in human prostate cancer cells

    Junghan Suh;Junghan Suh;Faribourz Payvandi;Leonard C. Edelstein;Leonard C. Edelstein;Peter S. Amenta

Frequent Co-Authors

Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Jianhua Zhang
Jianhua Zhang The University of Texas MD Anderson Cancer Center
Zhenyu Yue
Zhenyu Yue Icahn School of Medicine at Mount Sinai
Zheng Dong
Zheng Dong Augusta University
Tullia Lindsten
Tullia Lindsten Memorial Sloan Kettering Cancer Center
Sergio Lavandero
Sergio Lavandero University of Chile
Evelina Gatti
Evelina Gatti Aix-Marseille University
Wen-Xing Ding
Wen-Xing Ding University of Kansas
Xiao Ming Yin
Xiao Ming Yin Indiana University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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