World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
114
Citations
103123
World Ranking
808
National Ranking
508

Medicine

D-Index
113
Citations
102122
World Ranking
4814
National Ranking
2612

Overview

Jianhua Zhang is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Molecular Biology, Cancer Research, Oncology, Pulmonary and Respiratory Medicine, and Immunology.

The scientist's recent published works include:

  • Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade, 2021, Nature Medicine
  • Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics, 2020, Nature Communications
  • Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma, 2020, Nature Medicine
  • Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma, 2021, Nature Medicine
  • Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer, 2021, Journal for ImmunoTherapy of Cancer

The main research topics Jianhua Zhang has contributed to include:

  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Ferroptosis and cancer prognosis
  • Prostate Cancer Treatment and Research
  • Cancer-related molecular mechanisms research
  • Acute Myeloid Leukemia Research
  • Lung Cancer Treatments and Mutations

Frequent co-authors collaborating with Jianhua Zhang are:

  • P. Andrew Futreal
  • Xingzhi Song
  • Latasha Little
  • Ignacio I. Wistuba
  • Curtis Gumbs

Publication output appears often in several scientific venues, including:

  • Cancer Research
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Clinical Cancer Research

Jianhua Zhang's work details numerous studies in cancer biology and therapies, focusing on genomics, immunotherapy, and molecular characteristics related to various cancer types, including leukemia, lung, prostate, gastric, and urothelial cancers. Their research includes high-throughput single-cell genomics and studies on tumor heterogeneity and immune checkpoint blockade therapies.

Best Publications

  • Bioconductor: open software development for computational biology and bioinformatics

    Robert C Gentleman;Vincent J Carey;Douglas M. Bates;B.M. Bolstad

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Eric A. Collisson;Joshua D. Campbell;Angela N. Brooks;Angela N. Brooks;Alice H. Berger

  • Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

    V. Gopalakrishnan;V. Gopalakrishnan;C. N. Spencer;C. N. Spencer;L. Nezi;A. Reuben

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

    Jisun Lee;Samantha Giordano;Jianhua Zhang;Jianhua Zhang

  • Identification of Double Stranded Genomic DNA Spanning all Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer

    Christoph Kahlert;Christoph Kahlert;Sonia A. Melo;Alexei Protopopov;Jiabin Tang

  • Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance

    Whijae Roh;Pei Ling Chen;Alexandre Reuben;Christine N. Spencer

  • Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

    Ferdinandos Skoulidis;Lauren A. Byers;Lixia Diao;Vassiliki A. Papadimitrakopoulou

  • Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

    Avnish Kapoor;Wantong Yao;Haoqiang Ying;Sujun Hua

  • Systematic analysis of telomere length and somatic alterations in 31 cancer types

    Floris P Barthel;Wei Wei;Ming Tang;Emmanuel Martinez-Ledesma

  • A kinase–cyclin pair in the RNA polymerase II holoenzyme

    Sha-Mei Liao;Jianhua Zhang;D. A. Jeffery;A. J. Koleske

  • A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations

    Yiqun Zhang;Patrick Kwok-Shing Ng;Melanie Kucherlapati;Fengju Chen

  • Integration of cellular bioenergetics with mitochondrial quality control and autophagy.

    Bradford G Hill;Gloria A Benavides;Jack R Lancaster;Scott Ballinger

  • High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.

    Alejandro Gutierrez;Alejandro Gutierrez;Takaomi Sanda;Ruta Grebliunaite;Arkaitz Carracedo

  • KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer

    Wenting Liao;Michael J. Overman;Adam T. Boutin;Xiaoying Shang

  • Assessing bioenergetic function in response to oxidative stress by metabolic profiling

    Brian P. Dranka;Gloria A. Benavides;Anne R. Diers;Samantha Giordano

Frequent Co-Authors

Victor M. Darley-Usmar
Victor M. Darley-Usmar University of Alabama at Birmingham
John V. Heymach
John V. Heymach The University of Texas MD Anderson Cancer Center
Ignacio I. Wistuba
Ignacio I. Wistuba The University of Texas MD Anderson Cancer Center
Ming Xu
Ming Xu University of Chicago
Guillermo Garcia-Manero
Guillermo Garcia-Manero The University of Texas MD Anderson Cancer Center
Hagop M. Kantarjian
Hagop M. Kantarjian The University of Texas MD Anderson Cancer Center
Carmen Behrens
Carmen Behrens The University of Texas MD Anderson Cancer Center
Stephen G. Swisher
Stephen G. Swisher The University of Texas MD Anderson Cancer Center
Carlos E. Bueso-Ramos
Carlos E. Bueso-Ramos The University of Texas MD Anderson Cancer Center
Alexei Protopopov
Alexei Protopopov The University of Texas MD Anderson Cancer Center

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