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Genetics

D-Index
79
Citations
101957
World Ranking
1599
National Ranking
738

Overview

Alexei Protopopov is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their primary research contributions are situated within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Oncology, Cancer Research, Immunology, and Pulmonary and Respiratory Medicine.

The researcher has contributed extensively to topics such as Cancer Genomics and Diagnostics, Single-cell and Spatial Transcriptomics, Cancer Immunotherapy and Biomarkers, Immune Cells in Cancer, Molecular Biology Techniques and Applications, Cancer Research and Treatments, and Genomics and Chromatin Dynamics.

Notable publications authored or co-authored by the scientist include:

  • Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade, 2020, OncoImmunology
  • A functional genomic approach to actionable gene fusions for precision oncology, 2022, Science Advances
  • Abstract 4451: Combination of local mRNA immunotherapy with systemic immune checkpoint blockade demonstrates anti-tumor activity across a diverse range of preclinical syngeneic tumor models, 2020, Cancer Research
  • 277MO SAR439859, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/ HER2- metastatic breast cancer (mBC): Biomarker analyses from a phase I/II study, 2020, Annals of Oncology
  • Abstract 4276: Target enrichment to enable RNA-sequencing on FFPE samples: Application to a patient selection biomarkers in colorectal cancer, 2020, Cancer Research

Frequent collaborators include:

  • Jack Pollard
  • Joachim Theilhaber
  • Natalia V. Malkova
  • Emma Wang
  • Joon Sang Lee

The scientist regularly publishes in journals such as Cancer Research, OncoImmunology, Science Advances, and Annals of Oncology. Cancer Research is the most frequent venue for their work.

Best Publications

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Comprehensive molecular characterization of human colon and rectal cancer

    Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Comprehensive molecular characterization of gastric adenocarcinoma

    Adam J. Bass;Vesteinn Thorsson;Ilya Shmulevich;Sheila M. Reynolds

  • Integrated genomic characterization of endometrial carcinoma

    Gad Getz;Stacey B. Gabriel;Kristian Cibulskis;Eric Lander

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Eric A. Collisson;Joshua D. Campbell;Angela N. Brooks;Angela N. Brooks;Alice H. Berger

  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    Michael S. Lawrence;Carrie Sougnez;Lee Lichtenstein;Kristian Cibulskis

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Genomic Classification of Cutaneous Melanoma

    Rehan Akbani;Kadir C. Akdemir;B. Arman Aksoy;Monique Albert

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Integrated Genomic Characterization of Papillary Thyroid Carcinoma

    Nishant Agrawal;Rehan Akbani;B. Arman Aksoy;Adrian Ally

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • Telomere dysfunction induces metabolic and mitochondrial compromise

    Ergiin Sahin;Simona Colla;Marc Liesa;Javid Moslehi

  • DNA breaks and chromosome pulverization from errors in mitosis

    Karen Crasta;Neil J. Ganem;Neil J. Ganem;Regina Dagher;Regina Dagher;Alexandra B. Lantermann

  • Identification of Double Stranded Genomic DNA Spanning all Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer

    Christoph Kahlert;Christoph Kahlert;Sonia A. Melo;Alexei Protopopov;Jiabin Tang

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

Lynda Chin
Lynda Chin The University of Texas Health Science Center at Houston
Eugene R. Zabarovsky
Eugene R. Zabarovsky Karolinska Institute
Peter J. Park
Peter J. Park Harvard University
Eric S. Lander
Eric S. Lander Broad Institute
Ronald A. DePinho
Ronald A. DePinho The University of Texas MD Anderson Cancer Center
Raju Kucherlapati
Raju Kucherlapati Harvard University
Matthew Meyerson
Matthew Meyerson Harvard University
Gad Getz
Gad Getz Broad Institute
Jianhua Zhang
Jianhua Zhang The University of Texas MD Anderson Cancer Center
Michael S. Lawrence
Michael S. Lawrence Harvard University

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